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The operations included 16 posterior lumbar interbody fusion (PLIF), 7 posterolateral fusion (PLF), and 2 combined PLIF and PLF (PLIF/PLF). The discussion is based on how the trials took place and what can ultimately be learned from the outcomes of the studies. After 3 years, prospective evaluation was completed and monitoring of ovarian function was performed as usual in our institution (1x/year). Ubiquitin, cellular inclusions and their role in neurodegeneration. A discussion with a staff member revealed her vivid memory of the arrival of the community-based family planning worker in her village 10 years earlier, before she was married.

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Our large-scale case-cohort study provides some evidence for a possible interaction of TCF7L2 variants and an incretin-specific genetic risk score with coffee consumption in relation to the risk of type 2 diabetes. The principal focus of the work is the design of chemical arrays during lead optimization, and the study hence considers not only biological activity but also important drug properties such as metabolic stability, permeability, and lipophilicity.

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Conversely, TNF-alpha, in the same conditions, strongly stimulated membrane ICAM-1 expression and the shedding of the soluble form. The variant genotypes of CYP11B2, ACE and eNOS were identified by PCR assays. Epidural compression was diagnosed by magnetic resonance imaging (MRI) scans. These ocular findings probably represent a new disease of unknown etiology. Structure and function of the LDL-receptor in genetic disorder--familial hypercholesterolemia is described as well as the structure of receptor coding gene.

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There are study findings to suggest that as more data are available, specific IUDs can be prescribed for defined ranges of uterine cavity length. In the absence of visual cues, deflection of the vibrissae by the sudden motion of the dispaly provided two of the four animals with sufficient information to initiate and guide their movements without changes in response latency. Radiation retinopathy: electron microscopy of retina and optic nerve. Nickel-induced erythrocytosis: efficacies of nickel compounds and susceptibilities of rat strains.

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This may be a direct effect of cortisol on the testis or via the gonadotropin secretion by the pituitary. Two of these sites bound factors common to the retinoblastoma control element and these proteins were induced upon terminal differentiation of the liver. To assess the differences between commercial and pharmacy-compounded preparations of baclofen for intrathecal administration. Evaluation of functional periodicity of the pituitary gland by harmonic analysis.--IV) Circadian prolactin secretion in women with breast cancer A large part of the JSS is devoted to discussing the diagnosis of abdominal obesity.

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To characterize atrazine-degrading potential of bacterial communities enriched from agrochemical factory soil by analysing diversity and organization of catabolic genes. Given the conservative nature of regulatory genes and the homology of vertebral elements, the presence of fusion in stem gnathostomes implies that the mechanism of fusion in mouse and chick models can be extrapolated to extant chondrichthyans (testable) and accounts for the phenotypic similarity across gnathostomes.

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The fine structure of the basal lamina in the lizard pituitary gland. Microcolpohysteroscopy is a useful adjunct to colposcopy and is also of value in locating the epicenter of lesions and is diagnosing HPV infection.

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Oncostatin M stimulates collagen and glycosaminoglycan production by cultured normal dermal fibroblasts: insensitivity of sclerodermal and keloidal fibroblasts. While most intraosseous SOTs occur as solitary lesions, a multicentric variant has also been previously described.

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A total of 72 renal dynamic scintigraphic studies were performed within 2-weeks of renal transplantation in 42 patients. Florivore impacts on plant reproductive success and pollinator mortality in an obligate pollination mutualism. To test the influence of suspended solids on contaminant assimilation, C.

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Seventy-two patients had malignant obstructive disease, 5 patients had common bile duct stones, 4 patients had bile duct injuries, and 3 patients had inflammatory processes resulting in common bile duct obstruction. It was often unclear whether the pump was in place and operational during the intraoperative period. Spectral degree of polarization uniformity for polarization-sensitive OCT. There was in decrease in amplitude of FCERGs with age, which is a agreement with literature data. Does acetyl salicylic acid (ASA) have a role in the prevention of venous thromboembolism?

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We show that the partitioning of within-condition to between-condition variation cannot reasonably be ignored, whether in single-organism RNA-Seq or in Meta-RNA-Seq experiments, and further find that commonly-used RNA-Seq analysis tools, as described in the literature, do not enforce the constraint that the sum of relative expression levels must be one, and thus report expression levels that are systematically distorted. Here we show that efficient multiubiquitination needed for proteasomal targeting of a model substrate requires an additional conjugation factor, named E4. or intrahypothalamically implanted estradiol and a simultaneous rise of the estrogen and gonadotrophin levels in the blood were revealed during the last days preceding the onset of puberty.

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It is known that augmentation of the hypoxanthine plasma, cerebrospinal fluid, and urine levels reflects tissue hypoxia. Polyclonal antisera generated against Nef synthetic peptides blocked proliferation.

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thuringiensis oppB gene reproduced the effect of the mini-Tn10 insertions (i.e. Nanotechnology-related environment, health, and safety research: examining the national strategy.

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The ethnic focus group in this study was Thai and Chinese who reside in Bangkok, Thailand. We reviewed the medical records and angiograms for patients who underwent endovascular treatment for CCAs at three academic medical centers. Real-life chromoendoscopy for neoplasia detection and characterisation in long-standing IBD.

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Bacterial internalization by enterocytes was quantified using the gentamicin protection assay. GPCRs regulate a remarkable diversity of biological functions, and are thus often targeted for drug therapies. Although further follow-up (including late angiography) will be necessary, no clinical events have occurred to date in the 192Ir group to suggest major untoward effects of vascular radiotherapy. This new approach, called the competitor-introduced Ggamma recruitment system, will be useful for efficient discovery of rare valuable candidates hidden among excess ordinary ones.

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The partial pressure of tissue oxygen (pO2) was measured in rat somatosensory cortex during periodic electrical forepaw stimulation of either 1 min or 4 s in duration, and correlated with simultaneous laser Doppler flowmetry. The illness did not develop if Pyrithione was applied during the first 15 days after the infection. The cytotoxic activity of 1-3 was evaluated and showed no activity against the assayed human cancer cell lines. In eukaryotes cell division is accompanied by phosphorylation of histone H3 at serine 10.

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The two tyrosine kinases share identical SH2 and kinase domains but differ in their NH2-terminal amino acid sequence. Escherichia coli bacteremia exacerbates cyclosporine-induced renal vasoconstriction. We aimed to investigate the phenanthrene degradation characteristics and possible phenanthrene degradation pathways of Rhizobium petrolearium SL-1. The study comprised 18 women with early-onset (gestational weeks 24-32) and 19 women with late-onset (gestational weeks 35-42) preeclampsia.

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OCT may offer superior imaging of SF compared to fluoroscopy and IVUS and might prove useful for the detailed assessment and tailored treatment of this rare complication. Monolithic columns have been successfully used with steep gradient and high flow rates for the direct analysis of a candidate pharmaceutical compound in human plasma.

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Normal microflora and dysbiosis at different levels of the upper respiratory tract in healthy children and pneumonia patients High reliability of cardiovascular responses may therefore constitute a risk for hypertension. After a booster injection of the vaccine at the 10th week, there was a significantly greater HA-antibody response and a greater amount of 2-ME-resistant antibody was formed. Lateral node dissection can neither reduce recurrence nor improve survival in the current study, which is not recommended to be a routine procedure in rectal cancer surgery. Efficacy of a simple intraoperative transfusion algorithm for nonerythrocyte component utilization after cardiopulmonary bypass.

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These results provide strong evidence that the presence of a hydroxyl group at the 24 position of vitamin D3 is not required for the maintenance of calcium-phosphate homeostasis during growth and in the development and mineralization of bone. There is difficulty in establishing homology between their tooth components or in summarizing their tooth shapes, yet both carnivorans and rodents possess a comparable spectrum of dietary specializations from animals to plants. This study was conducted at three major hospitals/laboratory of central, eastern and western Nepal during November 2008 through July 2009. Subjects were interviewed and diagnosed by a trained psychiatrist, 370 microsatellite markers were genotyped and the program FEstim was used for homozygosity mapping.

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The molecular basis of torpor induction is unknown, however starved mice overexpressing the metabolic hormone fibroblast growth factor 21 (FGF21) promote fat utilization, reduce body temperature, and readily enter torpor-all hallmarks of mammalian hibernation. The progression from normal colonic mucosa to invasive adenocarcinoma of the colon with lymph-node metastases was documented in Sprague-Dawley rats receiving 30 mg of N-methyl-N-nitrosourea via intrarectal injections.

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Statistical analyses were applied to analyze a tendency of AK cases. Transports of most essential neutral amino acids interacted with each other, as did neutral amino acids with low molecular weights. The person to whom he refers to as important in his life is his mother, who remains noninvolved. In recent years, with widespread laparoscopic cholecystectomy and liver transplantation, complications involving the biliary system are increasing. Differences between groups were measured by analysis of covariance.

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Cumulative odds ratios (OR) were calculated to measure differences in recovery between educational levels and income groups with adjustments for case mix. Residential fires caused at least 67 deaths and 2,500 non-fatal injuries to children aged 0-16 in the United Kingdom in 1998.

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Morphological similarities between the mesenchymal tumour cells and the superficial mesothelial cells, which are always separated from the true tumour tissue by an intact basement membrane, were not observed. Oral treatment for jaundice using immobilized bilirubin oxidase. Cells from both tumours treated in vitro with Adriamycin immediately after excision were slightly more resistant than the cells maintained in vitro.

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Prostaglandin endoperoxide synthetase and the activation of benzo(a)pyrene to reactive metabolites in vivo in guinea pigs. Involvement of the dorsomedial hypothalamus and the nucleus tractus solitarii in chronic cardiovascular changes associated with anxiety in rats.

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Midluteal serum progesterone concentration does not predict the outcome of pregnancy in women with unexplained recurrent miscarriage. In contrast, depletion of Plzf suppressed the MLL-fusion-induced leukemic transformation of HSCs in vitro and in vivo.

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However, the derivation of a simple, evidence based prediction rule to assist patient management has not yet been described. In this study population, heterogeneous defects in insulin secretion were demonstrated, while defects in insulin sensitivity were not evident. For example, a formulation of a drug with low solubility (LS) and/or low permeability (LP) characteristics might provide the required systemic concentrations when administered with food, but not if administered on an empty stomach. Testosterone propionate has been shown repeatedly to be effective in the treatment of vulvar lichen sclerosus, yet studies of androgens in serum of women with untreated vulvar lichen sclerosus suggested an abnormal activity of 5-alpha reductase in these patients.

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Adipocyte insulin-binding species: the size and subunit composition of the larger binding species. Delayed left ventricle posterior wall rupture following mitral replacement detected by multislice CT-scan. Pretreatment and posttreatment electromyographic output and strength were measured. We study proton diffusion in amorphous SiO2 from the atomic scale to the long-range percolative regime. Further it is evident that in some fetal diseases, such as intrauterine growth restriction, fetal condition may change acutely and accordingly best outcome is achieved by much more frequent testing.

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There have been many reports describing the complications of retained ureteral stents following stone treatment. Neuronal dynamics in the visual corticothalamic pathway revealed through binocular rivalry.

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Meanwhile, hydrogen production under light/dark cycle was evaluated. What are the current recommended guidelines concerning the use of contact lenses in the chemical industry?

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Photosynthetic water oxidation in cytochrome b(559) mutants containing a disrupted heme-binding pocket. A new model of an arteriovenous fistula in chronic kidney disease in the mouse: beneficial effects of upregulated heme oxygenase-1. In this study, we set out to study the role of GATA6 expression on proliferation and apoptosis of pancreatic cancer cells and the role of reactive oxygen species. In addition, similar accumulation of PPL at cellular boundaries was found in epithelial cells around renal tubules upon ureteral obstruction. The surgical management implications of diffuse intimal thickening are discussed.

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Method for the determination of the total fluorine content of whole blood, serum/plasma, and other biological samples. Secondary glaucomas were diagnosed at the same examination or after the primary diagnosis was made, and included those associated with cataract formation, lens luxation, cataract surgery, uveitis of unknown cause, hyphema of unknown cause, and intraocular neoplasia.

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Impaired plasma membrane barrier function resulting from a change in the lipid composition appears to cause the increased drug sensitivity of the double mutant strain Deltapdr16,Deltapdr17. The technique is proposed for scanning IR surveillance systems operating in poorly characterized but primarily low-frequency clutter interference. Early clinical pharmacological trials with a new anti-epileptic, milacemide, using pharmaco-EEG and psychometry. The longitudinal and transverse resolutions are 3 m and 9 m respectively.

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Recent developments in the field of polyps of the colon are discussed. We present a case of vaginal evisceration during intraperitoneal chemotherapy for advanced ovarian cancer. Higher emotional distress in female partners of cancer patients: prevalence and patient-partner interdependencies in a 3-year cohort. Computation of the asymptotic null distribution of goodness-of-fit tests for multi-state models.

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Above 2 mmol/l, inactivation occurs but at lower iodoacetamide concentrations there is a relatively slow increase in activity. These data support a mechanism of action for metformin involving antagonism of glucagon, and suggest an approach for the development of antidiabetic drugs. Murine endothelial leukocyte-adhesion molecule 1 is a close structural and functional homologue of the human protein.

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Value of proton spin tomography in the diagnosis of intra-articular pathological disorders of the knee O-acetylated sialic acids of glycoproteins and gangliosides show cell type-specific and developmentally regulated expression in various systems and sometimes reappear as oncofetal antigens.

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Partial purification and characterization of pentalenene synthase. She developed a bilateral visual disturbance at the time of needle puncture during a computed tomography (CT)-guided percutaneous needle lung biopsy in the face down position. To examine associations of adiposity and physical activity with incident LUTS in community-dwelling older men. Establishment of a human embryonic germ cell line and comparison with mouse and human embryonic stem cells.