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In this study, we investigated whether hypoxia-inducible factor-1 (HIF-1) action impacts on tissue remodeling in GO with the aim to identify possible new therapeutic targets. Production and characterization of monoclonal antibodies against human transferrin.

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Third generation selective estrogen receptor modulators: benefits beyond bone. Data derived using the SAGE technology have been used to identify tumor markers for a variety of cancers, including gastrointestinal cancer, lung and thyroid cancer, breast and ovarian cancer, neuroblastoma and glioblastoma, prostate cancer, and renal cell carcinoma. Chromosomal studies revealed a de novo (new) balanced translocation between first and second chromosomes. Modulation of secretion of follicular stimulating hormone in male: role of inhibin and plasma sex hormone Phenylglyoxal modification of Arg-13 in DRPH led to a 14-fold increase in activity.

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This study investigates (1) local tumor control and (2) normal tissue toxicity of pulsed low-dose rate radiotherapy (PLDR) for recurrent lung cancer. However, more than three aspiration cytologic passes appear to yield diminishing returns. Proliferation and survival of BCEC were tested using haemacytometer of Mallasez. DIRECT MICROSCOPIC OBSERVATIONS ON LIVING INTRAOCULAR TRANSPLANTS.

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Three children with Kawasaki disease had liver biopsies because of evidence of hepatic disease. Early radical excision, with preservation of the facial nerve, is advocated. A comparative study of three model comprehensive elementary school health education programs. To identify predictors of unemployment among Australian people living with HIV/AIDS.

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Treatment of infertility in these cases is with artificial homologous insemination. To study and document the epidemiologic and demographic profiles of patients with PHI in the Eastern Province of Saudi Arabia. The values obtained from the bone markers are continuously fluctuating. However, prerequisites for its use are: a) mastery of technique b) full assent of the patient c) psychic guidance of the patient during the whole duration of the intervention and d) balanced pre-, intra- and postoperative substitution of the volume e) overcoming of the established opinion that the spinal anaesthesia has a particular depressing effect on circulation and frequently causes post-spinal headache. Exposure of patients to phthalates from polyvinyl chloride tubes and bags during dialysis.

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Biological markers in noninvasive brain stimulation trials in major depressive disorder: a systematic review. Randomized trial data will be essential in fully assessing whether or not there is a causal effect of antioxidants in reducing the risk of cardiovascular disease.

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Altering gene expression is one of the major effects glucose has on cells. These findings indicate that transforming growth factor beta can regulate cell morphology and growth in a concerted manner possibly via mechanisms that control the actin cytoskeleton.

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Further compounds in this series were subjected to metabolic stability in human liver microsomes (HLM), mouse liver microsomes (MLM), and exhibits promising stability in both. The data are presented on studying the production of antibodies to influenza A (H3N2) virus by lymphoid cells of the amygdaline tonsils and mediastinal lymph nodes in vitro during stimulation of these cells with influenza virus or lipopolysaccharide of typhoid bacteria. The project began in 1978 and by 1982 the resettlement was complete. Whether movement will enable organisms to alleviate thermal stress is central to the biodiversity implications of climate change.

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We have found that the expression of ERK1/2 was decreased with overexpression of miR-155 in normal nucleus pulposus cell. We have recently seen several patients with rubber glove-induced contact urticaria who have had both positive skin prick tests and positive RAST tests to natural latex from the rubber tree (Hevea brasiliensis). Determination of preservative and antimicrobial compounds in fish from Manila Bay, Philippines using ultra high performance liquid chromatography tandem mass spectrometry, and assessment of human dietary exposure. Few studies have addressed this issue among diabetic patients who meet the more stringent, modern National Diabetes Data Group or World Health Organization criteria. High signal-to-noise-ratio electro-optical terahertz imaging system based on an optical demodulating detector array.

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By transmission electron microscopy (TEM) and glancing incidence x-ray diffraction (GIXRD), it was found that the Si QD size decreases with increases in O/Si ratio. Isothermality, Max Temperature of Warmest Month (TempWarmestMonth), Precipitation of Wettest Month (PrecipWettestMonth), Precipitation Seasonality (PrecipSeasonality) and Precipitation of Driest Quarter (PrecipDriestQuarter) were observed to be effective climatic factors in controlling structure and composition of Gmelin larch forests. Most patients with MSs will develop recurrent cholangitis or stent obstruction and require intervention.

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L1 and N-CAM antibodies trigger protein phosphatase activity in growth cone-enriched membranes. Errors in the diagnosis and treatment of Lyme disease in children are common. Lovastatin also stimulates protein kinase B/Akt kinase activity, and Akt-dependent phosphorylation forces p21 in the cytoplasm, where it inhibits Rho-kinases contributing to the suppression of cardiomyocyte hypertrophy. The determination of the dietary requirements for individual essential amino acids and for total protein has been discussed, and it is evident that the data are limited and often contradictory.

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Chronic disruption of MnPO by electrolytic lesion produced pressor deficits to centrally administered ANG II and carbachol but did not change resting arterial pressure. Insights gained from this research will also contribute to the academic field of complementary medicine, specifically aromatherapy, for which the evidence base is extremely limited. Finally, he contends that psychotherapy can contribute positively to enhanced control of violent behavior, even in severely violent and psychotic patients. Among these genes, macrophage capping protein (CAPG), a member of the actin-regulatory protein, was the key gene in a 20-gene network that modulates cell motility by interacting with the cytoskeleton.

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Frequency of echocardiographic complications of dilated cardiomyopathy at a tertiary care hospital. Our results suggest that the same stimuli may have different activity in regulating the paracellular activity in endothelial and epithelial cells. Little research on the value of Health of the Nation Outcome Scales (HoNOS) has occurred in out-patient settings, particularly psychotherapy services. This navigation mechanism is essential for the maintenance of perinuclear MT bundles and for the orientation of peripheral MTs as well as for the apicobasal positioning of MTs. We report the case of a 7-year-old boy who presented with a history of a fall, which was followed by cerebellar signs.

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Cells from many of these patients are deficient in the import of PTS1-containing proteins, but the causes of the protein-import defect in these patients are unknown. Angiotensin II protects primary rat hepatocytes against bile salt-induced apoptosis.

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The detection of Mycobacterium tuberculosis by culture of cerebrospinal fluid (CSF) is unacceptably slow. The pattern of results suggests that whereas the posteroventral caudate-putamen seems to be involved in consolidation of memory in the Morris water maze, it may be involved in memory for procedural aspects of the task in a manner distinct from that of other brain regions such as the hippocampus.

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Two renal biopsies in 3 yr showed lipid deposits in the mesangial cells and indicated a positive correlation between the levels of serum lipids and lipid deposits in glomeruli, which suggested an important role of abnormal lipid metabolism in the progression of glomerular lipidosis. We have also studied the moment of the duplication event relative to the evolution of higher primates by using genomic DNA of a panel of primates.

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Chronic restraint stress has no more stimulatory effects on colonic motility in rats. Nuclear expression of survivin is associated with improved survival in metastatic ovarian carcinoma. In the study described here, polymorphism of the Tn1546-like element enabled the establishment of five groups. The neighborhood environment scale assessed violence, safety, aesthetic quality, walkability, availability of healthy foods, social cohesion, and activities with neighbors. Growth factors, such as TGF-beta1 and IGF-1, have been implicated in cell proliferation and matrix synthesis.

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We analyzed this masking with frozen and formalin-fixed human autopsy brains obtained at various postmortem periods. Presumably, several of the cases must have been coronary heart disease deaths. The rate limiting step in the production of steroids in the testis is the mitochondrial conversion of cholesterol to pregnenolone. DNA from 78 primary tumors was amplified using the polymerase chain reaction (PCR) with primers covering exon 21, followed by constant denaturant gel electrophoresis (CDGE).

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15 subjects (8 men and 7 women, aged 25-56 years, mean 44) examined in the cardiac catheterisation laboratory, who had significant coronary artery disease years after having radiation treatment to the chest and anterior mediastinum. The model donors used in the present study modulate the redox properties only slightly. Tandem organization of StarkB element (22.8 kb) in the maize B chromosome. The correction scheme was observed to reduce both the within-subject and between-subject variability in the calf and thigh muscles of healthy subjects and patient groups in histogram- and region-of-interest-based approaches. The main target of these molecules are a specific compound of fungal membrane, ergosterol.

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Paromomycin sulfate was administered orally in a single dose or 2 divided doses of 40--60 mg/kg, being followed by a purge about 1.5 hours later. This study indicated that some serum cytokines such as sIL-2R, growth factors, and the mixed lymphocyte reaction may be used as parameters for the early detection of the development of GVHD. Family-based association tests and logistic regression conditional on the apolipoprotein E genotype and sex were applied to association study in family-based and case-control datasets, respectively. The band gap properties of graphene quantum dots (GQDs) arise from quantum confinement effects and differ from those in semimetallic graphene sheets.

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While using a hospital-owned wheelchair to descend a 27-m-long, 5.6 degrees slope in an underground tunnel connecting the rehabilitation center to a neighboring acute care facility, the patient had difficulty slowing the wheelchair to negotiate a turn. The availability of transfected CHO cells expressing wild-type recombinant enzyme and mutants in which one of the two active sites has been inactivated by site-directed mutagenesis allowed the properties of each active site on the cell surface and the effect of anchorage and membrane environment to be studied.

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