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To report a novel mutation of the ABCC6 gene in a Japanese family that had a case of pseudoxanthoma elasticum (PXE) another with PXE and retinitis pigmentosa. Intergeneric somatic cell nucleus transfer in marbled cat and flat-headed cat. Spontaneous remyelination following extensive demyelination is associated with improved neurological function in a viral model of multiple sclerosis.

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Stimulation of area V5, however, severely disrupted performance on the same task. Identification of these KD mutations is essential in order to direct alternative treatment strategies in such CML patients. This change in gene expression indirectly inhibits the YAP/TAZ co-activators, which maintain the clonogenic potential of these cells. Can biophysics tell us something about the weak equivalence principle vis a vis the thought experiment of Einstein involving human subjects?

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Anti-mesothelin antibodies were assessed by immunoassay of sera from hens with normal ovaries and with ovarian tumors. This report describes testing of a case of in utero drugs of abuse exposure in which discordant results were seen between urine and meconium, and between twin meconium samples. Dynamic changes and roles of steroid hormones in the perinatal period

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Outcome and risk factors for recurrence in malignant ovarian germ cell tumors: a MITO-9 retrospective study. A biochemical survey of 4,000 parents of mentally retarded children did not identify any mothers with elevated phenylalanine blood levels. However, to confirm this conclusion, multicenter studies, among considerably larger populations, are necessary. Dermal fat grafts have been utilized in plastic surgery for both reconstructive and aesthetic purposes of the face, breast, and body. Mycoplasma penetrans is a mycoplasma with unique morphology, recently identified in urine samples collected from HIV-infected patients.

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The edentulous mandible opposing maxillary natural teeth: treatment considerations utilizing implant overdentures. The purpose of the review was an analysis of the different techniques of the radial forearm flap with respect to urethral construction in forming a phallus in female to male transsexual patients.

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Partial remission was accomplished in cancers of the breast and oesophagus. It was shown that the FITC-peptide can be attributed to the sequence Gly (379)- Arg (400) and that the label is selectively bound to Lys (384). The authors state that these results represent a new nosographic entity associated with the condylar mandibular fractures with important clinical, insurance and legal repercussions. The findings of the search were discussed with public health specialists to determine whether or not they used these resources. Preliminary studies for a possible use of Doppler signals in the analysis of systolic time intervals of fetal heart.

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Inservice education: an evaluation of the preceptor model versus the formal teaching model. This includes providing appropriate support to pharmacy support staff.

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The use of isobutyl cyanoacrylate tissue adhesive is a simple, quick, and inexpensive method for placement of external eyelid weights for temporary treatment of ocular exposure associated with facial paralysis and for determining the correct weight for implantation. Although not US Food and Drug Administration approved for benign disease, fully covered self-expandable metal stents are increasingly being used in a variety of benign biliary conditions. Beta-lapachone suppresses radiation-induced activation of nuclear factor-kappaB. Leprechaunism: an inherited insulin resistance syndrome caused by the defect of insulin receptor A sensitive method is presented for measurement of changes in the permeability of mitchondria in cultured cells.

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Systems with coupled cavities and waveguides have been demonstrated as optical switches and optical sensors. Effect of an acute dose of ethanol on the hepatotoxicity due to carbon tetrachloride. Both cohorts experienced major reduction in their quality of life from chronic pelvic pain and urinary symptoms. Effects of lindane on growth of cellular slime mold Dictyostelium discoideum.

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Current therapies have not proved to be particularly effective in preventing or reversing damage to the spinal cord. Polymethoxylated flavones (PMFs), as potential cancer chemopreventive agents, are widely distributed in Citrus genus. Rubber latex injections indicated that the main perfusion pathway was unilateral via the middle, anterior, and posterior cerebral arteries.

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Plasma concentrations of VX-710 in patients who received at 120 and 160 mg/m(2)/h were two- to fourfold higher than concentrations required to fully reverse drug resistance in vitro. Briefly, we used a cocktail of dexamethasone, insulin, methylisobutylxanthine (DIM) plus a peroxisome proliferator-activated receptor gamma agonist, rosiglitazone (DIMRo) as a new adipogenic differentiation medium.

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Our study provides a theoretical foundation for the selection of favorable metal electrodes in ML/BL WSe2 devices. The genus Vitex, which belongs to the Verbenaceae family, includes approximately 250 species. Hospitalist programs, which are staffed by clinicians highly skilled in caring for inpatients, are being launched with the aim of delivering high-quality, efficient medical care in an increasingly competitive health care delivery environment.

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Head-to-head comparison of an intradermal and a virosome influenza vaccine in patients over the age of 60: evaluation of immunogenicity, cross-protection, safety and tolerability. Cell size, calmodulin content and inhibition studies using W13 did not reveal any simple correlations for the RCC cell lines, although the RCC lines did have a higher content than the fetal kidney cell lines. Exerting a force on a mechanical system can induce mechanical instability. The combined application of two photosensitisers (PSs), zinc(II) phthalocyanine (ZnPc) and the cationic porphyrin meso-tetrakis(4-N-methylpyridyl)porphine (T4MPyP), on HeLa cells produced an enhanced lethal effect relative to treatments with single PSs.

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Dosimetric accuracy in radiation treatment of breast cancer is critical for the evaluation of cosmetic outcomes and survival. These results suggest that the drug dust control systems of individual dispensaries should be properly installed and managed. Based on amino acid sequence homology, promoter DNA sequence homology and in silico gene expression analysis, RPL5B was found to be putatively functionally redundant with RPL5A. Thus, siRNA can be a potential alternative to the standard HSE treatment especially to reduce clinical signs and extend survival time in vivo. In order to exclude associated MI in cases of blunt chest trauma, electrocardiography is necessary, and coronary angiography may be indicated to demonstrate coronary arterial pathology.

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The effect of electrolytes (NaCl and CaCl2) on creaming, particle size and electrophoretic mobility showed both minimum stability and minimum zeta potential at 3 X 10(-3) mol dm-3 CaCl2 and at 2.5 X 10(-1) mol dm-3 NaCl. Patients proposed group-based patient education with lay educators with a stoma to make sure that information about the stoma was based on real-life experiences. However, robust prospective studies are difficult to implement in resource-poor settings.

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We identified PW1 as a potential Hsp70 partner by screening for proteins interacting with PW1. Anesthesia rapidly suppresses insulin pulse mass but enhances the orderliness of insulin secretory process. According to bioinformation analysis of the cDNA sequence, a specific fragment of FAD2 gene was isolated by RT-PCR from immature maize embryos, and DNA of the same length was amplified from maize genome. The aim of the present study was to assess the association between facial attractiveness and regional facial asymmetries evaluated on three-dimensional (3D) images. Role of hapten-anchoring peptides in defining hapten-epitopes for MHC-restricted cytotoxic T cells.

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Urologists performing repeat vasectomy reversal must be familiar with microsurgical techniques, since almost three-quarters of patients will require at least unilateral vasoepididymostomy. Literature for this paper was retrieved from a variety of sources including the nonmedical press, editorials, peer-reviewed journals, Department of Health and Human Services regulations, National Institutes of Health policy, the Belmont Report, and regulations of the Food and Drug Administration. Titration studies of Cd-binding alpha-fragment, the carboxyl-terminal half of human metallothionein-2, which was independently expressed in Escherichia coli as a Cd-binding form, with Cu were performed. Among the described activities several were related to inflammation and immunity such as its regulatory activity on complement. Therapeutic effects of larger doses of arachidonic acid added to DHA on social impairment and its relation to alterations of polyunsaturated fatty acids in individuals with autism spectrum disorders

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Kinetic mechanism and substrate specificity of nitroalkane oxidase. A strong positive correlation was found between faecal fat and faecal mass and between the respective changes caused by GFD in these variables, whereas the correlations between faecal bile acids and faecal volume or between these changes caused by GFD were weak or nonsignificant. Recent studies employing knockout mice suggest that the T(H)-1 cytokine interferon-gamma is an important cytokine in amplifying the local immune response of lupus nephritis. There is a high incidence of persistent pain after traumatic injury, even in patients with relatively minor severity of injury.

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The aim of this study was to examine relations and influences between work-related factors, personal resources, work engagement and work ability of surgeons working in German hospitals. However, heat-treated TCM significantly lost the inhibitory activity against larval development of P. The intrauterine device (IUD) is of little or almost no relevance for young women undergoing treatment with a retinoid. Pitfalls in determining IgG and IgG subclass antibodies to food antigens.

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Disinfection of the samples was determined based on presence or absence of turbidity in the BHI broth 96 hours later. A retrospective review was done of consecutive cases of PKP performed between January 1, 1997, and December 31, 2001, for keratoconus, corneal edema, stromal scarring, and stromal dystrophy. The HLA-B27 antigen is present in only 4 per cent of black American male subjects and may be important in the diagnosis and management of patients with primary retroperitoneal fibrosis. A method is presented to calculate the optimal drug concentration pair to produce the half-maximal combination effect. A case of esophageal carcinosarcoma treated effectively with endoscopic polypectomy and irradiation

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So far, there exists no clinical data whether PXE patients actually are at high risk of developing pulmonary disorder. Results showed that repeated exposure was required for development of anti-bromelain antibodies, with strong antibody responses in all mice that received at least 12 doses of bromelain either orally or intragastrically over 3-6 weeks.

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Subsequently, the population of keratinolytic fungi in sediments was found to be clearly dependent of the degree of water contamination with sewage. In another group of seven rats the same delays were introduced in a quasi-random order and alternated with uninterrupted trials. Ventilation-perfusion (Va/Q) inequality was measured by a multiple inert gas elimination method in 6 asymptomatic patients with asthma and in a seventh patient during a severe asthmatic episode. The Steroidogenic Acute Regulatory (StAR) protein produced by the fetal Leydig cells was dramatically reduced in the DES-exposed testes. Monthly and seasonal fluctuations in abomasal nematode worm burden of naturally infected cattle in Austria.

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Cell culture techniques, high-resolution in vitro 1H nuclear magnetic resonance (NMR) spectroscopy, and chromatographic analyses were used to compare the properties of purified cell populations derived from the PNS and cortical neurones. Whereas our previous designs employed solely a maleimide pharmacophore for achieving the two crucial canonical hydrogen bonds to the hinge region of the ATP binding site, we have now extended our investigations to include the related lactam metallo-pyridocarbazoles. On the coherent components of low-frequency ambient noise in the Indian Ocean. Activation of neutrophils NADPH oxidase by PMA: cytosol activity is translocated in phorbol-primed neutrophils.

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Loss-of-function mutation in RUSC2 causes intellectual disability and secondary microcephaly. Degradation of serum amyloid A protein by surface-associated enzymes of human blood monocytes.

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coli O157:H7, which indicated a good correlation with the IgG titer. Its diagnostic accuracy equals that of currently used single-disorder screens and has the additional benefit of being combined into a 1-page tool. Only the patients who carry an allele with expansion in the ataxin-3 gene presented with clinical symptoms. Capsullary and intranodal arterial flow rates were measured and maximal systolic, end-diastolic, mid-systolic flow velocities with pulsatility, resistivity and acceleration indices were obtained.

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These pigments, which have an absorption maximum at 580 nm in alkaline solution, were separated isocratically on an alkali-resistant ODS column by paired-ion chromatography. An improved numerical model for calculating the ultrasonic power deposition in layered medium was developed and experimentally tested.

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MRI gives us an information of the location and numbers of leiomyoma in the uterus. One third of the subjects attended the facility-wide oral education program.

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Laminin on Toxoplasma gondii mediates parasite binding to the beta 1 integrin receptor alpha 6 beta 1 on human foreskin fibroblasts and Chinese hamster ovary cells. Registration of images with missing correspondences, such as in the alignment of preoperative and postresection brain data, is a difficult task. Moreover, we have silenced one of the antimicrobial peptides (AMPs) controlled by REL2, defensin A, a major AMP in A. As in arthroscopy, assessment of injuries to the menisci, articular surfaces, synovium, and cruciate ligaments can be made. In contrast, receptor activity toward the sweetener cyclamate and the sweet taste inhibitor lactisole depends on residues within the transmembrane domain of human T1R3.

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Another patient had invasive fungal disease and developed orbital apex syndrome. Similar evoked responses were obtained to a full field optokinetic stimulus approximating to that of the movement of the chair. Thermal Diffusion Processes in Metal-Tip-Surface Interactions: Contact Formation and Adatom Mobility. However, the association between aging and degeneration of the extracellular matrix (ECM) in tendons has not been investigated extensively.

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Co-relationships between glandular salivary flow rates and dental caries. We also revealed that Nanog regulated cell proliferation by modulating the expression of cyclin D1/D3/E1 and CDK2, respectively. With these approaches, the role of Prdx6 in Nox2 activity can be explored with intact cells.

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Using regression analysis, we estimated the effect of being in each of the cancer care groups on out-of-pocket medical expenditures, the probability of being employed, and the annual number of workdays missed because of illness or injury. Apparent aggregation among random individuals in random broods fell 8-fold when spatial and temporal effects had been accounted for. Out-patient chronic pain service in Hong Kong: prospective study. Knock-down of Bmptp-h by RNA interference significantly inhibited viral replication, and over-expression enhanced viral replication as determined by viral DNA abundance and BmNPV-GFP positive cells.

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Type II intrauterine growth retardation may exert a profound effect on renal development. Degradation is estimated based on two models, the fixed and the general model. Changes in gene expression for gonadal development were also observed after exposure to DE. Coxsackievirus infections are associated with severe diseases such as myocarditis, meningitis and pancreatitis. Data were collected through the Safety Attitudes Questionnaire (SAQ - Short form) and the Context Assessment Index (CAI).

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Non-prostanoid thromboxane A2 receptor antagonists with a dibenzoxepin ring system. We report that there was an age-related increase in the activity of superoxide dismutase without concomitant changes in the activity of catalase or glutathione peroxidase and an age-related decrease in the concentrations of alpha-tocopherol and ascorbate. Determination of L-ascorbic acid and total ascorbic acid in vascular and nonvascular plants by capillary zone electrophoresis. The results suggest that breakpoint 1q21 may be related to tumorgenesis and may be useful in screening and preventing colorectal carcinoma. Evaluation of the E test method in the antimicrobial sensitivity of Neisseria meningitidis to penicillin

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A SpeI-AvaI fragment (0.3 kbp) from pBbi16 (a pBR322 derivative containing a 6.3-kbp Babesia bigemina DNA insert) was subcloned into the pBluescript phagemid vector and was sequenced by the dideoxy-mediated chain termination method. This review provides an overview of the biosensor technology available today, areas which are currently being developed and researched for cancer markers diagnosis-and a consideration of future prospects for the technology. Effect of benzamide on cell growth, NAD and ATP levels in cultured chick limb bud cells. Congenital urethral duplication is a rare anomaly, with less than 200 cases described in the literature.

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The combination of moderate-dose CDDP and alpha-IFN as administered in this schedule is well tolerated and possesses encouraging activity in metastatic melanoma. These resistant isolates had an identical ribotype and nearly identical pulsed-field gel electrophoresis (PFGE) patterns. Respondents indicated: a) whether or not they would prescribe antibiotics before dental treatment in 10 cardiac conditions, b) if antibiotic prophylaxis was reasonable before 10 dental procedures in an endocarditis high-risk patient, and c) a prescription for oral antibiotics for an endocarditis high-risk non-allergic adult about to undergo a dental procedure. Detection and clinical manifestation of placental malaria in southern Ghana. Spreading of colloid clusters in a quasi-one-dimensional channel.

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Recent guidelines for diagnosing autoimmune urticaria have been proposed, but further investigation is needed. Successful treatment of perianal giant condyloma acuminatum in an immunocompromised host with systemic interleukin 2 and topical cidofovir.