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Primary human keratinocyte cells were immortalized by transfection of HPV-18 and made tumorigenic with nitrosomethylurea treatment. Pediatric Miller Fisher syndrome requiring intubation: a case report. Accurate determination of human serum transferrin isoforms: Exploring metal-specific isotope dilution analysis as a quantitative proteomic tool.

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Effect of L-thyroxine therapy on lipoprotein fractions in overt and subclinical hypothyroidism, with special reference to lipoprotein(a). Unexpectedly, we determined that one of the AT-hook domains is required in a promoter-specific manner. More than a third of the isolates were from lesions related to the gastro-intestinal tract and a quarter from abscesses of various other sites.

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The limited studies on the consequences of the separation process on suicidal behaviour seem to indicate that separated people are at increased risk of suicide. Here we show that mutation or deletion of a putative nuclear export sequence in LTV1 is strongly dominant negative, but the protein does not accumulate in the nucleus, as expected for a mutation affecting export.

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Sephadex LH 20 columns have been investigated for the separation of initial prostaglandin metabolites. Analysis of the interactions between the C-terminal cytoplasmic domains of KCNQ1 and KCNE1 channel subunits. In contrast, those cultured in the medium without bFGF distributed as a cluster and did not participate in host cartilage pattern formation. sTarPicker: a method for efficient prediction of bacterial sRNA targets based on a two-step model for hybridization.

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The following metals and metalloids have been measured by AAS: Fe, Zn, Cu, Cr, Ni, Pb, Cd, Hg, As, Se. Lysis of horse red blood cells mediated by antibody-independent activation of the alternative pathway of chicken complement. Sarcomatous intrahepatic cholangiocarcinoma (ICC) is a rare histological variant of ICC.

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The present study aimed at analyzing the differences in rugae pattern among Kodavas and Tibetan populations of Coorg, India and to examine if there was a difference in the rugae pattern between males and females within each group. Interactions between GRA proteins of dense granules in Toxoplasma gondii and host cell proteins were analyzed by yeast two-hybrid technique. Oxytocin Protects Hippocampal Memory and Plasticity from Uncontrollable Stress. Enlarged coronary sinus, right atrium and right ventricle were documented by UCG.

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Adenovirus DNA polymerase is phosphorylated by a stably associated histone H1 kinase. Effects of metalloporphyrins on hemoglobin formation in mouse Friend virus-transformed erythroleukemia cells. Troxipide (100, 200, 300 mg/kg) and cetraxate (100, 300, 1,000 mg/kg), given orally, dose-dependently protected the gastric mucosa from damage due to ethanol. Together, these approaches established the BR signal transduction cascade, which includes BR perception by the BRI1 receptor kinase at the cell surface, activation of BRI1/BAK1 kinase complex by transphosphorylation, subsequent phosphorylation of the BSK kinases, activation of the BSU1 phosphatase, dephosphorylation and inactivation of the BIN2 kinase, and accumulation of unphosphorylated BZR transcription factors in the nucleus. Perfluorooctanoate (PFOA) has been associated with impaired lactation in mice.

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Medical therapy generally includes a platelet antiaggregant, blood pressure control, and a statin. The parallel decrease in IGF-I and GHR and in their corresponding liver mRNAs suggests that decreased serum IGF-I and liver GHR were likely to result from decreased liver synthesis. The aim of the study was to investigate the need for pressure change in patients with sleep-disordered breathing (SDB) several weeks after therapy initiation.

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Previous studies provide evidence that SAPT may improve clinical outcomes among people with type 1 diabetes. Although patients with metastatic spinal cord compression (MSCC) have a median survival time of 3 to 6 months, few data are available concerning the presence of advance directives and do-not-resuscitate (DNR) orders in this population. Three-dimensional (3D) treatment planning is an integral step in the treatment of various cancers when radiation is prescribed as either the primary or adjunctive modality, especially when the gross tumor volume lies in a difficult to reach area or is proximal to critical bodily structures. To investigate a case of Creutzfeldt-Jakob disease (CJD) possibly acquired from contaminated neurosurgical instruments.

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Direct measurement of middle ear pressure through the eustachian tube. This is supported by early joint registry data, which demonstrate a survival advantage with cementless fixation in one design of UKA. Consistent with these findings, treatment with the AKT inhibitor triciribine sensitized HEATR1-depleted PDAC cells to gemcitabine, suggesting that this therapeutic combination may overcome gemcitabine resistance in patients with low HEATR1 expression.

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Although this practice is appropriate for high-risk patients when skin is contaminated, it is not recommended for noneroded, noninfected skin. Subsequent investigations suggested an anaphylactoid reaction to suxamethonium, but there were features in common with a carcinoid crisis. Botulinum neurotoxins (BoNTs) inhibit neurotransmitter release from peripheral cholinergic synapses. Several factors beyond the confines of treatment settings influence treatment outcome in alcohol dependence syndrome.

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Subsequent catheterization confirmed left anterior descending artery disease. Possible sites of dopaminergic inhibition of gonadotropin release from the pituitary of a teleost fish, tilapia.

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Liver iron concentration was determined non-invasively by magnetic resonance imaging (MRI). The genetic polymorphisms of Mn-SOD (G5774A) and EC-SOD G (-4466)T genes were determined by DNA sequencing and polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). The role of heparin-sensitive and -insensitive pathways in the stimulation of smooth muscle cell migration and proliferation.

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Computer techniques have been developed which enable maximal use of the on-line system while retaining the general flexibility of high-level language coding, as implemented on an unsophisticated 12-bit processor. Future large, well-designed randomized clinical trials using active controls in service members and veterans with co-occurring pain and psychological health conditions are necessary to provide more precise clinical guidance. Sulfinpyrazone and lipoproteins: absence of effects on serum lipids in hyperlipoproteinemias of types II and IV There was a direct relationship between the concentration of industrial effluent and the chloride, ammoniacal nitrogen and carbon dioxide content of water, but no correlation with pH and dissolved oxygen.

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Suppression of dominant-negative inhibitors of TRPV6-specific currents was achieved by deletion of ankyrin (ANK) 3. In this study, we applied a forest landscape model in combination with field studies to evaluate the effects of the three harvest alternatives on mitigating oak decline in a Central Hardwood Forest landscape. Relation between HPV-DNA and expression of p53, bcl-2, p21WAF-1, MIB-1, HER-2/neu and DNA ploidy in early cervical carcinoma: correlation with clinical outcome.

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In both strains, the cholesterol-rich diet increased both the activity and mRNA for 7 alpha-hydroxylase, a compensatory response to maintain cholesterol homeostasis. Stromal-derived factor-1 (SDF-1) is a CXC chemokine that attracts leukocytes and endothelial progenitor cells. These data could be important for understanding the potential dangers of each drug and ultimately preventing adverse health complications associated with acute drug-induced intoxication. (Cucurbitaceae): endemic in southern Tunisia and used in folk medicine to treat many inflammation disorders. The absolute control consisted of quails living in normal Earth conditions, in the laboratory group the quails were exposed to conditions of hypergravitation and hypodynamism in a specially constructed centrifuge, and in the flying group the quails were exposed to space flight in a Soviet orbital station MIR.

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When amoebiasis is suspected, knowledge of the trophozoite and cyst forms may be helpful in distinguishing Acanthamoeba species from Entamoeba histolytica. Enhancement of cellular uptake and antitumor efficiencies of micelles with phosphorylcholine. Phycobilisomes: macromolecular structure and energy flow dynamics.

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Treatment targets in systemic lupus erythematosus: biology and clinical perspective. On the origins of the universal dynamics of endogenous granules in mammalian cells. Complications occur in a considerable proportion of living donors for liver transplantation.

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A retrospective medical record review of asthmatic children attending a community hospital in the South Bronx area of New York City was performed. It suggests that live supervision is a powerful and effective tool--a tool that engenders strong emotional responses. Plasma erythropoietin (Ep) activity was detectable in fetal rats near term and in rats less than 2 old.

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Simulations using finite element analysis and computer modeling were employed to verify and optimize the performance of the proposed instrument before and during its fabrication. Very high levels of expression are required to make the enzymes cost-effective. Discriminative stimulus effects of ethanol in mice lacking the gamma-aminobutyric acid type A receptor delta subunit. Maternal occupational and hobby chemical exposures as risk factors for neural tube defects.

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The development of myeloid leukemias and myelodysplastic syndrome (MDS) is common in children with trisomy 8 mosaicism. We demonstrated that bone marrow MSCs were capable of generating bone structures and bone-associated marrow elements on the surfaces of the orofacial bone. Si-H bond activation of alkynylsilanes by group 4 metallocene complexes.

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Properties of long human telomeric DNAs under cell-mimicking conditions. Sperm agglutination, immunofluorescence localization, and flow cytometric analysis of surface expression of A36 antigens. Despite VFA accumulation adaption of the microorganisms to the changing conditions and high buffer capacity resulted in steady methane production. Evidence-based clinical data are required for safe return to play after concussion in sport.

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Antigen presentation by B lymphocytes: how receptor signaling directs membrane trafficking. The WHO officially declared the outbreak to be a pandemic on June 11, 2009. Recently, emerging evidence has demonstrated that microRNAs (miRNAs) are critically involved in drug resistance. A 20-year history of smoking mitigated the prognosis in this particular case. However, partial vitreous detachment was shown, retrospectively, to stimulate a rapid exacerbation of the proliferative process as compared with eyes having no vitreous detachment or complete vitreous detachment.

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Whether a surgical procedure meets the standard of care is determined by expert witnesses evaluating the evidence. Although the P2 promoter was always weaker than the P1 promoter during neuronal differentiation, their activities increased by 7- and 5-fold, respectively, and correlated with MR expression. There was no injury of blood vessel or spinal cord during the surgery.

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There was no detectable signal of positive selection at species-specific GR binding sites, but clear evidence of purifying selection at the small number of conserved sites. Our results show that surgery should be performed sooner rather than later. The gut, particularly the colon, is the host of approximately 1000 bacterial species, the so-called gut microbiota.

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In total, 11 interviews were held with professionals at four different institutes. To evaluate a new range of chromogenic substrates for the detection of beta-galactosidase activity in coliforms and to compare their performance in agar media and broths.

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Probabilities of false positives and false negatives are considered and recommendations are made for appropriate transformation of data, experimental design, and test conditions. Pushed by opponents of abortion, legislative bills are pending this year in at least nine US states which would require that women seeking abortions receive information about an increased risk of breast cancer. During the light phase, the amount of NFKB increased continuously, and a sharp drop occurred when lights were turned off. These findings indicate that nasal oxygen has distinct effects on ventilation and heart rate in chronic heart failure.

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The purpose of this study was to evaluate the accuracy of the recently developed echocardiographic on-line endocardial border detection system using ultrafast computed tomography, an independent and proved tomographic imaging modality. Bone marrow suppression and hepatic dysfunction are serious adverse effects that should be kept in mind when using long-term TZP. Acetic acid and hydrogen metabolism during coculture of an acetic acid producing bacterium with methanogenic bacteria.

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