Alizar is a potassium sparing diuretic like eplerenone that competitively inhibits mineralocorticoid receptors in the distal convoluted tubule to promote sodium and water excretion and potassium retention. Alizar was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered. It is indicated to treat a number of conditions including heart failure, deem, hyperaldosteronism, adrenal hyperplasia, hypertension, and nephrotic syndrome. Off label uses of Alizar involving its antiandrogenic activity include hirsutism, female pattern hair loss, and adult acne vulgaris. Alizar is also frequently used in medical gender transition. Alizar was developed in 1957, marketed in 1959, and approved by the FDA on January 21, 1960.
Other names for this medication:
Spironolactone,
Aldactone,
Aldactazide,
Aldactazine,
Aldazida,
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Aldozone,
Alexan,
Alizar,
Carpiaton,
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Spiron,
Spirono,
Spironolacton,
Spironolactona,
Spironolakton,
Spironolattone,
Spirotone,
Verospiron,
Xenalon,
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A pseudoephedrine hydrochloride alcohol interaction with levofloxacin 51-year-old man presented with a nonpulsatile anterior neck mass which suggested a thyroglossal duct cyst. Preterm infants born between January 2011 and December 2015 with late-onset sepsis were enrolled in our retrospective study and were matched with healthy controls (sex, birth weight and gestational age).
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