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In this paper, we show that the case-only design is also a valid and efficient approach to measuring gene-gene interaction under the assumption that the frequencies of genes are independent in the population. Nanocrystals with different shapes provide diverse building blocks for bottom-up approaches in building nano- and mesosystems. Effects of carbon dioxide embolism with nitrous oxide in the inspired gas in piglets. From 15 min to 12 hr after thermal injury, luciferin-dependent chemiluminescence activities were significantly higher than that of the control group.

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Etodolac, a selective cyclooxygenase-2 inhibitor, induces apoptosis by activating caspases in human malignant rhabdoid tumor cells (FRTK-1). Monte Carlo simulations are presented for the static properties of highly branched polymer molecules. Recent advances have focused on the utility of alkyltrifluoroborates in appending alkyl groups selectively and conveniently onto appropriate molecular substructures. Langendorff-perfused guinea-pig hearts were subjected either to 30 min global ischemia/30 min reperfusion (IR) or were preconditioned prior to IR with three cycles of either 5 min ischemia/5 min reperfusion or 5 min infusion/5 min wash-out of mKATP opener, diazoxide (0.5 microM).

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Mouse medullary thymocytes have specific receptors for 1,25-dihydroxyvitamin D3 (1,25(OH)2D3). Measurements of transverse ion beam emittance generated by high current ion sources at the GSI test injector facility HOSTI. Environmental factors affecting nutrition and compliance in the pubescent individual also affect success in achieving desired pharmacologic effects while minimizing toxicities. Antibodies reactive exclusively with human NCAM immunoprecipitated both proteins but failed to coprecipitate any other proteins. Although molecular genetic alterations have been characterized in human astrocytomas, many of the mice engineered with these mutations do not develop astrocytomas.

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While the double logistic model gives an adequate fit to the observed height curve, differentiating it leads to a height velocity curve which differs considerably from the observed velocity curve. Binding of radiolabeled bacteria to blots of erythrocyte membrane proteins revealed binding to the poly-N-acetyllactosamine-containing components Band 3, Band 4.5, and polyglycosyl ceramides and to glycophorin A.

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The procedure involves impregnation of the specimen with uncured polymers--a silicone rubber of medium viscosity followed by curing in a vapor bath. Sea urchin spine injury--a case report of chronic synovitis of the foot The value of CT in diagnosis and prognosis of different inborn neurodegenerative disorders in childhood. influenzae strains may also be influenced by the mucin interactions of the strains.

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This study reviews some of our experiences in the investigation of a variety of lesions within the orbit and attempts, in particular, to illustrate the value of direct coronal studies. The syndrome is subdivided into two categories: motor and sensory urge incontinence. Conventional rehabilitation programs, including body weight-supported walking or robotic assistance, that modify sensory feedback intended to alter lower extremity movement patterns have shown limited success in improving gait symmetry. This report describes the MR findings in a patient with cystic angiomatosis of bone. LTD was measured by echography and correlated with histological and cytogenetic findings and metastatic death.

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Adjuvant chemotherapy in resectable cholangiocarcinoma patients. Ecological models in support of regulatory risk assessments of pesticides: developing a strategy for the future. The tumorigenic population continued to actively divided and produced a large progressively growing tumor. The development of the population of Abidjan, capital of the Ivory Coast, is analyzed using data taken primarily from a multi-round survey conducted in 1978-1979. Effect of an autogenous free fat graft on hemilaminectomy defects in dogs.

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In the present study, we used multiple mass spectrometry techniques to investigate the formation of HMVK adducts with nucleophilic residues of Hb in vivo after dosing Sprague-Dawley rats with 25 and 200 mg/kg BDD. It was shown that leu-enkephalin administration suppressed, while met-enkephalin injection stimulated granulocyto- and erythropoiesis during immobilization stress. Molecular analysis has shown that the ph locus contains two transcriptional units coding for two very similar proteins.

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Histological examination revealed a significant reduction in the number of nerve cell bodies in the lateral hypothalamus. Because erythropoietin (EPO) levels have been found to be low (i.e., normal) in these previously transfused patients despite the degree of anemia, we treated four affected infants with EPO, 200 microliters/kg subcutaneously three times a week, and noted reticulocytosis and increased hemoglobin values 2 to 4 weeks later. Zinc finger nucleases (ZFN) mediate transgene integration into the AAVS1 locus but comprehensive evaluation of off-target genome effects is currently lacking. Paucity of intrahepatic bile ducts, solitary kidney and atrophic pancreas with diabetes mellitus: atypical Alagille syndrome?

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The Beat to Read: A Cross-Lingual Link between Rhythmic Regularity Perception and Reading Skill. Racial differences exist in the effects of health insurance coverage and household income on household medical visit expenditures, and both need and household size are found to be consequential determinants of demand.

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Clinicians and researchers should consider methodological shortcomings when evaluating estimates of harms associated with clinical interventions. The aim of this study was to determine the association between metabolic syndrome (MetS) and demographic, health, and lifestyle characteristics in a sample of women living in Puerto Rico. A single lesion of the spinal cord is a rare presentation of acute disseminated encephalomyelitis, the course of such lesions, to date not previously displayed by MR, is unknown. Sight-threatening complications of SLE include retinal vaso-occlusive disease and optic neuropathy. In this paper, we present a model that suggests modifier processes (MPs), which are not necessarily specific to the syndrome refractor alter the expression of autism and contribute to fundamental behavioral and psychological differences in children diagnosed with this disorder.

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the physician can rely on the correct count of abdominal sponges, swabs etc. Little is known about the voltage-dependent potassium currents underlying spike repolarization in midbrain dopaminergic neurons. Non-Hodgkin lymphoma involving the tracheobronchial tree is rare. Beyond this, periodic superlattice structures present a solution to decouple physical properties where the underlying electronic interaction is governed by different length scales. The United States health care system is at a pivotal point in its ability to manage chronic illness.

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Histological study of those animals which die from 3 to 11 months after treatment reveals a chronic progressive glomerulonephritis with generalized vascular lesions. Steady-state bioavailability of two sustained-release quinidine preparations: quinidine gluconate versus quinidine sulfate. Thermal fluctuations cause perturbations of fluid-fluid interfaces and highly nonlinear hydrodynamics in multiphase flows.

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Pseudoxanthoma elasticum is an incurable, autosomal-recessive, genetic disorder that is caused by mutations in the ABCC6 gene. Initially, the blebs are small, the tegument surrounding the spines is swollen and the tegument generally has a smooth, swollen appearance. Estrogen Drives Cellular Transformation and Mutagenesis in Cells Expressing the Breast Cancer-Associated R438W DNA Polymerase Lambda Protein.

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The electronic properties of Cu-phthalocyanine (CuPc) molecules flat lying along the channels of the Au(110) reconstructed surface have been investigated by means of ultraviolet and x-ray photoelectron spectroscopy. To extend beam pulse width, a solenoid field was applied at the drift space of the LIS at Brookhaven National Laboratory. Approximately 7 min after injection, MSNA and heart rate were again notably increased, followed by an increase in blood pressure.

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This study compared the identification of 50 Chinese and 50 comparable English words by 17 Chinese and 17 English participants, respectively. Antihypertensive and metabolic effects of long-term treatment with amosulalol in non-insulin dependent diabetics. Thus, mutations within the RB gene (or splice-site mutations with exon-skipping) and apparent mutations of the p53 gene together may have contributed to the development of three of these tumours or to the establishment of these cell lines.

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The therapy was continued for two additional months in patients with stable or responding disease. The general behavior, adverse effects and mortality were recorded for up to 14 days post treatment. An autopsy case of deep cerebral venous thrombosis: serial CT, MRI and pathological findings Use of the neodymium:yttrium-aluminum-garnet laser for treatment of squamous cell carcinoma of the nasal planum in a cat.

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The DNase I cleavage pattern is not identical at each of the maxima, suggesting that the structural distortions imposed by the core particles are not constant along the DNA. Histochemical phenol oxidase demonstration--an auxiliary means of determination immunologic defense processes in tumors?

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While the agglutination test is very sensitive in detecting sporotrichosis, it does not differentiate active disease from inactive disease. Other drugs commonly used in combination with fluorouracil did not interfere with the assay.

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Cholinergic nerve fibers are present in human pancreatic islets, and appear to be organized in an external peri-insular plexus. The current study showed a clear difference between the protein profiles of CSF from patients with PE and normotensive pregnant women. Concomitant pulmonary and central nervous system paracoccidioidomycosis with cerebellar abscess. The use of head-mounted display eyeglasses for teaching surgical skills: A prospective randomised study. Neocortical projections of the suprageniculate and posterior thalamic nuclei in the marsupial brush-tailed possum, Trichosurus vulpecula (Phalangeridae), with a comparative commentary on the organization of the posterior thalamus in marsupial and placental mammals.

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Localization of aldosterone synthase cytochrome P-450 (cytochrome P-450aldo), a recently identified enzyme that converts deoxycorticosterone to aldosterone in rat adrenocortex was strictly confined to two or three outermost cell layers in the zona glomerulosa. A comparison of the relative efficacy of self-control therapy and a behavioral problem-solving therapy for depression in children. Successful optimization of networks with many fewer interneurons showed that the 40-interneuron network is redundant, raising the possibility that the interneurons have additional functions. A case with post-cataract surgery corneal oedema referred for endothelial keratoplasty. Disruption of the SCL locus in T-lymphoid malignancies correlates with commitment to the T-cell receptor alpha beta lineage.

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Using repeated measures, neonatal and maternal heart rate, oxygen saturation and respiratory rate were recorded along with neonatal behavioral state and maternal anxiety state. We determine the bifurcation phase diagrams with isotropic (I), uniaxial (N(U)) and biaxial (N(B)) nematic phases for model bent-core mesogens using Onsager-type theory. Effect of skin coverage method following subcuticular suturing on wound infection rates at cesarean delivery. However, striated muscle alpha-actin or desmin antibodies did not stain cardiac fibroblasts but did stain cardiac-muscle cells. They are also recognizable in electron micrographs by their characteristic 1,000 to 3,000 A dense-core granules.

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However, there have been no studies investigating the effects of running exercise on the total volume, total length and total surface area of the capillaries in the cortex. Previous studies show that hysterectomy on Day 1 of pseudopregnancy prolongs serum progesterone secretion in estrogen-treated pseudopregnant rabbits. The human class I histocompatibility antigen HLA-A2 has been assembled from subunits expressed separately in E. As a consequence of effect of losartan, we singled out the nonlinear parameters SD2 and DF2.

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The science of sports injury control, including both its cause and prevention, has largely been informed by a biomedical and mechanistic model of health. Additional research is warranted to determine the actual functions of TLC in tears and the presence of its receptor on the ocular surface. The maximal responses frequently are slightly larger than the recorded resting potential but the apparent small overshoot may be due to difficulty in recording the full resting potential.

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The results demonstrated that ligand-induced autophosphorylation capacity and basal phosphotyrosine residues of plasma membrane EGFR were both decreased parallel with the decrease in EGFR protein, suggesting no TCDD-related alteration in the inherent functional ability of the receptor to undergo activation. Methylation of the ABL1 promoter in chronic myelogenous leukemia: lack of prognostic significance. Human host cell factor-1 (HCF-1) is essential for cell cycle progression and is required, in conjunction with the herpes simplex virus transactivator VP16, for induction of viral immediate-early gene expression. Spectacular cure by regional sympathetic block with guanethidine

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The feasibility of using PCR-direct sequencing for the rapid sequence determination of large-subunit rRNA genes is demonstrated. Non-steroidal anti-inflammatory drugs and antidepressants, a dangerous combination

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There was one death in the single-stage group due to massive fat embolus. Prolonged tumescence occurred in four patients, two of whom required treatment with intracorporeal metaraminol. A close correlation between preoperative risk and postoperative length of stay in the ICU was found. Evaluation of a pinna compensation algorithm for sound localization and speech perception in noise. The purpose of the present study was to evaluate the anatomic features of the cervical spine using computed tomography (CT) to select safer screw insertion techniques, particularly emphasizing the location of the transverse foramen.

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A suggestion has been made concerning the appearance of a new V. The human bocavirus (HBoV) is a newly recognized human parvovirus first reported in 2005. These results highlight the need for further investigations of the interactions between depression and NUPM, particularly to evaluate potential causal relationships. To date, interaction surfaces have been proposed on the basis of unusual physical properties, unusual propensities for particular amino-acid types or an unusually high level of sequence conservation.

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The attenuation of metal/peroxide oxidative chemistry, as well as lipid peroxidation, appears to be the major chemical mechanisms by which NO may limit oxidative injury to mammalian cells. When emergency occurs (such as herbicide treatments or environmental stresses followed by ABA and ROS accumulation), the master transcription factor ABI4 down-regulates some TFs, like CBFA, and then some other TF subunits enter the transcription complex and transcriptional efficiency of stress-responsive genes (including the transcription co-factor CBP) is improved instantaneously. p16(INK4a) has been explored as a biomarker for screening in general populations. DNA array reveals altered gene expression in response to focal cerebral ischemia. No increase was detected throughout the observed time in the contralateral side.

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A Comprehensive Study of Osteogenic Calcium Phosphate Silicate Cement: Material Characterization and In Vitro/In Vivo Testing. Moreover, in the penile urethra the dorsal placement of the graft is now combined with the incision and the augmentation of the urethral plate, as suggested for childhood hypospadias surgery. Effect of maternal undernutrition on vascular expression of micro and messenger RNA in newborn and aging offspring.

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