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Western-blot performed with HL-60 cells confirmed that ERK1/2 and p38 MAPK pathways were stimulated by aldosterone. A review of mechanisms of circumvention and modulation of chemotherapeutic drug resistance. Zinc ions can mediate interactions between hu3S193 Fab in crystals and in solution. In particular, they take tens of milliseconds on current workstations for local deformations and chain closures on molecular chains consisting of six or fewer rotatable dihedral angles. This cross-sectional institutional study included 18 eyes with NAION (at least 6 months since the acute event) and 29 eyes with glaucoma, both having localized visual field (VF) defects confined to one hemifield.

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In psoriatic arthritis anterior chest wall syndrome, insertion tendinopathies, and localized or diffuse bone disease are often observed. The catalytic site of serine proteinases as a specific binding cavity for xenon. Plasma catecholamine levels in the diagnosis and management of pheochromocytoma. Lateral retinacular release as a function of femoral component rotation in total knee arthroplasty.

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The use of optical fibers makes it possible to freely move the sampling volume of the LDV. This could arise from enhanced acyl-CoA:cholesterol acyltransferase (ACAT) activity and/or inhibition of cholesteryl ester hydrolase (CEH) activity. The values of the life tables are shown to be consistent with those of earlier studies.

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We report on a 74-year-old female patient with a venous malformation of the cheek and its successful surgical treatment. Anatomical variants of aortic pseudotruncus (pulmonary atresia with interventricular defect) A high speed centrifuge is described in which the speed is limited only by the strength of the material of which the rotor is made.

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Pathway from the zona incerta to the superior colliculus in the rat. Vascular anatomy and the morphologic and hemodynamic classifications of gastric varices and spontaneous portosystemic shunts relevant to the BRTO procedure. The optimization reduced the fluoroscopy KAP rate from 44 to 16 mGy cm(2)/s using 15 cm of acrylic. We investigated the various genes involved in resistance to fluoroquinolones, aminoglycosides, cephalosporins, and carbapenems in 75 clinical Acinetobacter isolates from a Taiwanese hospital. Pharmacokinetics explain in vivo/in vitro discrepancies of carcinogen-induced gene expression alterations in rat liver and cultivated hepatocytes.

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Virus titers in lungs and brain were substantially lower in infected mice treated with a single dose of CS-8958 than in those treated with the five-day course of oseltamivir. With an average age at diagnosis of 60 years and a 25-year expected duration of survival, the current number of breast cancer survivors in the United States may approach 2.5 million women. Immunopathogenesis and diagnosis of tuberculosis and tuberculosis-associated immune reconstitution inflammatory syndrome during early antiretroviral therapy. The retina presented all the typical layers found in vertebrates, regardless the species. Properties of squeezed number states and squeezed thermal states.

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The liquid-phase microextraction (LPME), based on disposable hollow fiber, has been developed to be a new environmentally benign sample preparation technique which incorporate sampling, extraction and concentration into a single step. Although the optimum level varied depending on each of the examined hydrolytic enzymes, it usually fell in the range around 50 micrograms/kg body weight. Although no vaccine trial in a permissive model of filariasis has provided sterilizing immunity, great strides have been made toward developing vaccines that could block transmission, decrease pathological sequelae, or decrease susceptibility to infection.

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The neurons that comprise the gastric mill CPG consist of one interneuron, five burster neurons and six tonically firing neurons. By tearing at different preparative stages, various cellular structures appeared on SEM: the outer surface of cells, the inner surface of plasmalemma, and the interior of cells. The duration of contraceptive effect is to be determined in an upcoming study.

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Scientists investigating the production of interhalide products (bromine and iodine producing interhalides) in frozen aqueous solutions have found that these reactions result in both rate accelerations and unexpected products. We described two cases emphasizing the clinical and laboratory features of uterine haemangiopericytoma. These experiments suggest that AdOx affects an early event between receptor binding and uncoating, but not reverse transcription.

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ChemEx: information extraction system for chemical data curation. The disease is heterogeneous and is classified as pauciarticular, polyarticular, or systemic-onset disease.

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The reduction of Pref-1 mRNA was most dramatic in differentiating preadipocytes treated with IL-11, occurring despite inhibition of adipogenesis, as judged by cell morphology and adipocyte-specific gene expression (adipsin and glycerol-3-phosphate dehydrogenase). Health problems and illness of female workers in textile industries These results suggest that a) HMGI-C gene may be correlated with the formation of breast tumors and b) the expression of HMGI-C gene may be of pathogenetic and prognostic importance in human breast cancer. Steroid infiltration of tendon sheath: a contraindication to subsequent tendon use for reconstruction? Diabetic nephropathy is one of the most common complications in diabetes mellitus.

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Thus, targeting the stroma and the tumour represents a promising therapeutic strategy. True symmetry or pseudosymmetry: 5-amino-1-(4-methylphenylsulfonyl)-4-pyrazolin-3-one and a comparison with its 1-phenylsulfonyl analogue. Later hominids had very flat trapeziometacarpal joints and large distal phalanges, indicating a capacity for opposition of the thumb to all four fingertips and for tolerance of large stresses. Despite considerable progress during the last decades, mechanical heart valves still have significant disadvantages in performance compared to native valves. Furthermore, ectopic expression of a constitutively active Stat3 antagonized androgen deprivation-induced cell death of LNCaP cells.

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In this pilot study, patients with PCOS showed a reduced salivary relative abundance of Actinobacteria. An investigation established that out of 10 yeast species isolated from the digestive tract of the cockroaches fed sterile food, 6 species (Candida glabrata, Cryptococcus magnus, Debaryomyces hansenii, Metschikowia pulcherrima, Phodo-torula glutinis, Rhodotorula mucilaginosa) were isolated from both the digestive tract and excrements and 4 (Candida oleophila, Candida shehatae, Cryptococcus albidus, Pichia membmnaefciens) were only from the digestive tract. We describe a case of metachronic transformation of ileal and rectal endometriosis into an adenocarcinoma occurring in a 45-year-old female without macroscopic pelvic involvement of her endometriosis.

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The simplified technique is applicable to tomographic systems equipped with a cephalometric head positioner (cephalostat) and a fiberoptic positioning light system. Using this approach, we demonstrate that although there is an apparent lower efficiency of association of the mutant NC1 domains, they can drive the formation of correctly aligned triple helices with the same thermal stability as the wild-type collagen.

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One possibility is that leptin resistance is confined to the metabolic effects of leptin, with preservation of its sympathoexcitatory actions. Shared Decision Making in mental health care using Routine Outcome Monitoring as a source of information: a cluster randomised controlled trial. Effect of Sacral Neuromodulation on Outcome Measures and Urine Chemokines in Interstitial Cystitis/Painful Bladder Syndrome Patients.

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The academic participation and its influence on the professional life according to the perceptions of nurses Our study indicates a proportionally higher area of hyaluronan expression in DCIS with a microinvasive component than in pure DCIS, suggesting a key role of this glycosaminoglycan in the early invasive phase of breast carcinomas. Pulmonary infiltrates are still a frequent cause of hospital admission in the HAART era, and BP is the main etiology.

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Pathogenesis of secondary hemorrhages in compressions of the spinal cord and its roots by ventral neoplasms Oligodeoxynucleotides as antisense inhibitors of gene expression.

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Thus, fibroblasts from keloids and hypertrophic scars overexpressed fibronectin in vivo relative to normal skin and normal scar and retain this characteristic in vitro relative to normal skin. Activin A at a concentration of 50 ng/ml can inhibit the spontaneous activation of human primordial follicles in vitro indicating that this may be a component of the signalling mechanisms that maintain follicular quiescence. Sharks and amphibians have retained the ability to form all three allelic isozymes in individuals which are heterozygous. We investigated patient reported goal achievement, overall satisfaction and objective outcome following the midurethral sling (MUS) procedure for female stress urinary incontinence (SUI).

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It may be appropriate to offer screening to all at risk individuals. Knowledge and practices of physicians regarding health status and health care services for older people in transitional Kosovo. Afterdepolarization mechanism in the in vitro, cesium-loaded, sympathetic preganglionic neuron of the cat. nucleic acids, proteins and peptides during electrophoretic separations in gels.

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Growth retarded fetuses showed a delay in the integration of behavioural patterns and a lower coincidence of behavioural states. Surgical tactics and outcome of treatment in jugular foramen schwannomas.

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A behavioural weight reduction treatment model for use with retarded adults is discussed. Fibrin gel network characteristics and coronary heart disease: relations to plasma fibrinogen concentration, acute phase protein, serum lipoproteins and coronary atherosclerosis. Physical challenge, but not psychological challenge, resulted in an overall increase in heart rate and saliva cortisol. The aim of the study was to compare the cost-effectiveness of group treatment, already known to be more effective, with routine counseling in obese children. The relationship between surface tension and surface area has been measured on each of three common pulmonary surfactants - dipalmitoyl lecithin (DPL), dipalmitoyl phosphatidylethanolamine, and sphyngomyelin-under simultaneously simulated physiological conditions.

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Treatment of closed tibial fractures by Ender nailing and results Eight freshly caught Australasian mass collections ranging in Adh F frequency from 4 to 96 per cent were each divided into eight selection lines. Impure and pure samples of saccharin (2 milligrams per milliliter) did not produce oncogenic transformation of C3H/10T1/2, clone 8, mouse embryo fibroblasts.

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The clinical significance of this combination of obstructive colitis with rectal carcinoma is briefly discussed following the presentation of this case. Gas chromatographic method for the estimation of acetone and its metabolites in biological samples. A method is derived that permits a determination of the upper limit of daily UVR exposure of the in-vivo IOL (or, for that matter, the crystalline lens) based upon knowledge of the ambient outdoor UVR exposure to the head and the threshold for photokeratitis.

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Abnormalities on diffusion tensor imaging (DTI) have been shown to be associated with perinatal white-matter injury and reduced fractional anisotropy (FA) has been reported in patients with sensorineural hearing loss. In this communication, the experience with the use of caudal anaesthesia in the outpatient and ward setting to evaluate painful anal conditions is presented. Fine cytogenetical analysis of the band 10A1-2 and the adjoining regions in the Drosophila melanogaster X chromosome. The raphe region showed cell bodies and processes similar to those previously identified as monoaminergic by other authors. However, transradial cerebral angiography is not utilized to the same extent.

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Subsequently, the uppermost derivative of the basal daughter cell, which is normally destined to become the hypophysis, divided abnormally and failed to generate the quiescent centre of the root meristem and the central root cap. Current strategies in patients with urinary diversion, I: the lower urinary tract

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Measuring gas leakage from bronchopleural fistulas during high-frequency jet ventilation. Atopic dermatitis: immunological mechanisms in relation to phenotype. Risk of Helicobacter pylori infection among long-term residents in developing countries. Production of nitrogen dioxide during nitric oxide therapy using the Servo Ventilator 300 during volume-controlled ventilation.

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Bacteria identified in paranasal sinus pus were compared with those identified in orbital and/or intracranial infections. Paracoccidioides spp., which are temperature-dependent dimorphic fungi, are responsible for the most prevalent human systemic mycosis in Latin America, the paracoccidioidomycosis. Addition reactions of ROPHy/SOPHy oxime ethers: asymmetric synthesis of nitrogen containing compounds. The impairment of verbal memory and learning ability was decreased significantly.

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For games with multiple players and more than two strategies, we show that statements derived for pairwise interactions no longer hold. GeStoDifferent explores the space of GRNs by filtering the NRBN instances inconsistent with a stochastic lineage differentiation tree representing the cell lineages that can be obtained by following the fate of a stem cell descendant. Treatment of relapsed acute lymphoblastic leukemia: approaches used by pediatric oncologists and bone marrow transplant physicians. Biological mode of action of Clostridium difficile toxin A: a novel enterotoxin.

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We have been developing methods which would allow fast transients to be studied on the much smaller quantities of protein available from individual drosophila muscles, single mammalian muscle fibres, human biopsies and non-muscle myosins. Triple therapy with Az in 1990 and 1994 and with MMF in 1998 were the most frequently used immunosuppressive regimens in the Spanish kidney transplant population. The possible role of co-precipitating antibody in some humoral and cellular immune mechanisms is discussed. These findings emphasize the need for more effective treatment of epilepsy and also highlight the importance of a psychosocial approach to management of epilepsy for patients with an early onset of symptoms in order to prevent social limitations in adult life.

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Population redistribution policies of the 4th Plan of National Economic and Social Development (1977-81), aimed at relieving the pressures on Bangkok, are listed. These unexpected differences between fibroblastic and lymphoblastic cells suggest that phenotypic expression of p53 deficiency is cell type specific. Consideration is given to regional differences and to differences between rural and urban areas.

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Endogenous versus exogenous change: change detection, self and agency. Most of the preventable incidents involved human error (82 per cent), with breathing-circuit disconnections, inadvertent changes in gas flow, and drug-syringe errors being frequent problems. Described here is a computer program that provides estimates of theoretical cancer levels in a community following long-term exposure to contaminants found in domestic drinking water. These changes in the free cortisol concentration in cord plasma, rather than constituting a primary event in the onset of labor, may reflect the stress of vaginal delivery on the fetus.

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The Chinese forearm flap is a versatile flap in hand reconstruction. Confirming the role of Ikaros in the induction of T-cell anergy, cells with reduced Ikaros activity show defective inactivation in response to an anergizing stimulus. Run-time interoperability between neuronal network simulators based on the MUSIC framework. Endometrial abnormalities in three sisters from a family with hereditary non-polyposis colorectal cancer syndrome. Our results suggest a complex interplay of various stress response pathways triggered by low radiation doses, with various low dose thresholds for different genes.

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Myasthenia gravis: remission not induced by blocking anti-idiotype antibodies. Uterine sarcomas are rare cancers characterized by clinical and histological polymorphism.

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Phacoemulsification versus trabeculectomy in medically uncontrolled chronic angle-closure glaucoma without cataract. The value of Polish field grown sweet pepper cultivars for freezing and pickling

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There is general agreement that several distinct subpopulation of lymphocytes, including major histocompatibility complex (MHC)-restricted T lymphocytes and non-restricted natural killer, or lymphokine-activated killer (LAK), cells are active in lysing neoplastic cells. In this study rapid detection of ESBL production among clinical isolates of Salmonella was evaluated using double-disk synergy test in a new chromogenic medium. Records included panoramic radiographs and computed tomographic scans.

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Levels were probably not high enough to be a serious threat to bears. In the last 2 decades many efforts have been made to explore at molecular levels the mechanism underlying these defects.