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Plastid and cytosolic phosphofructokinase from the developing endosperm of Ricinus communis. To predict the 1-octanol/H2O partition coefficient, log P, based on molecular structures, we calculated the solvent accessible surface area and the solvation energy difference of 166 organic molecules between 1-octanol and water environments with the ab initio molecular orbital self-consistent reaction field method, and then analyzed the relationships among the measured log P values with these two structural quantities by multiple linear-regression analyses. Helminths in calves on irrigated pastures on the transvaal highveld. The self-perceived role of general practitioners in care of patients with cardiovascular diseases.

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An exploration of the collaborative processes of making theatre inspired by science. Assessment of the effects of cetylpyridium chloride on water content of the collagen-keratocyte matrix of the mammalian corneal stroma ex vivo. Those pH-sensitive vectors promote membrane destabilization in endosomes upon the protonation of their histidine groups, allowing nucleic acid delivery in the cytosol. Independently, programs to increase the availability of primary and preventive services could substantially reduce ACS admissions. The results demonstrate that a considerable proportion of HL60 PLD activity is located in a detergent-insoluble fraction of the cell membrane that is unlikely to be a caveolae-like domain, but is probably cytoskeletal.

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The combination of choanal atresia and heart disease carries a very high risk. To verify whether the use of second generation ultrasonographic contrast agents leads to an improvement in the differential diagnosis of thyroid nodules, twenty patients, eligible for uninodular goiter surgery were studied. In vitro assessment of oxidative stress and apoptotic mechanisms of garlic extract in the treatment of acute promyelocytic leukemia. Proteins associated with proliferation were found in the nuclei of epithelial cells from the basal and suprabasal layers, whereas apoptotic proteins were detected in the cytoplasm of the upper layers of the epithelium. An obstructive biliary disease was ruled out with magnetic resonance imaging studies.

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Improved diffuse fluorescence flow cytometer prototype for high sensitivity detection of rare circulating cells in vivo. Endothelium dysfunction is present in arterial hypertension and dyslipidemia and the pathogenesis of atherosclerosis. At this time, both strong dermal and epidermal IgG staining was detected by indirect immunofluorescence microscopy on salt-split skin, and autoantibodies against both p200 and the 16th noncollagenous (NC16A) domain of BP180 were found.

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Estimation of daily ultraviolet radiation in Beijing using a semiempirical method. The relationship between diphenylamine structure and NSAIDs-induced hepatocytes injury.

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This review describes the postnatal development of responses mediated by the various receptors for adenosine and for nucleotides in the rat duodenum, colon, urinary bladder and vas deferens and considers the implications that this development may have for the importance of purinergic control in neonates and adults. For example, it is unclear whether Bak induces apoptosis in caspase 3-deficient cells. In the liver diffusely distributed nodules of regenerative hyperplasia were noted. This is the first direct demonstration that insertion of an MSL chromatin entry site on an autosome results in elevated expression in males of genes near the entry site.

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Development of recurrence is the main factor leading to deterioration in QOL over time after resection of HCC. Left thyrocervical trunk bronchial artery supplying right lung: source of recurrent hemoptysis in cystic fibrosis. Reduction of pre- and postexertion of the heart is one of the main factors of the protective action of molsidomin. In a trend similar to continuous electronic fetal monitoring, many hospitals are incorporating central fetal monitoring into labor and delivery suites.

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Information is included on changes over time, sex ratio, and country of origin. We performed a case-control comparison with the consecutive patients and an independent transmission disequilibrium test with the families. Tissue from the spinal cord and 13 different regions of the human brain were collected at autopsy within 24h from death. Detection of c-fos expression in benign and malignant musculoskeletal lesions. A neuropathologic study of Werdnig-Hoffmann disease with special reference to the thalamus and posterior roots.

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Shapes of plasma concentration curves after multiple administrations of HAPA-B were very similar to those after single administrations at all dosage levels tested. For a given repair, increasing abduction at neutral rotation reduced footprint contact.

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Family-centered maternity care (FCMC) developed as a consumer reaction to the depersonalization of birth that had been the management standard for childbirth during the first half of the century. IL-4 is a potent, pleiotropic cytokine that, in general, directs cellular activation, differentiation, and rescue from apoptosis. However, existing electrocardiographic (ECG) criteria for localization of accessory pathways have several limitations, and the polarity of delta waves has not been well defined. Subsequent results of Western blotting analysis revealed that this agent reduced detergent-insoluble phospho-tau. Sex hormone binding globulin concentrations in premenstrual syndrome.

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Engineered disulfide bond greatly increases specific activity of recombinant murine interferon-beta. The Korean experience: vignettes from cloister to chaos--and back. Climate change mitigation requires intensive actions to minimise greenhouse gas emissions in the future. Downregulation of c-Myc accompanied by induction of Mad1 upon differentiation has fueled the notion that Mad1 may play a role in the cessation of proliferation associated with the differentiation process. The effects of systemic morphine (1 mg/kg i.v.) on diffuse noxious inhibitory controls (DNIC) were studied in both sham-operated animals and those with quinolinic acid-induced lesions of the periaqueductal grey (PAG).

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Hypoxemia increases corrected QT dispersion (QTcD), which is the difference between the maximum and minimum QT intervals and is a strong risk factor for cardiovascular mortality. Genetic characterization of Toxoplasma gondii revealed highly diverse genotypes for isolates from newborns with congenital toxoplasmosis in southeastern Brazil. The research methodology was critically assessed and recommendations for future research were offered. We showed that human FOXL2 is sumoylated in transfected cell lines, and that endogenous mouse Foxl2 is comparably sumoylated.

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Patient characteristics (age, parity, and sociodemographic data), details of the procedures performed, and histologic findings were similar between the 3 surgical groups. siRNA knock-down of NgR1 resulted in a selective increase of GABAB R1 and GABAB R2 protein without altering the expression of GABAA receptor or GAD65. Development of a differential interference contrast thermal lens microscope for sensitive individual nanoparticle detection in liquid. The consistency of this effect throughout different time periods from diagnosis suggests that CRP does not have a large effect in predicting incident RA. The subjects were asked to simulate assembly operations using their bare hands, well-fitting gloves, and one size smaller or one size larger.

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Human visceral leishmaniasis: decrease in serum cholesterol as a function of splenic parasite load. The ordered chains give rise to a highly ordered single-layer structure with a (5x3) symmetry. Determination of neostigmine in human plasma and cerebrospinal fluid by high-performance liquid chromatography with ultraviolet detection.

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Sport meetings and banquets at 5 high schools in southwest Michigan during the fall, winter, and spring seasons. When pain levels are higher than usual, task-switching ability protects older adults from future declines in health. The gallstone, with its potentialy complications, claims a surgical solution in asymptomatic forms too, often traced out with the abdominal echography investigations circumstances. Participants were 125 elementary and 175 secondary school pre-service teachers from two Western Canadian universities. We have used the technique of in situ hybridization histochemistry to determine corticotropin-releasing factor (CRF) mRNA in the hypothalamic paraventricular nucleus (PVN) and proopiomelanocortin (POMC) mRNA in the anterior pituitary of rats given a single ip injection of either interleukin (IL)-2 or IL-4.

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CPT also caused the increase of free radicals concentrations in the examined natural melanin. Long term cocoa ingestion leads to an increased resistance against UV-induced erythema and a lowered transepidermal water loss. Recent studies have shown that different populations of trophoblastic cells of first-trimester human placenta express human chorionic gonadotropin/luteinizing hormone (hCG/LH) receptors. Plasma samples containing PMEA, HPMPA, or FPMPA were treated with chloroacetaldehyde to yield the corresponding highly fluorescent 1,N6-ethenoadenine derivatives. Two additional families with partial phenotypes and atypical 7q11.23 deletions were studied.

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In simulation studies, the HSC method has a correct type 1 error rate in both unstructured and structured populations. Arrests, readmissions and treatment following release from detoxication centers. Terminal regions of the NS-1 protein of the parvovirus minute virus of mice are involved in cytotoxicity and promoter trans inhibition. However, in cdc6 and cdc14 mutants, the mitotic loss of pDK243 with an ARS cluster was suppressed by a factor of 6-8 compared to pDK243 without the cluster. Significant differences were observed between C1236C and C3435T and also C1236C and C3435C.

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Multivariate logistic regression analysis was used to determine risk factors. Isolation and characterization of lamellar aggregates of LHCII and LHCII-lipid macro-assemblies with light-inducible structural transitions. Comparison of accidental and nonaccidental traumatic brain injuries in infants and toddlers: demographics, neurosurgical interventions, and outcomes. OmpF-Lpp signal sequence mutants with varying charge hydrophobicity ratios provide evidence for a phosphatidylglycerol-signal sequence interaction during protein translocation across the Escherichia coli inner membrane. To study the induction of heat shock protein (HSP) of normal human skin, the indirect immunofluorescence method, using monoclonal antibody directed against 72-kD HSP, was applied in organ-cultured normal human skin that was treated with heat, UV, or chemicals.

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Changes in HIV risk behavior following alternative residential programs of drug abuse treatment and AIDS education. This retrospective cohort study compared appropriate VTE prophylaxis prescription for all patients admitted to the adult trauma service from July 1, 2012 to May 31, 2015 at The Johns Hopkins Hospital, an academic hospital and Level 1 trauma center in Baltimore, Maryland. Effects of fluorescein and indocyanine green angiography on subsequent dark adaptation and the electroretinogram

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Genetic variants in peroxisome proliferator-activated receptor gamma influence insulin resistance and testosterone levels in normal women, but not those with polycystic ovary syndrome. State of the physiological system of connective tissue in children with exudative diathesis

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The root extract at a dose of 5.0 g/kg body weight showed highest hypolipidaemic effect. Bandwidth selection and reconstruction quality in point-based surfaces. Caffeine Induces a Stimulant Effect and Increases Dopamine Release in the Nucleus Accumbens Shell Through the Pulmonary Inhalation Route of Administration in Rats. Unfortunately, the behavioural toxicity of many xenobiotics is still unknown, warranting their future study.

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The presence of labor preceding cesarean section did not reduce the risk of RDS significantly, although a trend, not statistically significant, was noted in this direction. US National Survey of Physician Practices for the Secondary and Tertiary Prevention of Ischemic Stroke. Association of retinopathic progression with risk factors was tested with chi 2 and multiple logistic regression analysis.

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This paper reviews the role of oxidative stress in the onset and progression of damage in different eye structures, the involvement of the antioxidant network in protecting and maintaining the homeostasis of this organ, and the potential assessment methodologies used in research and in some cases in clinical practice. At the present time, there is insufficient evidence in the literature to recommend routine nutritional supplementation in healthy adults for primary prevention of AMD. With respect to the great ape condition, the human trabecular pattern is characterized by a distinctive ilioischial bundle, an undivided sacropubic bundle, and a full diagonal crossing (approximately 100 degrees) over the acetabulum between the ilioischial and the sacropubic bundles.

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To determine the correlation of PaCO2 and ETCO2 during operations for lumbar disk herniation in prone position: the influence of position and deliberate hypotension. The organism producing an aminoglycoside antibiotic complex was subjected to selection with a purpose of obtaining a strain producing tobramycin. A capsulo-ligamentous structure on the medial aspect of the piso-triquetral joint was also identified.

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There is a pressing need for physicians to increase their confidence and competence in managing these patients. The resulting rising number of diseases that can be prevented by vaccination, coupled with the growing trend of preferring cost-effective preventive medical interventions over expensive therapeutic modalities, has increased the complexity of administering to all those who need them, the many different vaccines that will soon be available.

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17alpha,20beta-Dihydroxy-4-pregnen-3-one (17alpha,20beta-DP) was identified as the maturation-inducing hormone of several teleosts, including Nile tilapia. CLON significantly increased focal and generalized seizure thresholds, whereas IDA significantly reduced seizure thresholds when compared to controls. These results suggest that the model provides an accurate description of the EHG AP and the volume conductor, with promising perspectives for future applications. The striking clinical and pathological features of this rare benign tumour-like lesion are described and illustrated. We quantified optic disc pallor in patients with pseudotumor cerebri with the Rodenstock Optic Nerve Head Analyzer before and after optic nerve sheath decompression.