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The role of vitamin D3 in the defective phosphate transport was investigated in three experiments by treatment of mutant mice with the natural hormonal form of vitamin D3, 1,25-dihydroxyvitamin D3, or its potent synthetic analog, 1 alpha-hydroxyvitamin D3. Biodistribution studies of these Ag-associated vehicles showed that the liver, spleen, and lung were the major organs responsible to scavenge these carriers, suggesting that the monocyte-macrophage system was involved in the Ag presentation for CTL.

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The study of innate drug resistance of human hepatocellular carcinoma Bel7402 cell line. The analysis of secondary structure of ALG2 protein allowed to reveal sites capable for forming alpha-helices with heptade periodicity.

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Focal lesions on bone scan located about the knee in the lateral aspect of the distal femur or lateral aspect of the proximal tibia in the metaphyseal region of these bones are not compatible with the characteristic scintigraphic features of stress fracture. This potentiation is mediated by 2 mechanisms: inhibition of adenylate cyclase and activation of phosphatidylinositol 3 (PI 3)-kinase. Aplysia showed modest conditioning that grew across the post-test period.

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Using a unique panel data set of state-to-state outward and return migration flows between Mexico and the United States from 1995 to 2012, this study is the first to analyze Mexico-U.S. In order to predict disordered binding regions, we seek to identify segments that are in disordered regions, cannot form enough favorable intrachain interactions to fold on their own, and are likely to gain stabilizing energy by interacting with a globular protein partner. The aim of this program is to improve the standard of heart failure care in the hospital and outpatient settings and to increase the use of evidence-based therapeutic strategies to prolong life in the large number of heart failure patients hospitalized each year. To the best of our knowledge, there is no such systematic study reported so far which embraces variation of charge transport characteristics with varying wall thickness of conjugated polymer nanotubes involving both I-V and R-T measurements supplementing each other, which being the main focus of this communication.

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Vitamin D supplementation and monitoring in multiple sclerosis: who, when and wherefore. We analyzed liver samples of common eider (Somateria mollissima) for NODLN by enzyme-linked immunosorbent assay (ELISA) and liquid chromatography/mass spectrometry (LC-MS). The contents being the small bowel and the colon, they were reduced.

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In addition primary leukemic cells as well as several erythroleukemic and nonerythroid cell lines were analyzed for GATA factor expression. The effect of two types of cross-linking on some mechanical properties of collagen. These observations suggest that growth cones would be unresponsive to the multiple adhesive cues such as would be presented by oriented extracellular matrix or certain axon fascicle structures, but could be guided by isolated adhesive tracks. (4) The time of onset of cerebro-vascular accident may be related to the hemodynamic and hormonal change.

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Fluorescence-Enhanced Sensing of Hypochlorous Acid Based on 2-Pyridylthiazole Unit. Diagnostic value of diffusion-weighted imaging (DWI) for the assessment of the small bowel in patients with inflammatory bowel disease. Immunoreactivity of endothelins and endothelin receptor in the stria vascularis of the mouse cochlea. Patients who are discharged home experience better outcomes in both pre- and post-transplant survival. Like patients with hypertension and those with hypertrophic cardiomyopathy, patients with CAD display abnormalities of LV diastolic performance under basal conditions in the absence of ischemia.

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Since the power spectrum of HR fluctuations measures the dynamic nervous control of HR, it can be used to quantitate a normal control system as opposed to a disturbed or depressed system. The data suggest that the biphasic release of 14C from muscle of trout exposed to 14C-2-methylnaphthalene may be due to differential elimination of parent compound and metabolites. The effect of five common contact lens solutions on the overall diameter and base curve radii of PMMA, siloxane/acrylate and fluorosiloxane/acrylate lenses was studied. Positive correlation between host size and infection was evident only in the winter and spring months with highest levels of infection in the largest fish. In 75 patients with circulatory insufficiency of various degree the diuretic effect of moduretic was studied.

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Patients were asked to record presence or absence of abdominal cramps and other symptoms and to return for follow-up in 7 days. These terms do not appear to have a universal meaning to all researchers. Administration of 5-FU to the pregnant CD rat on day 14 of gestation results in dose-dependent growth retardation and numerous malformations in near-term fetuses, including hindlimb defects and cleft palate. A diluted solution of biotinylated PEG thiols in OH-terminated PEG thiols is used to form a network of sites for the attachment of neutravidin.

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The spicules formed by anionic drug in different species were numerically related to cell sizes. Repigmentation of poliosis after epithelial grafting for vitiligo. In intravenous anaesthesia ketamine microdrip and new analgesics have widened the scope and the anaesthetist today can chose from a biger pool of i.v. The inclusion criteria were comparative studies including patients who underwent pancreatic resection with or without PV-SMV resection. The windmill effect was graded for windmill intensities over a domain of about 1000 to 1.

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Nomograms for aortic root diameters in children using two-dimensional echocardiography. In contrast, rhEpo, either alone or in combination with hydroxyurea, offered no measurable benefit.

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Pretreatment of rats with a lignan-enriched extract of Fructus Schisandrae (FS) caused a moderate enhancement of hepatic GRC in control rats, but the GRC enhancing effect of FS pretreatment on hepatic tissues was greatly exaggerated after CCl4 challenge. It is speculated that GABA and its analogues exert an inhibitory effect on TSH secretion, presumably at the level of the pituitary, and this effect is not mediated by dopamine. Biomechanical overload of the proximal tibial physis due to static varus alignment and excessive body weight has been implicated in the etiology of infantile tibia vara. Exact solutions in the scalar diffraction theory of aberrations. This peptide corresponds to one of the high-molecular-weight peptides found in canine heart tissue.

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Direct comparison of both preparations revealed no differences in bioavailability. Electroencephalographic (EEG) data, recorded bilaterally, showed that differential hemispheric processing interacted with emotion (positive or negative), condition (cognitive or affective), and sex. Xiaoxuming decoction, an ancient traditional Chinese medical prescription for treatment of stroke, has somehow lost its clinical application since Tang Dynasty.

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A key to an understanding of the origin of the MMCs was provided by the finding of disruption of the normal cycling of the complex by a premature cycle whenever morphine was given. Meta-analysis of the efficacy and safety of fluconazole in prophylaxis of fungal infection in very low birth weight infants Verbatim transcripts were analyzed using a constant comparative method, which included coding, memo writing, and ongoing discussion between the two researchers.

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Assessment of dopamine release by in vivo microdialysis in the nucleus accumbens of rats following acute and chronic administration of desipramine. A chemostat system has been developed to model the attachment of oral bacteria, and the subsequent development of plaque film, to acrylic surfaces immersed in steady state cultures.

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Our findings suggest that the 2 small molecules, when used in combination, can potentially be effective therapeutic agents for treating NSCLC, at least in part, by regulating endoplasmic reticulum (ER) chaperone protein GRP78. The effect of the adhesive Histoacryl Blue on the abdominal organs (liver, stomach, intestines, colon, kidneys, bladder, aorta inferior vena cava and skin wounds) of 15 dogs was investigated histologically. Opposite to that 20 down-regulated transcripts were among others related to pseudouridine synthesis, RNA processing, and ribosome biogenesis. Discrimination parameters for cellular polymorphism in dysplasias of the vaginal mucosa To compare the effects of Simvastatin and alpha-tocopherol on sciatic nerve conduction velocity in obese rats.

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All patients are alive and clinically free of localized disease 0.5 to 12 months after salvage radical prostatectomy. Case populations must match the respective disease model: Genotype diversity causes linkage disequilibrium mapping failure in monogenic disorders. Immunohistological screening in the selection of monoclonal antibodies: the use of isotype-specific antiglobulins.

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Dynamics of yolk sac resorption and post-hatching development of the gastrointestinal tract in chickens, ducks and geese. The single tree that we inferred from our dataset showed excellent nodal support for each branch, suggesting that it reflects the true phylogenetic relationships of the species involved.

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Pedal neuroarthropathy in a nondiabetic patient as a result of long-term amiodarone use. A general procedure was devised for the determination of growth factor requirements of heterotrophic bacteria based upon identification of individual nutrients as they are successively depleted from a limited quantity of complex medium. On the contrary, the incorporation of 3-O-methyl glucose, another glucose analog which is not phosphorylated by hexokinase, was not altered by the treatment with pentobarbital. Spinal and cranial motor nerve roots in amyotrophic lateral sclerosis and X-linked recessive bulbospinal muscular atrophy: morphometric and teased-fiber study.

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The method is illustrated using smallpox data for the Andean region at the end of the sixteenth century. The mechanisms involved in the relaxation of the lower oesophageal sphincter induced by distension of the oesophagus and different parts of the stomach, were studied in an anaesthetized porcine model. The study provides sound justification for improved adhesion prevention strategies. Most of the researchers are using it to study protein-protein interactions, but in recent years membrane model systems have also become available and this makes it possible to study protein-membrane interactions as well.

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Atherosclerotic plaque progression is influenced by intraplaque inflammation and extracellular matrix deposition. Retrospective evaluation of clinical and pathological features, as well as diagnostic and treatment protocols of primary vaginal malignancy. A web portal, with risk categorisation of mild, moderate and severe for drug-herb interactions, can assist doctors in clinical decision making. Cell proliferation and cell density of mesenchyme in the maxillary process and adjacent regions during facial development in the chick embryo.

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To study the impact of rising bilateral mastectomy rates among neoadjuvant chemotherapy (NAC) recipients in California. Clinical trials in psychiatry: should protocol deviation censor patient data? UV-A photocatalytic treatment of Legionella pneumophila bacteria contaminated airflows through three-dimensional solid foam structured photocatalytic reactors. Fourteen of these patients had a diagnosis of ulcerative colitis and 5 had Crohn disease.

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Therefore, agents that inhibit apoptosis may function as tumor promoters. To this end, six animals per species were repeatedly presented with both familiar and novel food items, and their behavior was videotaped and analyzed.

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The significance of germ cell test results for some of these drugs and their implication in assessing risk of heritable genetic disease are discussed. Overexpression of the enzyme in chondrocytic cells further enhanced CS biosynthesis but not that of the aggrecan core protein, indicating that the enzyme activity is not saturated in the cells and that aggrecan synthesized in the overexpressing cells is heavier than the native molecule.

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In vitro, Arabidopsis CURT1A proteins oligomerize and induce tubulation of liposomes, implying that CURT1 proteins suffice to induce membrane curvature. The aim of this study was to correlate T-helper type 1 (Th1), Th2, Th17 and Treg transcription factor expressions, in gingival tissues from patients undergoing active periodontal tissue destruction, with bone loss-associated cytokines. A morphological characterization of nephrocalcinosis induced by injected neutral phosphate was made in both female weanling and young adult rats in order to determine the effects of age on the development of this type of phosphate-induced renal calcification. Laparoscopic cholecystectomy should be considered the procedure of choice for elective cholecystectomy. Rectal cancer is one of the most malignant tumors in gastrointestinal tract, while low rectal cancer with locally advanced stage is the most common type in China.

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Tumor diagnosis, anatomic location, clinical features, management, and histopathology. In both human follicular cell cultures and FRTL-5 cells, immunoblotting showed that Tie-2 expression was increased by TSH and agents that increased intracellular cAMP. In this research, the pseudo toxic concentration (CPT) concept model to quantify pH inhibition effect on activated sludge was proposed and compared with other existed models. It remains unclear whether repetitions leading to failure (failure training) or not leading to failure (non-failure training) lead to superior muscular strength gains during resistance exercise.

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There was a higher incidence of airway symptoms associated with Trachlight intubation. The functional acetylcholine-gated ion channel formed with mutant alpha subunits, but not mutant beta subunits, could not be blocked by alpha-BuTX.

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However, the development of graft-vs-host disease (GVHD) in the context of allogeneic HSCT is associated with injurious effects on thymocyte development. The statistical approaches included calculation of appropriate intraclass correlation coefficients, standard errors of measurements, proportions of measurement differences of 5 or less degrees, and significant differences between paired observations.

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Diuretic refractoriness can be a result of elevated intra-abdominal pressure (IAP) in acutely decompensated heart failure. The usual parasite involved is Toxocara canis, its presence in humans leading to encystment of the larvae and an eosinophilic granulomatous reaction. Metal-dielectric (MD)-structures in electron cyclotron resonance ion source (ECRIS) devices (partially) restore the plasma ambipolarity and supply cold electrons to the plasma. Renal excretion of cystathionine and creatinine in humans at different ages. In relation to the first point, we suggest that the post-translational acylation of dystrophin may contribute to its interaction with the plasma membrane.

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Phosphatidylserine exposure and phagocytosis of apoptotic cells. In this paper we present our experience in treating 23 patients with locally invasive papillary thyroid carcinoma with special reference to extrathyroid spread, surgery and postoperative treatment. The effect of critical care medicine credentialing on pulmonary fellowship training. A PubMed search (http://www.ncbi.nlm.nih.gov/PubMed/) was performed and prognostic markers in RCC were reviewed and presented here. Ultrahigh-resolution two-photon optical Ramsey spectroscopy of an atomic fountain.

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While inhibition of rosetting with in vivo-selected lines by D-GalNAc and galactose was consistent with the involvement of the D-galactose/D-GalNAc-specific hepatocyte receptor, preincubation of the tumor cells but not hepatocytes with D-GalNAc inhibited hepatocyte rosetting and D-GalNAc inhibited homotypic tumor cell binding. Similarities in the neural signature for the processing of behaviorally categorized and uncategorized speech sounds. We found that target cells which are resistant to spontaneous cytotoxicity can, indeed, be killed by LDCC, and that there is an inverse relationship between spontaneous cytotoxicity and LDCC, both when unfractionated lymphocytes were tested against different target cells and when fractionated cells were tested against cell lines highly susceptible to spontaneous cytotoxicity.

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Notably, the metabolic alterations in the SnRK2.6 overexpressors were accompanied by amelioration of those physiological processes that require high levels of carbon and energy input, such as plant growth and seed production. Monospecificity of the antibody was confirmed by immunoblot analysis using both total cell lysates and cytoskeletal extracts as antigens. Currently (2009), such a regulation of this kind of exposure is not explicitly included in the Serbian regulating network. Specimens were resin embedded and examined using transmission electron microscopy and x ray microanalysis. Membranes formed of pure lipids were rather inactive targets for this haemolysin.

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These two proteins, which are part of an important signaling pathway to the genome, are found in a diverse array of developmental situations, for example in the formation of the proximal-distal axes in limbs. Embryos (206 controls, 206 biopsied) were transferred to 26 pseudopregnant recipients. The discussion of diverse safety-enhancing interventions is intended to enable clinicians and caregivers to identify individualized care strategies for patients with frontotemporal dementia. The symptom of excessive sleepiness in children and adolescents does not necessarily cause great concern to families and professionals involved in their care. Few reports describe the treatment of dermatologic diseases due to M.

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The lighter fraction (density 1.44 g/ml), containing predominantly keratan sulphate chains, was eluted from DEAE-Sephadex as a single peak with 1.25 M-NaCl and was retarded on Sepharose 2B: this fraction was not able to form aggregates with proteochondroitin sulphate. Electron probe X-ray microanalysis in the scanning microscope was used to determine the elemental composition of muscle fibres from patients with rheumatoid arthritis (RA).

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Transcripts corresponding to epididymal GPX are not detected in a variety of other tissues (liver, spleen, kidney and testis) and appear to be androgen-regulated in the epididymis. The airflow obstruction was evaluated by measurement of airway insufflation pressure (P1) and plasma extravasation by quantification of Evans Blue dye (EBD) in airways. A case of severe defibrination syndrome due to snake (Rhabdophis tigrinus) bite Follow-up magnetic resonance imaging (MRI) at three and eight months showed complete resolution of the intracranial air.

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Finally, attention is given to factors that affect the preparation of high specific activity, high affinity 99mTc-labeled biochemicals. Further prospective studies are required to confirm the validity of these observations. Tissue slice viability was monitored by two standard methods: assay for intracellular potassium and morphological examination at the electron microscopic level.