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Digital flat image detector technique based on cesium iodide and amorphous silicon: experimental studies and initial clinical results The knowledge of the conformational ensemble that a drug target populates may be crucial for the design of small molecules that can differently modulate its function. The problem of signals generated in and received from regions outside the active coil area is discussed in the context of using standard measurement techniques. When used in isolation, CLFAC analyses is therefore not a generally applicable identification technique for yeast species. Antibodies to carcinogen-DNA adducts in mice chronically exposed to polycyclic aromatic hydrocarbons.

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In DEP separation, the DEP force is effective only when it is applied close to the electrodes. The Eph receptor tyrosine kinases and their membrane-bound ephrin ligands control a diverse array of cell-cell interactions in the developing and adult organisms. In addition, both monomeric and dimeric CPAP are required for accurate cell division, suggesting that the temporal dynamics of CPAP homodimerization is tightly regulated during the cell cycle. p34cdc2 homologue is located in nucleoli of the nervous and endocrine systems. Based on features like hypothermia, hypoventilation, and cardiovascular instability occurring in the setting of central hypothyroidism, it should be suspected and managed urgently in order to avert the associated high mortality resulting from treatment delays.

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We investigated the presence of hypersensitivity to iodine in patients with a history of hypersensitivity reactions to RCM. Adult medulloblastoma mimicking Lhermitte-Duclos disease: can diffusion weighted imaging help? Data were analyzed for 123,846 individuals from the CCHS and 13,581 individuals from the CADUMS. Evidence from numerous observational and clinical studies suggest that polyphenolic phytochemicals such as phenolic acids in olive oil, flavonols in tea, chocolate and grapes, and isoflavones in soy products reduce the risk of breast cancer. injection of arsenic trioxide, at the dosage range of 1/4 to 1/40 LD50 into hybrid mice (CBA X C57B1/6J)F1, no induction of dominant lethals in male germ cells was observed.

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sapiens, performed GO term classification and enrichment studies which provide information on the diversity in CCT interactome, in terms of protein classes in the data set. Supernumerary teeth in anthropoid primates and models of tooth development. The diagnosis can only be established by pathologic examination of renal tissue. An antigen of rat parvovirus (Kilham virus) was developed for the diagnosis of viral infection in rat colonies by using hemagglutination inhibition (HAI) test.

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To observe the radiological changes in fracture calluses following administration of a Piper sarmentosum extract during an estrogen-deficient state. Comparison of mesna with forced diuresis to prevent cyclophosphamide induced haemorrhagic cystitis in marrow transplantation: a prospective randomised study. Several mechanisms are responsible for their increased susceptibility, including down-modulation of immune responses that aid in parasite clearance and sequestration of infected erythrocytes in the placenta.

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Improvements in immunotherapeutic treatment strategies may increase the role of surgery for patients with advanced disease. Zuclopenthixol and haloperidol in patients with acute psychotic states. Background components of Ge detectors in Ogoya underground laboratory. The high incidence and debilitating effects of lymphedema must be weighed against the benefits of PMRT. Moreover, postnatally hair follicle morphogenesis and thinning of interfollicular dorsal epidermis were delayed.

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The present observations suggest that organization and sequences of chromosome replication are genetically programmed. The correlation of visual function with posterior retinal structure in severe retinopathy of prematurity. National trials involving lymphatic mapping for melanoma: the Multicenter Selective Lymphadenectomy Trial, the Sunbelt Melanoma Trial, and the Florida Melanoma Trial.

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PAF was added to the medium, and its effects on cell proliferation, fibrinolytic activity, mRNA expression of plasminogens and inhibitors were studied. The concentrations of free serotonin were much lower in lymph (0.1-0.2 ng/ml) than in portal blood (100-200 ng/ml). Thus, this cloned src gene should be ideally suited for inducing reversible transformation and differentiation of mammalian cells in culture.

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To differentiate placental growth factor (PlGF) levels in pregnancies with normal and abnormal glucose challenge test (GCT) results. Cyclooxygenase inhibitor administration prevented the interleukin-1-beta-induced increase in the production of brain prostaglandin E(2) (a cyclooxygenase metabolite) and changes in the expression of brain interleukin-6, interleukin-18, tumor necrosis factor-alpha, and brain-derived neurotrophic factor. Forty patients were randomised to medical or endovascular treatment in equal numbers, and patients were followed up for up to 10 years. The histological proof was provided by lung biopsy which was carried out during a thoracotomy for pleurectomies. These results suggest that the depressed expression of the Klotho-FGFR1 complex in hyperplastic glands underlies the pathogenesis of SHPT and its resistance to extremely high FGF23 levels in uremic patients.

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The left ventricular apex is the optimal site for pediatric pacing: correlation with animal experience. A new activated sludge model is introduced which combines parts of the carbon degradation model concepts as they have been released in the ASM1-model and the ASM3-model, respectively.

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Characterization and heterologous gene expression of a novel esterase from Lactobacillus casei CL96. Pyoderma gangrenosum is a condition that is included among the neutrophilic dermatoses. The sequences of two different proteolytic fragments agreed with the sequence deduced from the cloned gene, and amino-terminal sequence indicated the removal of a 14-residue signal peptide, consistent with the transport of VSP to the cell surface. Anastomotic leakage following low anterior resection (LAR) for rectal cancer is a serious complication that increases morbidity and mortality rates.

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Coordinately, the larval cells extrude from the epithelia by apical constriction of an actomyosin ring and as a consequence die by apoptosis and are removed by circulating haemocytes. Cellular electrophysiological basis of proarrhythmic and antiarrhythmic effects of ischemia-related lipid metabolites Therefore, combination therapy may be the optimal therapeutic option in NIDDM clients manifesting secondary failure to oral agents or insulin resistance. Patient carriers of the 677TT variant and the 677T allele displayed significantly higher Hcy concentration. Therefore, physicians must recognize EQS as a mixed clinical entity indicating careful assessment and specific treatment planning.

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The increase in global coronary flow seen with conventional biventricular pacing is mediated by an increase in the dominant backward expansion wave (BEW). To confirm these data, we did quantitative reverse transcription-PCR and Western blot analyses in a subset of tumor specimens. Standardization with synthetic 22-kDa monomer human growth hormone reduces discrepancies between two monoclonal immunoradiometric assay kits. Clinical experiences with bisphosphonate-associated osteonecrosis of the jaws: analysis of 21 cases.

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Immunohistochemical localization of alpha- and betaA-subunits of inhibin/activin in human normal endocrine cells and related tumors of the digestive system. In addition, the voice loop system is structured around the mission control organization, and therefore directly supports the demands of the domain. When a patient is diagnosed with lung cancer, members of his/her social network may be more likely to engage in smoking cessation efforts.

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We have tested this possibility by comparing the cytotoxicity of drug combinations containing MTX with that of drug combinations containing trimetrexate (TMTX), an antifolate that does not compete with LV for uptake or polyglutamylation. Rotational effects in the continuous vacuum-ultraviolet fluorescence spectrum of H2 associated with spontaneous dissociation. Group sequential methods permit repeated significance testing of relative risks obtained from periodically accumulated data while maintaining the required overall level of significance. Since copper IUDs must be replaced more often than inert devices, there is a risk of increased incidence of pelvic inflammatory disease, reported to occur more frequently after replacement of an IUD.

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Changes of vascular and bone structure occur already within a few months, whereas most of the margination changes are already formed in the early stages of disease and proceed slowly. Crystallization of two cubic forms of soybean trypsin inhibitor E-I, a member of the Bowman-Birk inhibitor family.

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We suggested that Tc-99m DTPA radioaerosol inhalation lung scintigraphy provides an accurate evaluation about stage of lung toxicity and therefore may be a useful tool for the monitoring of AIPT. Intertubular capillary changes in kidney allografts: a morphologic investigation on 61 renal specimens. Organ donor with unclear primary brain tumor, a contraindication for transplantation? Transgenesis in combination with RNAi to specifically inhibit avian enza virus gene expression has been proposed to make chickens resistant to the infection. NO may mediate changes in PDL structure in response to occlusal force.

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The head was then scanned axially on a 64-slice MDCT with 0.4-mm slice thickness and reconstructed into the oblique axial, oblique coronal, and oblique sagittal planes of the cochlea. STUDIES ON THE ANTIGENIC COMPOSITION OF GROUP A HEMOLYTIC STREPTOCOCCI : III. The effect of testosterone on lipid peroxides and antiperoxidative enzymes in normal and orchidectomised animals has been studied. This relaxation was significantly reduced by BU224, a selective I2 imidazoline receptor (IR) blocker, but not by I1 or I3 IR blockers (efaroxan, KU14R respectively). Here we characterize the profile of prostanoids produced by activated HUVECs and analyze the expression and activities of tPGS.

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This is the first intervention study examining the effect of control measures. Microgeographical differences of Plasmodium vivax relapse and re-infection in the Peruvian Amazon. In this paper, we consider the clinical aspects of congenital estrogen deficiency - notably, estrogen resistance and aromatase deficiency - in men and we discuss both well-established and supposed estrogen roles in the human male reproductive function. The frequencies of 5 fetal movements (isolated arm, isolated leg, short trunk, long trunk, and jumping movements) were evaluated.

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Therefore, it was named trypsin-modulating oostatic factor (Aea-TMOF). A significant association between fungal infection of grain and mycotoxin content was observed following natural or artificial infection with the type B trichothecene producer F. In the lamprey locomotor network, analysis on the ion channel, synaptic, and cellular levels has given new insights into the organization of such modulatory systems. Can this hypothesis be supported by measurable alterations in immunoreactivity?

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The frequency and duration of glances at the in-car tasks, total time of eyes-off the road during tasks, speed and lateral displacement of the car were recorded. Microemulsions containing medium-chain glycerides as transdermal delivery systems for hydrophilic and hydrophobic drugs. The 7q11.23 Microduplication Syndrome: A Clinical Report with Review of Literature. These devices, however, cannot provide correct color information because color is construed from the mean value of the observation region, and analysis of color distribution is impossible. The effective orifice area index of at least 0.85 cm2/M2 was considered as lack of prosthesis-patient mismatch.

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Heat capacity changes and hydrophobic interactions in the binding of FK506 and rapamycin to the FK506 binding protein. Evaluation of criteria-based clinical audit in improving quality of obstetric care in a developing country hospital.

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Endometrial study made during the continuous administration of microdoses of 30 micrograms of d-norgestrel Long-term outcome was ascertained in 96 patients who had lumbar discography and subsequently underwent interbody fusion alone, combined fusion, intertransverse fusion or no surgery.

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The aging diver: endothelial biochemistry and its potential implications for cardiovascular health. In addition, transcription of the target gene was regulated by CspA promoter with endogenous RNA polymerase instead of by T7 promoter with exogenous T7 RNA polymerase. The increases in OH8dG were significantly correlated with increases in MDA.

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Despite the opportunity for cervical cancer screening that is afforded by a visit to an STD clinic, in most public clinics a Pap smear is not part of the routine examination of women. Furthermore, the relative contribution to the homeostatic response by TCR and cytokine signals is not fixed and critically depends on both the degree of lymphopenia and specific characteristics of individual T cell clones.

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Involvement of the infralimbic cortex and CA1 hippocampal area in reconsolidation of a contextual fear memory through CB1 receptors: Effects of CP55,940. In contrast to tsr and km (kanamycin resistance gene), ermE and am were suitably expressed in A. Research is recognised in all applications to United Kingdom and Ireland specialist training programmes, and points are awarded, though many juniors who enter these will have found it difficult to do any research during their careers to date.

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The protocol of this study was developed to investigate the hypotheses whether i) SCI impairs NK cell function throughout the post-acute and sub-acute phases after SCI and ii) the degree of impairment relates to lesion height and severity. Sexual variations in the metabolism of antipyrine in vivo and in vitro

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This will result in high levels of lactic acid production, and this lactic acid must leave the cells for their normal intracellular pH to be maintained. This glycogen is found intracellularly but is not associated with the outer membrane on the mucoid colony variant that predominates after passage in animals--the large colony type. Following a single-step immunoaffinity purification, the protein resolved as a single band of approximately 56,000 MW on sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE).

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These results may furnish some insights concerning ANF receptor binding activity and its putative regulatory role of different cardiac functions. In summary, careful attention to nutrient delivery in the IUGR infant is important to prevent and treat neonatal metabolic derangements and to improve postnatal growth. In a group of 442 patients treated with anti-TNF, three women with RA unexpectedly became pregnant One treated with etanercept chose a therapeutic termination at two and a half months, despite of any ultrasound anomaly, and satisfactory fetal growth. However, male circumcision of HIV-positive men has no effect on HR-HPV infection in their female partners.

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Lactate dehydrogenase and creatine kinase isoenzymes in human vitreous humor. These regulatory pathways converge and contribute to adapt cholesterol uptake and synthesis to the cellular needs. Beta-trace protein, a new marker of GFR, may predict the early prognostic stages of patients with type 2 diabetic nephropathy. The recent realization that dysesthetic vulvodynia and vulval vestibulitis may be regarded as pain syndromes is proving a fruitful concept as regards both theory and management of these troublesome conditions.

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The application of these antibodies to the study of myogenesis is discussed. Analysis of LE-ACS3, a 1-aminocyclopropane-1-carboxylic acid synthase gene expressed during flooding in the roots of tomato plants. The Court also stated that, in cases where a pregnant woman with parental authority petitions to have an abortion, the law mandates that the fetus be represented legally and that the court must consult the Ministry of Minors before it authorizes an abortion.

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Terminology confusion is due to the rarity of this entity and lack of its biology knowledge. To evaluate the association of sustained VT/VF and its timing on the outcomes of patients presenting for primary PCI-an aim not prespecified in the APEX AMI trial.

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A statistical procedure to selectively detect metabolite signals in LC-MS data based on using variable isotope ratios. The suboptimal mass (400 or 1000) of isogeneic PI was transplanted into either the portal vein or under the kidney capsule of diabetic Brown Norway (BN) rats. Monitoring and management of raised intracranial pressure (ICP) in the intensive care unit with an analysis of one year of intracranial pressure monitoring. These results suggest that NTN and its receptor are involved in retinal postnatal development and maintenance and that alterations in their transcription patterns are associated with inherited retinal degeneration.