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Our results provide new information on the roles of Bmi-1 and HPV-16 E6 in the multi-step process of oral epithelial carcinogenesis. Metallothioneins (MTs) are ubiquitous metal-binding, cysteine-rich proteins, associated with metal accumulation and thus providing protection against toxic heavy metals such as cadmium (Cd). Microtubules visualized with a monoclonal anti-tubulin antibody are localized in the center of dendrites.

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Standard addition of fixed amounts of inorganic and methyl Hg standards into blood and urine were performed for recovery study. The aim of this project was to develop, validate and evaluate a reliable, specific test for vaginal fluid identification that would combine detection of vaginal mRNAs and Lactobacilli. Pleural calcification, pleural mesotheliomas, and bronchial cancers caused by tremolite dust. We analyzed individual patient data to determine the contribution of late postnatal transmission to the overall risk of mother-to-child transmission of human immunodeficiency virus type 1 (HIV-1) and the timing and determinants of late postnatal transmission.

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Outbreaks of influenza-like disease, time of vaccination and temporary closing of schools Combination of both methods yields good results in estimation of the haemodynamic significance of a renal arterial narrowing. Since we determined the same rate for the non-regenerating melanocytes and dermal fibroblasts, our data suggest that in human epidermis telomerase is a protective mechanism against excessive telomere loss during the life-long regeneration.

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The optimization of the modifier preparation and the instrumental parameters was investigated. We evaluated indications, laboratory results, and the clinical course. However, administration of successive doses resulted in a much delayed return to normal synthesis.

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Effects of telmisartan on renal excretory function in conscious dogs. The main outcome measure was a composite of death, assisted ventilation, or respiratory failure. Sepsis induces a state of growth hormone (GH) resistance associated with a decrease of circulating insulin-like growth factor (IGF) I, a GH-dependent anabolic hormone mainly produced by the liver. The DNA analysis revealed a 1.0 X:Y ratio of the spermatozoa before and after Percoll separation. Consistent with schizophrenia itself, during cognitive tasks, the risk (val) allele predicts less efficient prefrontal cortex (PFC) physiology and worse performance, while during aversive stimuli viewing, this allele predicts less limbic activation.

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Complex relationship between acquisition of beta-lactam resistance and loss of virulence in Streptococcus pneumoniae. Paclitaxel may be used in patients receiving long-term hemodialysis in the same dose schedule as in patients with normal renal function. Treatment of arterial insufficiency in the lower extremities by intra-arterial injection Hyperthyroid subjects showed, on the contrary, an expended distribution volume and a significantly higher excretion, as documented by a lower drug half-life, by the increase of the elimination constant and urinary digoxin output. In an attempt to answer some of these questions, this review discusses in detail pathologic and clinical features of GLILD and its proposed pathogenesis with a particular attention to potential role of human herpesvirus 8 (HHV-8).

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Some interesting characteristics of this radiation-induced growth arrest are that tumors do not die and shrink away as with some other tumor models but remain static in size and show histologic evidence of viable tumor cells. To determine whether sepsis and severe sepsis are associated with vitamin D deficiency and to determine whether vitamin D deficiency influences the severity of sepsis.

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Activity of CO was decreased bilaterally in the AlCl3-treated groups in all examined brain structures. K-ras mutations increased during tumour progression from bronchioloalveolar hyperplasia to adenoma. The study shows that tumour cell growth suppressant(s) and/or apoptotic triggers are present in tick salivary glands, however, further research into the characteristics and mode of action of such natural substances is necessary. Your frustration and anxiety with new technology will never change unless you take charge and communicate your needs to manufacturers. Rats received daily im injections of .02 mcg estradiol-17-beta/100 gm body weight, 2 mcg testosterone/100 (gm body weight, or estradiol plus testosterone for 1, 2, 3, 4, or 5 weeks from the day after castration.

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Since 24 states and the District of Columbia have legalized marijuana in some form, suppliers of legal marijuana have developed Cannabis sativa products for use in electronic cigarettes (e-cigarettes). Phenotypic and genotypic analysis of levofloxacin-resistant clinical isolates of Streptococcus pneumoniae collected in 13 countries during 1999-2000. Correlational analyses revealed that TP activity during perception of sad expressions, but not happy expressions, correlated with the neuroticism scores. We present a mixture of experts approach to biomolecular sequence labeling that takes into account the global similarity between biomolecular sequences. Endeavors to organize the Portuguese abroad and to preserve their link to their country of origin are also described.

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GnRH analogues in the prevention of ovarian hyperstimulation syndrome. The enhancement of Dolichos biflorus and certain other lectins using increased concentrations of sodium chloride. Modulation of MAPK and Akt signaling pathways in proximal segment of injured sciatic nerves. Molecular genetic studies of complex I in Neurospora crassa, Aspergillus niger and Escherichia coli. Semiconductor nanoplatelets (NPLs) are planar nanocrystals that have recently attracted considerable attention due to their quantum-well-like physics, atomically precise thickness, and unique photophysical properties such as narrow-band fluorescence emission.

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Cytokines play a key role in the pathogenesis of chronic Graft versus Host Disease (cGVHD) and various studies have shown abberant production of cytokines by immune cells from GVHD patients. The auditory threshold was controlled by the evoked potential of the brain stem. Thulium-doped fibers with ultra large mode-field areas offer new opportunities for the power scaling of mid-IR ultrashort-pulse laser sources. Anomalies not observed in P mice, developed in transgenerationally exposed mice, albeit, non-significantly. Treatment options for chemotherapy-induced anemia are transfusion of red blood cells and s.c.

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Electronic transport through a quantum dot strongly coupled to electrodes is studied within a model with two conduction channels. Total macular volume measurements were independent of observers. This study showed that the proliferative activity of BCC cells is associated with increased expression of HA in the tumour stroma.

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The examination showed that in healthy elderly subjects and centenarians most of the clinical laboratory findings were in the normal range. Serial observations provide information on progress of the disease and helps in the decision of the optimal time for surgery. Regimen complexity and type of assistance are independent correlates of medication nonadherence.

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Effects of phenobarbital and tobacco smoking on furosemide kinetics and dynamics in normal subjects. Several putative target genes were validated by quantitative PCR. The dynamics of the ligand-binding domain (LBD) and the intact ionotropic glutamate receptor (iGluR) were studied using Gaussian Network Model (GNM) analysis. Galanin can influence pituitary hormone secretion, intestinal motility, and other biological activities.

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This article reviews the treatment of types of urinary incontinence with behavioral therapeutic techniques. However, insulin-stimulated cell proliferation was completely abolished in the PKC-alpha depleted cells.

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A hapten generated from an oxidation fragment of docosahexaenoic acid is sufficient to initiate age-related macular degeneration. Both tape and glue significantly decreased the noise level produced by the toys.

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Competing risk analysis for life table data with known observation times. Isolation and characterization of a new bacterium capable of biotransforming cis -epoxysuccinic acid to D(-) -tartaric acid. This study examined one aspect of host-implant interaction- the effects of cochlear implantation with and without electrical stimulation on cochlear morphology in the guinea pig. Task force hopes to deliver affordable cancer drugs to developing countries. SHIELD-HIT calculations are compared with the experimental LET distributions for a carbon beam of energy 278 MeV u(-1) from the HIMAC facility in Japan.

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For the initial VWD diagnostics we measured VWF:Ag, VWF:RCo, platelet aggregation induced by ADP, ristocetin and collagen, closure time in the PFA-100 test, and platelet count. Sequential FeNO testing can accurately reflect asthma severity and provide for successful stepwise therapy for asthmatic children. Transoral microsurgery for treatment of laryngeal and pharyngeal cancers. All patients are basically suitable for early extubation, with the presence of preoperative risk factors used in this study being poor predictors of prolonged ventilation. In a preclinical model, NPRA expression has been identified during tumor angiogenesis and may serve as a potential prognostic marker and target for prostate cancer (PCa) therapy.

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Detection of right atrial and pulmonary artery thrombosis after the Fontan procedure by magnetic resonance imaging. laevis shows that claw formation is initiated at the tip of the toe by the appearance of superficial cornified cells that are dark brown. Facile synthesis of ultrathin magnetic iron oxide nanoplates by Schikorr reaction. A family history of atherosclerosis is independently associated with an increased incidence of cardiovascular events.

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Following 6-hydroxydopamine incubation (10(-3)M for 3h), the accumulation of noradrenaline was inhibited, contractile responses to noradrenaline were potentiated, responses to tyramine were abolished and responses to acetylcholine were unaltered. Genetic heterogeneity and the different impact of the candidate locus among populations could explain conflicting results obtained in different studies.

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Auto- and cross-correlation functions are calculated from the time histories with relaxation times of tens to hundreds of picoseconds. MEASUREMENT OF IMPROVEMENT: Three key indicators (percentage of vital signs taken by 9 am, drugs given as prescribed, and laboratory tests performed and documented) were tracked daily. In the crab scylla tranquebarica, bleeding stress is characterized by changes in proteins, lactic acid and water content of muscles, hepatopancreas and haemolymph.

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Guinea-pig lymph node lymphocytes were stimulated with mitogen (phytohaemagglutinin) in vitro and lymphocyte activation was measured by tritiated thymidine incorporation (DNA synthesis). Effects of stepwise dry/wet-aging and freezing on meat quality of beef loins.

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Depletion forces in the presence of electrostatic double layer repulsion. Well-arranged thin-layer nanoparticulate film, consisting of Y2O3 nanoparticles smaller than 20 nm, was obtained via spin coating of the W/O emulsion. Parenting practices and cognitions are associated with child externalizing behavior problems.

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They provide a basic reproduction number R0 for the spread of infection from individual to individual and a basic reproduction number RH0 for the spread of infection from household to household. Furthermore, it was found that the epitopes are highly conserved among JEV strains through sequence alignment.

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No significant difference was found between the average increase in metabolic rate over 3 h after an isoenergetic meal of food or of food plus alcohol. to mobilize PBPC in breast cancer patients to support high-dose chemotherapy (HDC). Hemodynamic effects of sublingual molsidomine in patients with or without cardiac failure Structural considerations suggested that CB 1954 might be acting as an inhibitor of poly(ADP-ribosylation).

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These metabolisms together with some oxidases are summarized briefly. The frequencies of mutants showed a high degree of interexperimental variability without any indications for synergistic effects of mixed beams. This general progress in the understanding of insulin action in man improves our approach to the complex pathophysiology of non-insulin-dependent diabetes mellitus and opens up new prospects for treatment of the insulin-resistant syndrome which is associated with several atherosclerotic risk factors.

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The relatively large size and the high rate of injuries in Neolithic crania and the practice of cannibalism are strongly suggestive of episodes of interpersonal or intergroup conflict. The authors analyze the mortality of the economically active population in Russia, with particular reference to the recent increases in mortality levels.

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Reciprocal homosexual mounting behavior in paired anosmic male rats. Cellular tropism, population dynamics, host range and taxonomic status of an aphid secondary symbiont, SMLS (Sitobion miscanthi L type symbiont). furcatus is based on a limited repertoire of basic kinematic modules but exhibits greater plasticity than previously thought. A total of 53 studies that included 68 datasets were eligible for inclusion in the final analysis. In a preliminary experience, pharmacomechanical catheter-directed iliofemoral DVT thrombolysis with early stent placement was safe and effective.

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To compare the test re-test reliability, sensitivity and specificity of different visual acuity and stereo acuity charts used in preschool children. The effect of cycloplegia on the visual contrast sensitivity function. Five patients ranging in age from 24 to 63 years with a histologically proven dural cavernous angioma were retrospectively included. Its presentation varies from a small plaque to multifocal nodules.

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This is the first report of 9-cis RA-dependent antagonism of thyroid hormone inhibition via negative TREs. Advances in our knowledge of the molecular-hormonal nature of ovarian cancer will help in designing a rationale for clinical trials in appropriate subsets of patients. This strategy is one that might be used in other nursing courses as well. A double-blind, placebo-controlled phase III study was performed to assess whether basiliximab, a chimeric anti-interleukin-2 receptor monoclonal antibody, reduced the incidence of acute rejection episodes in renal allograft recipients.