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The aim has been to identify the role of interleukin-6 (IL-6) signaling and its predictive power in the treatment response of pharyngeal cancer. The generic function and broad tissue distribution of the uncoupling protein family means that they are increasingly implicated in a range of pathophysiological processes including obesity, insulin resistance and diabetes mellitus, neurodegeneration, cardiovascular disease, immunity and cancer.

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Poorly differentiated tumor regions appeared to express NAT1 at lower levels than did well-differentiated areas. One of these was fursultiamine, a Food and Drug Administration (FDA)-approved thiamine derivative. Semi-adherent K562 cells bearing the Fc-gamma receptor (Fc gammaR) were cultured on poly-L-lysine-coated plates. In this study we immunohistochemically determined, using human umbilical cord tissue, whether or not NMC-VIII/10 has an inhibitory effect on FVIII binding to endogenous vWF in endothelial cells.

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After 8 days, the dog regained voluntary motor function in all four limbs. Detection of the binder may be clinically valuable as a possible marker in the diagnosis of gastric cancer. To test the clinical and sonographic predictors of testicular torsion (TT) with the aim of reducing negative exploration rates. This makes it difficult to develop perioperative records with pertinent data elements without creating redundancy, errors, and inconsistencies.

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Thus, combination of a higher dose of nicotine (0.125 mg/kg) with apomorphine, reduced apomorphine-induced grooming. Effect of vitamin A deficiency on RNA synthesis in isolated rat liver nuclei. Iron administration in pregnancy--general prevention or indicated therapy

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The stimuli were presented monaurally at 10-, 30-, and 50-dB HL, with regard to adult behavioral thresholds. The substitution of His-296 with Tyr by means of site-directed mutagenesis induced a drastic decrease in the reaction rate, while a His-205 to Tyr substitution induced no large change in the catalytic properties.

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By the results evidence accrued that in advanced stages of liver cirrhosis and a marked porto-caval collateral circulation polymerization of fibrinogen was insufficiently, especially, the formation of alpha-chains was altered, whereas the formation of gamma-dimers, the separation of fibrinopeptides from fibrinogen, and the aggregation of fibrinmonomers were normal. MB-mediated photokilling was inhibited more significantly than that of TB. High-throughput screening projects based on RNAi have been initiated to search for genes involved in basic biological processes and in complex pathological conditions such as cancer, autoimmunity and degenerative disorders. These 8 patients with a male to female ratio of 1:1 were initially misdiagnosed as a variety of rheumatic diseases such as erythema nodosa, nodular panniculitis, systemic vasculitis, etc.

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However, a hierarchical linear regression revealed a significant amount of unique contributions to the variance in CF based on each of the measured concepts. On the day that I-FABP levels increased, findings of biopsy specimens were consistent with early rejection. Resting ECG in athletic and non-athletic adolescent boys: correlations with heart volume and cardiorespiratory fitness. Acetylcholinesterase in the substantia nigra and caudate-putamen of the rat: properties and localization in dopaminergic neurons. Airway remodeling changes are a key pathological feature of asthma.

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In addition, one patient had a large pancreatic cyst with internal echoes. This entity should be considered in the differential diagnosis of stridor. Compared to the control and the antisense transgenic tobacco plants, the fast development and blossom of the sense transgenic plants happened to promote senescence.

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In the present study, we examined the effects of ondansetron, a selective 5-HT(3) antagonist, on CCK-induced suppression of solid chow intake. Quasilinear theory of the ordinary-mode electron-cyclotron resonance in plasmas.

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Hepatocellular dysfunction after severe hypotension in the absence of blood loss is associated with the increased IL-6 and PGE2. 3D Navigation on Impossible Figures via Dynamically Reconfigurable Maze. Clinical haemovigilance data, so far, indicate that cell-free MB plasma is effective in all therapeutic setting requiring FFP, besides inconsistent thrombotic thrombocytopenia purpura data, without serious side-effects or toxicity. Enantioseparations by capillary electrophoresis using cyclodextrins as chiral selectors. The characteristics of apoptotic cells were evaluated by morphological observation and TUNEL staining.

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Observation method: An infrared thermal image of the face was taken before and after suspended moxibustion using a CK350 medical infrared thermal imaging instrument. Previous work conducted in our laboratories established the notion that TPGS 1000 (d-alpha-tocopheryl polyethylene glycol 1000 succinate), a nonionic surfactant, modulates P-glycoprotein (P-gp) efflux transport via P-gp ATPase inhibition. While the total cell number of lower organisms is often known, it has not yet been defined in higher organisms. Myasthenia gravis, an autoimmune disorder of the neuromuscular junction, is usually recognized because of ocular complaints or generalized weakness. In the presence and absence of smg GDS, rho GDI reduced the velocities of these nucleotide exchange reactions of rhoA p21 and rac1 p21 to similar extents.

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The bile acid sequestrants accounted for a small fraction of the overall use (0.23 DDD/inhab/day in 1991), in spite of its increasing consumption. Binding of Haemophilus influenzae to purified mucins from the human respiratory tract.

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The present trend towards a more aggressive operative policy in acute cholecystitis has led to a search for more accurate methods of diagnosis. In addition, signed syntactic violations elicited an early frontal negativity and a later posterior positivity. Electrocautery-induced asystole in a scoliosis patient with a pacemaker. To construct human osteosarcoma 9901 cell cDNA expression library for screening osteosarcoma-specific antigens.

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Outpatient treatment with (131)I-anti-B1 antibody: radiation exposure to family members. These structures are considered by some to represent the intraparotid facial nerve. The relevance of these results on the interphase properties of lipid membranes is discussed. Conversion of overlap data to probe-like data elements would facilitate comparison and uniform integration of overlap data and probe data using software developed for analysis of STS data.

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The apo B/apo A-I ratio and the apo B/TC ratio were high in the early stages of illness. Efficiency optimization in an electron cyclotron autoresonance maser amplifier through magnetic field tapering. This study examines the host-bone response to hydroxyapatite-coated titanium and porous-coated cobalt-chrome stems of identical geometry in three paired bilateral cases at 5 to 7 years.

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Cross-sectional study comparing isometric lumbar extensor strength (ILES) in individuals who smoke and nonsmokers with and without low back pain (LBP). Mechanical ventilation (MV) is used clinically to maintain gas exchange in patients that require assistance in maintaining adequate alveolar ventilation. Catalytic asymmetric conjugate addition of isocyanoacetate to (Z)-3-substituted-2-(4-pyridyl)-acrylonitrile, a reactive class of Michael acceptor. This article reviews current options for the therapeutic management of HDL cholesterol, including discussion of novel agents aimed at reducing cardiovascular disease risk in patients with low levels of HDL cholesterol. Aspergillus penicilloides and Eurotium halophilicum in association with house-dust mites.

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The mechanisms underlying cisplatin resistance are not fully understood. These findings indicate that electrocorticographic mapping of auditory descriptive naming may reduce the risk of permanent post-operative language deficits following dominant temporal or frontal resection. The origin of sex is one of the least understood aspects of the evolution of sex. Bilateral hemichorea-hemiballism caused by metastatic lung cancer. Identification and characterization of outer membrane proteins of Pasteurella multocida serotype D by using monoclonal antibodies.

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The following data were recorded: sex, age, race, medical history, etiology, addictions, degree of bone atrophy, type and size of zygomatic implants, number of implants placed, type of prosthesis, survival rate, and success of implants and complications. The distinct mechanism of budding-yeast Dicers establishes a paradigm for natural molecular rulers and imparts substrate preferences with ramifications for biological function.

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Patients who consult with tiredness: frequency of consultation, perceived causes of tiredness and its association with psychological distress. In this study, we transfected human Fas cDNA into a mouse beta-cell line (betaTC1) and established a beta-cell clone expressing human Fas.

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Painful ophthalmoplegia as an initial presentation of sarcoidosis. Some amino acid changes were also detected in specific branches of phylogeny suggesting that relaxed constraints might also have contributed to functional divergence among sub-families. Recognition and naming of famous buildings: Italian normative data.

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Social interaction and support related to mood and locus of control in cervical and endometrial cancer patients and their spouses. Therefore, although the administration of exogenous FGF to the developing chick embryo in vivo clearly has some biological activity in the CNS, it was nonetheless ineffective in promoting neuronal survival or differentiation. To achieve the goals of the current study, we employed the Edinburgh Postpartum Depression Scale (EPDS). It was found that if the above sequence of steps resulting in the formation of streptavidin-biotinylated transferrin/biotinylated polylysine was followed without isolation of intermediate conjugates by Sephadex G-200 chromatography, pRSVL DNA transfer was still very efficient. Ribosomes are molecular machines that synthesize proteins in the cell.

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Instead, decreased phagocytic ability observed for leukocytes isolated from diabetic mice might account for the impaired bacterial clearance. In contrast, kinase inhibitors are being used increasingly within palliative concepts. Lower frequency of K329E carriers (1/202)) suggests that the incidence of MCAD deficiency will be probably lower in our population than we expected. In this study we further specify the forebrain there is no other known co-localization with 5-HT. Effect of qihuang decoction on epithelial cell apoptosis of ischemia/reperfusion injured intestinal mucosa in rat

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Depletion in IVM rate with administration of CP is due its adverse effects on oocyte quality. To maintain GABA-activated currents, 2 mM Mg adenosine triphosphate (ATP) was added to the intracellular solution. Fourteen pediatric patients with burn sequelae neuropathic pain. Chromatographic preparation of a therapeutic highly purified von Willebrand factor concentrate from human cryoprecipitate.

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Chromosomal abnormalities near the SOX9 gene disrupt the regulation of this gene and prevent the SOX9 protein from properly controlling the development of facial structures, which leads to isolated PRS. An intronless homolog of human proto-oncogene hPTTG is expressed in pituitary tumors: evidence for hPTTG family.

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Influence of plasma treatment on laser-induced damage characters of HfO2 thin films at 355 nm. These proteins not only are indispensable for progenitor cell specification but also are critical for terminal differentiation of multiple cell types in a wide variety of lineages. Recent findings in Drosophila provide a first picture of the molecular mechanism, which appears to be conserved between plants and animals. Compared with control group, different concentration of PCA could increase the number of survival neurons with neurites and the average length of neurites.

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For the control of chronic cancer pain, Durogesic(R) patches (Janssen Co., USA) are now widely used. To quantify the difference in risk of incident myocardial infarction (MI) between men and women. To overcome this limitation, recA and rpoB sequence analysis was evaluated as an alternative for distinguishing Geobacillus species. The D1 receptor mRNA gave a faint signal from gestational day 11 (G11) on, while the D1b receptor was not detectable before G12.

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Here, we describe N-CLAP (N-terminalomics by chemical labeling of the alpha-amine of proteins), a general approach for profiling protein N-termini and identifying protein cleavage sites during cellular signaling. This study reports the 16-year experience of a specialist unit with these tumours, and compares our results with that of recently published series.

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Advances in molecular detection over the past decade, including rapid chromogenic agar and real-time polymerase chain reaction, have improved diagnostic capabilities. The demographic transition in twentieth-century India is analyzed using census data. Compared with patients without a deficiency state, the clinical features of cerebral vein thrombosis were similar except for an earlier onset and a positive medical history of venous thromboembolic events in a considerable number of patients. The patient with the anterior cranial base tumor had a history of hemorrhage into the frontal lobe and partial resection. Isolated febrile intra-alveolar hemorrhage detected in leptospirosis

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Screening for abdominal aortic aneurysm with electronic clinical reminders. Multiple cell-associated proteinases with molecular masses corresponding to 33, 55, 60 kDa (cysteine proteinases) and 77, 80, 90, and 108 kDa (metalloproteinases) were detected using these methods. Relationship of 24-hour blood pressure mean and variability to severity of target-organ damage in hypertension. Likewise the injection of viscid pneumonic exudate, with the animal tilted at an angle most favorable for entrance into the lobe bronchi, did not result in pulmonary involvement.

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Since few network parameters for ethylene signaling are known in detail, we used an evolutionary algorithm to explore sets of parameters that produce behaviors similar to experimental growth response kinetics of both wildtype and mutant seedlings. Amphibians were exposed at different life stages and via different routes to the technical mixtures Clophen A50 and Aroclor 1254 or to a non-ortho PCB congener (PCB 126).

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The laminar analysis of the positive component of the response suggests that it originates relatively superficially in cortex and migrates down toward the deeper layers. Functional and basal cerebral metabolic rate for oxygen (CMRO2) and its relevance to the pathogenesis and therapy of brain injury.

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When compared to sildenafil, sulfoaildenafil contains a sulfur atom substitution for the oxygen atom in the pyrazolopyrimidine portion of the molecule, and a 3,5-dimethyl substitution on the piperazine ring, rather than the 4-methyl moiety. Consent forms appear to be at highest risk for IRB stipulations. Effect of genetic background on the capacity for islet cell replication in mice. The gene 2 product converts the auxin precursor indole-3-acetamide and its analogue 1-naphthalene acetamide into the active auxins indole-3-acetic acid and 1-naphthalene acetic acid.

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In contrast to central nervous system neurons, neurons expressing the type 2 NF1 isoform were identified in the developing dorsal root ganglia and spinal cord by in situ hybridization using a type 2-specific oligonucleotide probe. Arthroscopic repair versus open surgery for shoulder instability. Pneumatosis cystoides intestinalis in AIDS-associated cryptosporidiosis.

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The aim of this study was to present a morphometric reference database for cervical vertebrae of the Indian population and enable comparisons with other populations. Improvement of green tea polyphenol with milk on skin with respect to antioxidation in healthy adults: a double-blind placebo-controlled randomized crossover clinical trial.

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A 83-year-old man was admitted because of fever and painful swelling of the right scrotal contents on January 23, 1989. The media were then mixed with deuterium-labeled amino acids, dried and derivatized.

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Improvements in image analysis and acquisition speed make it important for decision-making in the diagnosis and treatment of this disease. When the polar body nucleus is transformed into a haploid pronucleus, treatment with okadaic acid was used to induce premature chromosome condensation.

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In this review we evaluate the vast amount of in vitro data dealing with antigen presentation, cell-cell interactions, T and B cell activation, and the immunoregulatory role of cytokines, as suggested to be involved in immune responses. Malignant peripheral nerve sheath tumors (MPNSTs) develop in patients with underlying NF1, and usually arise as a result of malignant transformation of a pre-existing plexiform neurofibroma. CSF pulse energy may be the most significant factor in CSF leakage and meningitis, but a bone baffle can block such CSF pulse energy.

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Therefore, its presentation on surfaces of different fungal species was investigated by using antibodies raised against recombinant enolases from A. Previous studies report successful application of laparoscopic pancreatic enucleation (LPE). We analyzed patients treated at our hospital radiation center through February 1981 in an attempt to evaluate the contribution of supradiaphragmatic radiation therapy in this disease. Radiotherapy should be reserved for those few cases where operation is inadvisable. These changes may be due to a decrease in pollutant load, the discharge of ferric chlorates used in the treatment process.

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It is generally accepted that bacterial antigens are processed by the proteasome, a proteolytic cytoplasmic multiprotein complex. Conversely, a social encounter produced an increase in large PSD-95 punctae in the mPFC independently of trial number, but only in ISO rats exposed to an aggressive stimulus rat. Controlled trials investigating alternative protocols in relation to sensitivity, survival, cost and quality of life are important, especially for patients for whom potentially curative treatment is available. Velocity-dependent fluctuations: Breaking the randomness of Brownian motion. Factor and latent class analysis of DSM-IVADHD symptoms in a school sample of Brazilian adolescents.

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A case of late stage cutaneous leishmaniasis with focal caseous necrosis is reported. In the late luteal phase, P supplementation was correlated with a significant decrease in uterine pulsatility index as compared with both spontaneous cycles and FSH-treated cycles without luteal support. Our data suggest that a cognitive bias negatively influences the unimpaired automatic reactions to emotional expressions in depressed patients, and this bias may result in the characteristic social withdrawal. Obesity regulates bioavailable testosterone levels in women with or without polycystic ovary syndrome.