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Expression and regulation of calcitonin gene-related Peptide receptor in rat placentas. This study has generated important knowledge that is being used to design and test a peer-mentoring intervention on a group of older people with chronic low back pain and volunteer peer mentors. The periodontal examination consisted of plaque index (PI), bleeding index (BI), probing depth (PD), and clinical attachment level (CAL). We have previously demonstrated that cultured human bronchial epithelial cells produce cytokines with potent proinflammatory properties on exposure to several stimuli in vitro, and we have hypothesized that these epithelial cell-derived factors may contribute to the pathogenesis of some inflammatory diseases of the bronchial mucosa, particularly asthma, by promoting the infiltration of granulocytes and T cells and their local activation. Epimysia, perimysia, and subcutaneous connective tissue fail to develop properly.

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The in vivo function of p21 in the context of telomere dysfunction is unknown. An overdenture was planned, and an implant-supported prosthesis was considered for when the patient had finished growing.

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Augmentation of the upper lip with temporalis fascia appears to be safe and effective. Constructing proteins by dovetailing unprotected synthetic peptides: backbone-engineered HIV protease.

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Alcoholism is one of the most prevalent substance dependence disorders in the world. In particular, considerable evidence points to intravenous soybean oil emulsion as a negative factor in the nutritional support of stressed patients.

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Human growth hormone (GH) stimulates AKAP 18 alpha expression and attenuates palmitate-induced suppression of AKAP 18 alpha mRNA level. The aim of the current study was to retrospectively examine introduction of food during the first year in a representative sample of Swedish children. High-dose rapid schedule chemotherapy for disseminated neuroblastoma. The present review summarizes and discusses the biological functions of PDGFs and PDGFRs in developmental processes, mainly as revealed through genetic analysis in mice.

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Endocarditis caused by Blastoschizomyces capitatus and taxonomic review of the genus. Multislice CT angiography of fenestrated endovascular stent grafting for treating abdominal aortic aneurysms: a pictorial review of the 2D/3D visualizations. Of the three methods tested (blood smear, coulter-counter, and Malassez counting chamber), the blood smear proved the most reliable.

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The use of phthalocyanines in conjunction with red light has been shown to inactivate model lipid-enveloped viruses in red cell concentrates. Horses with identical back injuries appear to show similar changes in their back kinematics, as compared to the asymptomatic condition.

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Three different GAL4/E2F-1 mutants that activate transcription, but fail to bind to RB, are not significantly affected by overexpression of RB. Yet we have only a limited understanding of the underlying mechanisms and, consequently, the management of this condition. This burden of rhinitis is associated with impaired sleep, excessive daytime sleepiness, concentration problems, and increased irritability. TBHP exposure disrupted mitochondrial membrane potential and induced apoptosis as evidenced by flow cytometric analyses.

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The preservation of good nutritional status is the guarantee of a better prognosis. The lowest pressure was found in abduction combined with traction. Participants were 88 current male and female smokers with no intention to stop smoking, but who agreed to substitute e-cigarettes for their current cigarettes.

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Therefore, HCHWA appears to be the first genetically determined disease related to the gastroenteropancreatic neuroendocrine system. A full plate for future investigation in the diet-cancer connection. A knowledge of the size distribution pattern of restriction fragments of the genomic DNA makes it possible to calculate the heterogeneity or complexity of the restriction fragment in each size-fraction.

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Increased numbers of multinucleated cells were formed, but unlike normal murine bone marrow cells, they did not form resorption pits. Hypertension treatment and the prevention of coronary heart disease in the elderly. Some tissues are provided to investigators from tissue banks for which tissues have been collected and processed according to standard operating procedures (SOPs) of the tissue bank. Children were exposed to one-third the level of mature adults and underage teens to approximately the same level as young adults.

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These conclusions are consistent with earlier functional studies which failed to detect cAMP-stimulated Cl- channels in cells expressing CFTR delta F508 (refs 16, 17). However, the nature of the vascular calcification has remained poorly understood up to now, owing to the absence of any precise mineralogical examination. Color Doppler imaging of the retrobulbar circulation in age-related macular degeneration. Norovirus infection causes a significant burden of morbidity and (in the developing world) mortality.

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Our knowledge of genetic factors influencing expression of epilepsy has increased enormously in the last 10 years. An explanation for the discrepancy between these results and the results of studies conducted more than 20 years ago, in which mammalian prolactin was highly effective in inducing incubation behavior in chickens, may lie in differences in purity of the prolactin preparations used.

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Analysis of individual populations also reveals signals of association in the Canadian, German and Italian samples. The elbow is the most frequently involved joint in neuropathic arthropathy caused by syringomyelia, followed by the shoulder. The results evidence the usefulness of this measure and the NPI-D for detecting social disinhibition after TBI. Acetic acid bacterial lipids improve cognitive function in dementia model rats. The amplitudes of unit events in Limulus photoreceptors are modulated from an input that resembles the overall response.

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Gene expression and brain plasticity in stroke rehabilitation: a personal memoir of mind-body healing dreams. It has been confirmed that epsilon-aminocaproic acid (EACA), an inhibitor of fibrinolysis, reduced the incidence of fat embolism in the lung of rabbits with experimental bone fractures. In broods hatched asynchronously, sons, which are over-represented in the earlier-laid eggs, were in better condition than daughters, which are over-represented in the later-laid eggs. The extent of this discordance among patients receiving LDL-lowering therapies however is less clear. They were also compared, in both moments, to 37 healthy subjects.

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To establish the feasibility and suitability of peripheral access for different apheresis procedures, undertaken in elective or emergency settings. First detection of group C rotavirus in fecal specimens of children with diarrhea in the United States.

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Augmented left ventricular diastolic nonuniformity contributes to diastolic dysfunction in hypertrophic cardiomyopathy. The prevalence and magnitude of childhood obesity are increasing dramatically.

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Serum was drawn from 925 patients admitted to acute psychiatric in-patient care. Extracorporeal shockwave lithotripsy now forms a permanent part of the conservative therapeutic approach to cholecystolithiasis. Somatic complaints, social withdrawal and poor school performance were also observed. Undernutrition and associated factors among hospitalized patients.

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Human mononuclear phagocytes have the capacity to metabolize arachidonic acid (AA) into prostaglandins (PG) endowed with potent activities in immune responses and inflammatory processes. Significantly lower mitogenic responses of fresh cells co-cultured with Con A-stimulated cells were found when compared with the responses of fresh cells co-cultured with preincubated control cells. In silico tools designed to provide this type of prediction are available.

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The use of risk factors help select those patients in whom a total thyroidectomy would be of benefit. To investigate low-dose/low-dose-rate effects of low-linear energy transfer (LET) ionizing radiation, we used gamma-irradiated cells adapted to grow in a three-dimensional architecture that mimics cell growth in vivo.

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Interestingly, we demonstrated that adenosine, as well as apical FN, significantly enhanced the adherence and invasion of Salmonella typhimurium into cultured epithelial cells. Mensuration data in infant eyes with unilateral congenital cataracts. Low-dose 5-aza therapy may be a general strategy to treat those tumors that are sustained by cells with embryonic stem-like properties.GEO NUMBER FOR THE MICROARRAY DATA: GSE42647.

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There appeared to be no evidence of a defect in peripheral conversion of T4 to T3. Next, the optimal classifier is developed under assumed conditions and its performance is compared to that of an adaptive-type classifier implemented with a probabilistic neural network. Celiac disease is an inflammatory condition of the small intestinal mucosa induced by gluten consumption in genetically susceptible individuals, leading to a spectrum of gastrointestinal presentation. Traditionally formed MIPs (as described here) are stable under ambient conditions for years, take only days to make, and use relatively inexpensive components, with the possible exception of the template in some cases which can be reused after it is removed from the polymer to keep costs down.

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The aim of this study was to identify risk factors for hepatic dysfunction during cytotoxic chemotherapy in Japanese patients with non-small-cell lung cancer (NSCLC). An attempt was also made to study the efficacy of antibiotics, corticosteroids, soft stents and rigid stents. This pattern of localization and regulation is similar to that of Ipl1p homologs in higher eukaryotes, such as the human aurora2 protein. Urogenital, gastrointestinal STS, and Kaposi sarcomas were excluded.

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Sections from postmortem human brain were processed for in situ hybridization histochemistry using a 35S-labelled RNA probe transcribed from a cDNA coding for the human preprotachykinin which contains both substance P and K. Pro-nociceptive role of the activation of mineralocorticoid receptor in the pathogenesis of painful diabetic neuropathy. Our aim was to assess the usefulness of SCOR as a marker for transfusion need in preterm infants.

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Gonadal sex steroids and inhibin modulate gonadotropin secretion via feedback from the gonads, but a neuropeptide that directly inhibits gonadotropin secretion was unknown in vertebrates until 2000 when a hypothalamic dodecapeptide serving this function was discovered in quail. Simultaneously, histological dilatation of pancreatic ducts and destruction of acinus were observed. Based on the sequenced chlamydial genome, considerable progress has been achieved in the understanding of the Chlamydia-host cell interaction, indicating that persistence is an alternate state of the bacteria used by Chlamydia to escape the immune system of the host rather than a general stress response.

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Does assisted reproduction make an impact on the identity and self-image of infertile couples? From the mid-1970s on, a general decline in ideal family size has occurred, and the trend is not greatly affected by the economic stagnation or regression of the 1980s. High incidence of type 2 diabetes and increasing conversion rates from impaired fasting glucose and impaired glucose tolerance to diabetes in Mauritius.

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The clinical behavior of the tumor in childhood is comparable to those of adults. To compare the efficacy of endoscope disinfection using automated and manual systems. Should the practicing interventionalist use manual aspiration systematically in all patients or only in selected patients with an angiographically obvious thrombotic burden? Other genes for which transcripts decline upon exposure of wild-type cells to high light are already lower in the mutant during growth in low light.

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Resistance of the rat to reinfection with Fasciola hepatica and the possible involvement of intestinal eosinophil leucocytes. Although there was no significant correlation between gastric dysmotility and deviation in personality traits in functional dyspepsia patients, these data suggest that brain-gut interactions may play an important role in the symptoms of functional dyspepsia.

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Myelodysplastic syndromes (MDS) are a heterogeneous group of diseases characterized by ineffective hematopoiesis presenting with peripheral cytopenias in combination with a hyperplastic bone marrow. A coadministration of cicletanine (20 mg/kg i.v.) and hydrochlorothiazide, at a maximal effective dose (20 mg/kg i.v.), induced an additional diuretic and saluretic effect.

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Paraoxonase 1 (PON1) inhibits monocyte-to-macrophage differentiation. Adjustment of CCS analyses for clinical variables provided little additional convincing evidence. Evaluation of cell-free tumour DNA and RNA in patients with breast cancer and benign breast disease. The pancreas, however, is spared from clinical evidence of infection, and no rejection was noted when immunosuppression was decreased.

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A second-dimensional electrophoresis in a sodium dodecyl sulfate system led to the migration of the 11 bands, separated by first-dimensional isoelectric focusing, into three distinct groups with apparent molecular weights of 38 000, 32 000 and 26 000, respectively. We reviewed all medical records of residents in Olmsted County with physician-diagnosed SS from 1976 to 1992 to determine whether they had undergone objective tests for keratoconjunctivitis sicca, salivary dysfunction, or serologic abnormality. Total pulse energy ranged between 2,000 and 36,000 millijoules in order to test the extreme range of energy that might be required. Cytokine-induced differentiation of cultured nonadherent macrophages.

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For proof-of-concept, we used TALE or CRISPR/Cas9 nucleases to site-specifically integrate an anti-hepatitis C virus (HCV) shmiRNA into the liver-specific miR-122/hcr locus in hepatoma cells, with the aim to obtain cellular clones that are genetically protected against HCV infection. Readability of 209 pamphlets from professional health organizations, commercial organizations, government agencies, and educational institutions was assessed using three different tests. acetyl-cysteine and of various mineral ions on the enzymic conversion has been studied. Reductive amination of 2-keto-3-methylvalerate to L-isoleucine by a two-enzyme-cascade was achieved by overproduction of endogenous L-alanine dependent transaminase AvtA and heterologous L-alanine dehydrogenase from Bacillus subtilis in recombinant E. Improvements in medicine have significantly prolonged life of chronically ill children and adolescents in the past several decades.

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Impact of switchgrass biochars with supplemental nitrogen on carbon-nitrogen mineralization in highly weathered Coastal Plain Ultisols. Chronic hyponatremia should always be corrected slowly to avoid such osmotic myelinolysis syndromes (OMS).

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Diacetoxyscirpenol as a new anticancer agent to target hypoxia-inducible factor 1. For this group, obtaining both verbal and written agreement from subjects appeared to be the most efficacious procedure to increase compliance. We sought to determine if Mclk1 heterozygosity protects against atherosclerosis and dyslipidemia in these models.

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TiO2-modified CNx nanowires as a Pt electrocatalyst support with high activity and durability for the oxygen reduction reaction. There was a close correspondence between the slow phase velocity of nystagmus and unit activity in the vestibular nuclei under a wide variety of test conditions after flocculectomy.

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Furthermore, multiple tumor suppressor loci are now known to exist, with one to several different loci associated with a given tumor type. Moreover, at 5 min after the administration of an intravenous bolus dose of pindolol to CAM-treated rats, the free concentration of pindolol was lower but the total concentration was higher, compared with the control rats. We analyzed various clinicopathologic factors, which were divided into 3 categories: preoperative, intraoperative, and postoperative.

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Extraneous micro-particles can be partly eliminated from stored blood by filtration. Hepatitis C virus kinetics and host responses associated with disease and outcome of infection in chimpanzees. Since this ELISA can be performed rapidly, only samples which contain sufficient specific material can be selected for electrophoresis and blotting. We propose that the adaxial-abaxial patterning mechanism has been co-opted during evolution to generate diverse organ morphologies.

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We evaluated DNA synthesis in peripheral blood lymphocytes (PBL) from 33 RA patients on oral MTX (7.5-15 mg/wk) and in 30 healthy controls by flow cytometric cell cycle analysis (CCA). The evaluation of coronary artery disease (CAD) in patients undergoing vascular surgery can provide information with respect to perioperative and long-term risk for CAD-related events. These findings justify the use of FMD as an outcome measure for short- and medium-term assessment of pharmacological interventions.