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Preparation of pooled cryoprecipitate for treatment of hemophilia A in a home care program. Sensory epithelia from normal rat utricles and those cultured with and without neomycin treatment were assayed for the presence of growth factor receptor mRNAs by RT-PCR (reverse transcriptase-polymerase chain reaction).

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Evaluation of the proportional hazards assumption is essential since its violation raises questions regarding the validity of Cox model results which, if unrecognized, could result in the publication of erroneous scientific findings. We also estimated total body water (TBW), extracellular fluid volume, lean body mass, liver volume, metabolic rate, and body-surface area. Ethanol sclerotherapy for the management of craniofacial venous malformations: the interim results. The crystal phase of the product was determined by the concentration of ascorbic acid, whereas its final structure was controlled by the ultrasonic irradiation time and the concentration of beta-CD.

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HIV and the brain: evidence of early involvement and progressive damage. In vivo and in vitro methylation of lysine residues of Euglena gracilis histone H1. The technique is not yet robust enough to replace the established techniques of helium dilution or plethysmography. This situation requires early surgical intervention to avoid visual loss or ophthalmoplegia. Production and characterization of monoclonal antibodies to Mycobacterium tuberculosis, M.

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Transient thyrotoxicosis and persistent hypothyroidism due to acute autoimmune thyroiditis after interleukin-2 and interferon-alpha therapy for metastatic carcinoma: a case report. The ability to bind amylase may confer a survival advantage on oral bacteria which inhabit hosts that consume diets containing starch. We discuss the potential for computer-aided mathematical modeling of biological systems in medical research with examples from some of the major therapeutic areas: cancer, cardiovascular, diabetic and neurodegenerative medicine. This view has been recently complicated by the finding that PI3Ks can also be involved in protein-protein interactions and affect signaling independently of their kinase activity. Sublethal irradiation and syngeneic bone marrow transplant prolong thyroid xenograft survival.

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The Turnbull-Cutait pull-through technique involved full mobilization of the rectum, complete eversion of the anorectal stump and pull-through of the colon, the excess of which was resected in the second stage of the operation, followed by suture of the colonic and rectal mucosa. Postoperative evaluation included contrast imaging 3 weeks after surgery, urethroscopy 4 months after surgery, uroflowmetry, and American Urological Association symptom score assessment.

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Mapping of transgene insertion points indicates that multiple independent mutants arose from integration at distinct sites within the UPRT gene, suggesting that nonhomologous integration is sufficiently random to permit tagging of the entire parasite genome in a single transformation. Here, we show that tdo mRNA is expressed in various nervous tissues, including the hippocampus, cerebellum, striatum and brainstem. Simulation highlighted that, when all other factors are equal, the species with the highest PO effect will have the highest capture rate and therefore return more accurate population estimates.

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Babinski sign on ICU admission is associated with poor prognosis. To describe recent developments in the area of biologic skin substitutes. rasC- cells also exhibit defects in their responses to both the increasing and decreasing temporal gradients of cAMP in the front and the back of a wave. A high-precision fraction collector for capillary electrophoresis has been developed.

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Such a regulatory mechanism of differential chemokine expression could critically influence the site-specific recruitment of distinct subsets of leukocytes to sites of inflammation and injury. All patients were treated initially with adjunctive dexamethasone therapy, suggesting a dexamethasone-associated effect. Controlled limb reperfusion as a new surgical technique to reduce postischemic syndrome. During isovolumetric contraction the posterior wall moved basally and posteriorly, while the septal wall moved apically and anteriorly. Unlike rats treated with 6-OHDA, this response to ipsilateral stimulation was also reduced.

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The focus of the research was on inpatients and prescriptions dispensed by mental health pharmacists. The electric field within metal-insulator (organic)-metal (MIM) cross-bar junctions created by surface plasmon-polaritons excited on the metal surface allows sensitive measurement of molecular optical properties. Further prospective studies are warranted to address this issue.

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The interaction of amino acid residues with polyribonucleotides was characterized by measurements of melting temperatures (tm) for poly(A).poly(U) and poly(I).poly(C) as functions of the concentrations of various amino acid amides. Study of genetic determination of base clinical components of metabolic syndrome Sleep-wake parameters and the spontaneous unit activity in the lateral geniculate nucleus (LGN) were then chronically recorded during one month after the lesions.

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We used water-soluble styryl pyridinium dyes that fluoresce at the membrane-water interface to study vesicle traffic in endothelial cells. Transient hypothyroidism following administration of roentgen contrast media to the newborn and infants Ten children with Down syndrome, 13 to 29 months of age, participated. The clinical disease activity index correlated significantly with pathologic changes in both the acute and chronic phases of the disease.

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The potency of bovine PPD tuberculins in guinea-pigs and in tuberculous cattle. Knowing and applying the basic management functions of planning, organizing, staffing, directing, and controlling, as well as their permutations and combinations, are vital to effective delivery of public health services.

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Consequently, it was concluded that enhancement of inhibition was one of the features of the kindled hippocampus. Thus, we conclude that PMN-density and CD10 expression change during severe bacterial infection, and that the measurement of PMN-subpopulations may be used to complement the clinical assessment of the severity of infections. Protease-catalyzed incorporation of 18O into peptide fragments and its application for protein sequencing by electrospray and matrix-assisted laser desorption/ionization mass spectrometry. In order to determine changes in oxygenation at clinically relevant tumor temperatures, experimental tumors in rats underwent localized hyperthermia at either 40, 41.8 degrees C or 43 degrees C for 1 h using water-filtered infrared-A irradiation. The definition of critical quality attributes of Chinese materia medica ( CMM) was put forward based on the top-level design concept.

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It is also suggested that magnet waving and external chest wall stimulation in patients with Omni-Ectocor and Starr--Edwards pacemakers require further study and that electrocardiograms recorded from patients in whom they have been implanted have to be analyzed taking into consideration that these pacemakers have features common to both, QRS-triggered (VVT), and QRS-inhibited (VVI) pacemakers. We report a 54-year-old female with allergic contact dermatitis from 2-(2-hydroxy-5-methylphenyl)benzotriazole (Tinuvin P) in a spandex tape sewn into underwear.

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A 7-1/2-year retrospective study was undertaken to substantiate or disprove this claim. Body mass index and risk of surgical site infection following spine surgery: a meta-analysis. These results confirm DKK1 as an important therapeutic target in myeloma and provide the rationale for clinical evaluation of BHQ880 to improve bone disease and to inhibit MM growth. Detection of M paratuberculosis infection in young cattle continues to be difficult using current tests. Positron emission tomography and single photon emission computed tomography.

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7-Dehydrocholesterol accumulates in fetuses affected by the Smith-Lemli-Opitz syndrome as a result of a deficit in the ultimate step of cholesterol synthesis catalyzed by Delta7 reductase. Although renin-angiotensin system (RAS) inhibitors have little demonstrable effect on mortality in patients with heart failure and preserved ejection fraction (HF-PEF), some trials have suggested a benefit with regard to reduction in HF hospitalization. The pineal is further characterized by the presence of a small number of glial cells and myelinated nerve fibers. Atrial natriuretic peptide in pregnancy: response to oral sodium supplementation.

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GFA protein-positive cells were present in all tumors not associated with tuberous sclerosis. Surgical therapy may be beneficial in some patients with medically intractable epilepsy. Molecular mechanize and clinical feature of azole-resistant Candida albicans strains and new strategy of treatment A variety of MR-compatible biopsy needles and a prototype coaxial drill system, powered either by hand or an optional motor, are presently available for sampling skeletal lesions. The products could be visualised separately by agarose gel electrophoresis/ethidium bromide staining.

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The Red Cross, in concert with family planning organizations and religious groups, are working together to educate and help care for people with AIDS. After digestion of genomic DNAs of both L-cells and mouse brain, which contains beta- and gamma-actins, by Eco RI, Hind III, Bam HI and Sal I, obtained fragments were investigated by Southern blott analysis using 32P -labeled probe constructed from PA1 which carries a full length copy of chicken beta-actin mRNA. Ad 7 had a modified polypeptide composition with a major 43K component.

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Within 2 weeks of intravitreal injection, vision improved from counting fingers at 1 m to 20/50 OS, and from counting fingers at 4 m to 20/40 OD. Antigonadotropic and gonadotropic compounds which differ from the indoles above mentioned could be located with the same methods.

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The mechanism of RTA induced by chemotherapy in cancer patients has not yet been clearly elucidated. The transient receptor potential vanilloid 1 (TRPV1) channel is critical for spinal afferent signaling of burning pain throughout the body. However, this application requires a design of WSN taking into account the network lifetime and the shadowing effect generated by the trees in the forest environment. Attempts to transplant the tumor to the anterior chamber of two other species of fish and to frogs, were unsuccessful.

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GATA1 and GATA2 recognize specific regulatory GATA motifs, and their expression levels change dynamically during erythroid differentiation, leading to diversified gene expression during erythropoiesis. The Development Model for Integrated care (DMIC) describes nine clusters containing in total 89 elements that contribute to the integration of care. Examination of hDcp1a and hDcp1b proteins by electrophoresis in mitotic cell extracts showed a pronounced slower migrating band, which was caused by hyper-phosphorylation of the protein.

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Results and consequences of radiotherapy for malignant bladder tumors Use of ticarcillin/clavulanate (Timentin) in the management of pediatric infections. Our study confirms that a time-limited problem-solving family therapy approach is of use in these ethnic groups. This article evaluates the association of prehypertension with incident Type 2 diabetes in the San Antonio Heart study.

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The contribution of intrapulmonary chemoreceptors (IPC) to the respiratory response, following a step decrease in PICO2 was assessed in anesthetized and unidirectionally ventilated chickens. Reproduction was inversely related to individual size and light in Syagrus petraea, probably because this clonal palm invests heavily in sexual reproduction during its younger stages and clonal activity in older stages and may be adapted to the low-light conditions of the woodland understory. Interleukin-6 concentration changes in plasma and saliva in bisphosphonate-related osteonecrosis of the jaws. Attenuation of postischemic brain hypoperfusion and reperfusion injury by the cyclooxygenase-lipoxygenase inhibitor BW755C.

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Rice bran oil and its main components (unsaturated fatty acids, triterpene alcohols, phytosterols, tocotrienols, alpha-tocopherol) have demonstrated an ability to improve the plasma lipid pattern of rodents, rabbits, non-human primates and humans, reducing total plasma cholesterol and triglyceride concentration and increasing the high density lipoprotein cholesterol level. The correlation between p53 tumor suppressor gene mutations and the presence of high-risk human papillomavirus (HPV) DNA with the in vitro radiosensitivity of gynecological malignancies was studied in 26 cell lines derived from gynecological cancers of 23 patients. Subordination of the fast-relaxing degree of freedom in the center manifold of the Belousov-Zhabotinsky system. Patients were followed prospectively for technical success, complications, catheter patency, and long-term outcome. However, the results of this meta-analysis should be cautiously interpreted due to the heterogeneity of the studies, inadequate study designs, obsolete therapy and high rate of early treatment discontinuation due to HAI technical failures or hepato-biliary toxicity.

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Sprouting angiogenesis is a key process driving blood vessel growth in ischemic tissues and an important drug target in a number of diseases, including wet macular degeneration and wound healing. Downregulation of TIA-1-enhanced mitochondrial elongation, whereas ectopic expression of TIA-1 resulted in mitochondria fragmentation. MMN magnitude (peak amplitude and area) was significantly larger in the children.

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and remained unchanged during the whole study period of 35 days. Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. Motives to drink or not to drink: longitudinal relations among personality, motives, and alcohol use across adolescence and early adulthood. On the other hand, the sera of monkeys of the Macacus cynomolgos species actively ill with experimental Type III pneumonia have been shown to react in precipitation tests with the C substance. Long-term graft survival is improved in cadaveric renal retransplantation by flow cytometric crossmatching.

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Randomized study with the pineal hormone melatonin versus supportive care alone in advanced nonsmall cell lung cancer resistant to a first-line chemotherapy containing cisplatin. Carbamazepine-induced upregulation of adenosine A1-receptors in astrocyte cultures affects coupling to the phosphoinositol signaling pathway. The study results indicate that Regibloc is at least as effective as, or superior to, Macaine in achieving adequate akinesia. These data may suggest that glucose could be heterogeneously incorporated into the endothelial cells of the cerebral microvessels, and therefore morphological and physiological differences may be present among the endothelial cells. Additional similarities in subunit molecular weights, isoelectric points, and the morphologies of the two protein complexes as determined by electron microscopy support identification of chromobindin A as an adrenal medullary form of CCT.

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We investigated alterations in the HDL proteome in CHF patients. Platelet lysosomal enzymes are normal in myeloproliferative disorders. In average, with the Argon beam coagulator time procedure was respectively 2.7 and 5.4 minutes shorter than monopolar electrocoagulator and Holmio laser. The normal middle ear reflex thresholds towards white noise and acoustic clicks in young adults.

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The approach taken affects agency efficiency as well as the flow of private donations. A descriptive overview of the evaluation research design for a multi-site, community based, healthcare quality improvement initiative is provided. The water content of traumatized and non-traumatized skin was determined. DNA sequence of a small, unidentified plasmid isolated from a Haemophilus somnus strain: short communication. Performance of temporary epicardial stainless steel wire electrodes used to treat atrial fibrillation: a study in patients following open heart surgery.

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The effect of histamine was revealed in the rapidity of the extrusion of zymogen granules and the dilatation of cisterns of granular cytoplasmatic reticulum. In 18 countries at 149 hospitals, 4809 patients undergoing elective or urgent stent implantation were randomly assigned a bolus and infusion of tirofiban or abciximab. The decrease with time can be described by an effective half-life of 3.5 yr caused by a fraction of the 137Cs in the soil becoming unavailable for green grazing plants with time. Possible role of herpes simplex virus in the origin of Posner-Schlossman syndrome. Influence of renal lipoxygenase activity on the renal vascular response to arachidonic acid.

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Antigenicity and immunogenicity of the C-terminal peptide of human thyroglobulin. Here we report the results of a comparative proteomic analysis performed on neonatal (Postnatal day 3) versus adult (Postnatal day 30) AGs, searching for proteins with a relative higher abundance at each age. The thymus plays the major role in the development of self-tolerance, and initial work in the late 1960s indicated that the thymus also plays a critical role in the induction of acquired tolerance to exogenous antigens.

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We study hydrated model membranes, consisting of stacked bilayers of 1,2-dioleoyl-sn-glycero-3-phosphocholine lipids, using terahertz time-domain spectroscopy and infrared spectroscopy. The incorporation of several industrial wastes in ceramic matrixes had been attempted as an effective low expense technique for the fixation of metallic species in usable products or simply to reduce the residue volume for further disposal. The cytosolic subunit p67phox contains an NADPH-binding site that participates in catalysis by the leukocyte NADPH oxidase.

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The composite film was characterized by some analytical instruments to ensure its structure and good dispersion of the MWNTs in the composites. This in turn increases the intracranial pressure inside the skull resulting in progressive enlargement of the head.

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Loan applications in adult patients with congenital heart disease: a French study. The INTERMACS identified 9,808 adult patients from 144 institutions receiving a primary HMII implant between April 2008 and June 30, 2014. These results will enable us to study the electrophysiological properties of dispersed neurons that receive identified baroreceptor synaptic terminals.

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Four hours after dexamethasone treatment, plasma PAI-1 levels were increased approximately twofold over levels measured in animals treated with the diluent alone. The effect of various parameters, such as the type of polymeric matrix, the type of surfactant used for microcapsules preparation and the addition of Pistacia lentiscus resin in the core, on the characteristics of the produced microcapsules and the release rate of alkannin were investigated experimentally.

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How to Improve the Survival of Transplanted Mesenchymal Stem Cell in Ischemic Heart? The purpose of this in vitro investigation was to determine whether the number or pattern of placement of positional screws affected their ability to resist vertical loads resembling mastication. Current indications and results of pulmonary decortication for nontuberculous chronic empyema In this provocation control cross-over trial of 24 patients with dermatitis with a known contact allergy to gold, the patients were randomized into two groups where one was topically provoked to gold (15 mg GSTS) and one to the control.

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This was followed by the detection of HDGF expression in fibroblasts cultured in vitro and fibroblasts exposed to serum. A bound phosphate anion completes the iron co-ordination shell of FbpA and kinetic studies demonstrate that the anion plays a critical role in iron binding and release in vitro. Yet, the toxicity of manganese presents a major limitation for employing MEMRI in behavioral paradigms.