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Clofranil (Clomipramine)

Clofranil is used generally for the treatment of obsessive-compulsive disorder but is also used to treat major depressive disorder, panic disorder and nerve pain. It is also used in the treatment of dual diagnosis disorders (mental health disorders and substance abuse combined). It is not recommended for bipolar disorder with manic and depressive episodes as it can induce mania in some patients. It can be used successfully for treatment of cocaine addiction as it helps prevent cocaine relapse. Clofranil should not be combined with stimulants such as amphetamines as it will enhance the action of the stimulant. Caution must be used with patients who suffer from cardiac conditions when prescribing Clofranil. Clofranil has a high rate of side effects relative to other SSRIs.

Other names for this medication:
Clomipramine, Anafranil, Clofranil, Clomipramina, Clora, Zenil,

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NMR studies of the alternative conformation of hammerhead ribozyme in the solution. We report here clinical, biochemical, and radiological findings of a patient with rheumatoid arthritis and multiple risk factors for fractures who was treated with alendronate for 8 yr and developed spontaneous bilateral subtrochanteric/diaphyseal fractures. Tizanidine (1 mg/kg) did not alter basal pH, acidity (free and total) of gastric content and did not produce any mucosal injury in fasted rats.

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