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Immunohistochemical analysis of proliferating cell nuclear antigen demonstrated a very high proportion of proliferating cells in the periphery of desmin (-/-) whole muscle grafts at day 5 compared to the controls, where mitosis in this area was negligible. Censored regression quantile (CRQ) methods provide a powerful and flexible approach to the analysis of censored survival data when standard linear models are felt to be appropriate.

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The concomitant shifts in enzyme expression and metabolite utilization profiles shed light on the regulatory links between cell metabolism, media metabolites, and cell growth. Studies of unfertilized parthenogenetic eggs may therefore teach us much about the process of centrosome assembly in the absence of preexisting centrioles. Accurate and robust estimates of camera position and orientation in a bronchoscope are required for navigation. Surgical rehabilitation in patients aged 70 years and older with temporary intestinal stoma

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Materials used for obtaining drug-collagen hybrids were collagen type I (Coll) as matrix and fludarabine (F) and epirubicin (E) as hydrophilic active substances. Polymorphic arrhythmias are due to changes in wave pictures in the regions of retarded excitation propagation.

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Evaluation of cambendazole paste against nematodes in horses in a field trial. NO-mediated hypoxic cell radiosensitisation by NO donor drugs may offer a new approach for clinical consideration, particularly if such agents can be selectively delivered to hypoxic cells. The aim of this study was to describe an interdisciplinary approach for endodontic therapy of behavior-challenging children and to report the efficacy of sedation techniques for these procedures. The aim of this study was to investigate the expression and release of the IL-1 type II decoy receptor (R) in mononuclear phagocytes, which play a central role in immune and chronic inflammatory reactions.

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Homozygous RpII215ts adult females shifted to 29 degrees C lay structurally normal eggs for 24 hr, after which increasing numbers of eggs are abnormal. Chemical characterisation of polysaccharides from Lilium davidii.

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Structural and functional analysis of the globular head domain of p115 provides insight into membrane tethering. Differentiation was accompanied by an increase in mitochondrial content and respiratory chain activity. Significant protection against acetylcholine and histamine aerosol-induced bronchospasm in B.

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As an environmental protection point of view, the potential toxicity of chitosan on aquatic animal health, alone or associated with copper must be investigated. Here, we demonstrate the stable inversion in the reporter lines, both in somatic cells and in the germ line by Cre or Flp, and the subsequent reinversion using the other recombinase. Second, Literature Aided Statistical Significance Threshold (LASST) was developed to determine the appropriate expression p-value threshold for a given experiment.

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MR imaging is now frequently used for morphologic and functional evaluation after TOF repair. The transition to a market-orientated economy in 1990 increased the risk of becoming work disabled. Evolving through primates to humans, they were influenced by the retraction of the maxillo-facial cranium and the enlargement of the cerebral cranium and thus reached the state unique to humans.

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Of 11 cell lines examined, 5 cell lines had missense point mutations, and each overexpressed p53 protein on western blot analysis. Furthermore the endothelins should not be considered as a hormone but as a paracrine substance.

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This research contributes to a better understanding of the technical limitations in generating germline-competent embryonic stem (ES)/iPS cells and provides valuable clues for overcoming the difficulties of acquiring ground-state iPS/ES cells in other species, including humans. Commercially prepared cadaveric dura mater can be successfully used as a tectonic graft for the treatment of scleral thinning.

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No association of pre-microRNA-146a rs2910164 polymorphism and risk of hepatocellular carcinoma development in Turkish population: a case-control study. Major Depressive Disorder (MDD) is often comorbid with personality disorders which are known to change its clinical aspects and worsen its outcome. The patient had consistently low platelet counts but no clinical signs of a defect haemostasis. However, the functional alterations appeared related to an early tendency to relapse, as both patients developed an acute phase after 5 and 9 months from testing, respectively.

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The program was developed within the context of a research project that investigated the effect on outcome of client-focused approaches to community case management for clients with schizophrenia and bipolar disorder. Syndromes Predisposing to Cancer in Children--the Experience of Pediatric Oncology Departmentof University Hospital Brno PTB smear-negative adult suspects were included in a prospective diagnostic study (2009-2011).

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Cancer deaths that occurred in this population between 1971 and 1988 were compared with death rates published by the Bombay City Cancer Registry. The renal tubular toxicity was evaluated by urinary beta 2 microglobulin (beta 2-MG).

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Experimental UDMA brackets reinforced with silicon dioxide fillers showed an obvious trend for improved mechanical properties compared with unfilled UDMA brackets. These findings support a vital role of HO-1 and its reaction byproduct, CO, in vascular repair through enhancing EPC mobilization.

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Gilbert disease was diagnosed in a 15-year-old boy on the basis of the clinical pattern and the changing drug-metabolizing capacity of the liver-enzyme apparatus, which was drug-induced. There was a direct relationship between conduction velocity and space constant and maximum rate of depolarization.

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Grade I specialization in general medicine prepared in the form of definite expected educational results The number of adherent platelets in sinusoid was observed up to 120 minutes after I/R by IVM. Prediction of paroxysmal tachycardia in patients with Wolff-Parkinson-White syndrome based on electrophysiological study of the heart Additional mutants retained the ability to inhibit WT p53-mediated transactivation in these cell lines.

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All brackets had 0.022-in slots, and the wires were 0.019 x 0.025 in. We hypothesised that an auto bi-level device with pressure relief during exhalation (auto bi-level) would treat OSA as well as CPAP and that transitioning non-compliant CPAP patients without modifiable causes of poor compliance to this device would improve compliance and clinical outcomes.

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Many drugs, especially antibiotics, can produce this untoward effect. Transient oxygen uptake during myocardial reactive hyperemia in the dog. Postoperative PSA-value reduction was significantly higher after treatment with the 180-W laser. We reviewed physician practices regarding PCT test and antibiotic therapy prescription to all patients hospitalized for COPD exacerbation.

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Hereditary canine spinal muscular atrophy is an inherited motor neuron disease that occurs in Brittany Spaniels and has remarkable similarities with human spinal muscular atrophy. Part 6: phytochemical investigation of Euphorbia geniculata Jacq. Transfer of the alkyl group from the substrate to the porphyrin. These results corresponded to literature data, where the patients with non-brain localization of tumors are considered.

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The fourth patient quite obviously did better while taking ibuprofen than she did without medication, and her visual acuity remained about the same as during steroid therapy. This article describes the evolution, current status, and future prospects of the Ontario Telemedicine Network (OTN). Instead higher age cohorts were crowded out, especially the higher age cohorts of males.

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Highly dispersed palladium nanoparticles grafted onto nanocrystalline starch for the oxidation of alcohols using molecular oxygen as an oxidant. Although present three-dimensional CT is not without limitations, the authors believe that the technique is valuable and that, in their experience, it has facilitated preoperative planning.

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Three phases or generations are distinguished, each with distinctive features, advantages, and disadvantages. Predicting heart failure decompensation using cardiac implantable electronic devices: a review of practices and challenges.

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The disorganization of the native tertiary structure by SDS was expressed in a decrease of the circular dichroism bands related to the tyrosine and tryptophan chromophores and in appearance of the vibronic fine structure in the phenylalanine band zone. Moreover, clear differences in the TPO/Ln complexes between classical and ionic media are highlighted. We assessed cardiac involvement in patients with SSc using echocardiography and investigated the association of N-terminal pro-brain natriuretic peptide (NT-proBNP) and asymmetric dimethylarginine (ADMA) with echocardiographic measures of myocardial function in sera of patients with SSc who had no symptoms of heart failure. Disturbance of respiratory muscle function in patients with mitral valve disease.

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Based on the options proposed for reducing the number of FMGs, the conclusion is reached that the primary concern at present is an oversupply of U.S. We retrospectively analysed 62 consecutive paediatric patients in whom FD-CT was used during catheterisation of congenital heart disease.

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All the right moves: how data helps top performers take action--and get results. How four once common diseases were eliminated from the American South.

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Pharmacological properties of R-755, a novel acyl-CoA:cholesterol acyltransferase inhibitor, in cholesterol-fed rats, hamsters and rabbits. Analysis of genetic diversity and molecular evolution of human group B rotaviruses based on whole genome segments. Confounding by time since hire in internal comparisons of cumulative exposure in occupational cohort studies.

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Six symptoms (day cough, night cough, irritability or crankiness, headaches, nasal airway obstruction, and purulent rhinorrhea) were used to assess the outcome of their treatment. Cyclospora cayetanensis - the rare causal agent of diarrhoeal diseases Molecular cloning, sequencing of the gene and overexpression of the enzyme.

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We identified a putative binding site for PI3K at tyrosine 798 in the TLR5 TIR domain, at a site analogous to the PI3K recruitment domain in the interleukin-1 receptor. Identifying gastroesophageal reflux disease as the cause of respiratory and laryngeal complaints is difficult and depends largely on the measurements of increased acid exposure in the upper esophagus or ideally the pharynx. Short communication: relationship between herd intramammary infection incidence and elimination rate during the dry period. Experimental protocols that allow confident assignment of signaling proteins to specific subdomains of the plasma membrane are essential for a full understanding of the complexities of signal transduction. Cell-mediated cytotoxicity in Theileria annulata infection of cattle with evidence for BoLA restriction.

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A moderate activity of lysosomal enzymes, an increased activity of enzymes of electron transport, anaerobic glycolysis, pentose phosphate shunt and decreased activity of those of aerobic energy metabolism were found. We asked subjects to monitor simultaneously vision and audition either at one location (focused attention) or in the two opposite hemifields (divided attention) or to monitor one single modality at one or two locations. Patients underwent an interview, clinical examination, and 3-/4-dimensional pelvic floor ultrasound.

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The role of family caregivers in supporting people with dementia in the community is beyond question. These data show for the first time that FRH promotes lung injury in part by increasing lung epithelial apoptosis.

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Our results have important consequences for understanding the epidemiological and evolutionary dynamics of the influenza virus. Incorporating acellular dermal matrix into these repairs may protect the bone graft during mucosal healing by providing an additional layer of soft tissue coverage. Fast-spiking neurons could fire extremely narrow action potentials at a very high frequency. Effects of 4-dimethylaminophenol in rat kidneys, isolated rat kidney tubules and hepatocytes.

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FK 506 prevents islet xenograft rejection: a study in the pig-to-rat model. Both mouse and human novel Ly9 genes mapped close to the CD229gene in a region where other members of the CD150 family have also been mapped, and analysis of their genomic sequences showed that they have an identical intron/exon organization.

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The studies on biofilm formation of Pasteurella multocida have become imperative since it is a respiratory pathogen and its biofilm mode could possibly be one of its virulence factors for survival inside a host. A simple purification scheme making use of high-performance liquid chromatography has been devised to purify gp150 to near homogeneity. The underlying mechanisms could be associated with the regulation of the cellular senescence-signaling pathway. For immunological studies, therefore, the availability of purified preparations of alpha B-crystallin and its various differentially phosphorylated forms would be especially useful. Although the four ETC complexes and ATP synthase are considered exquisite mitochondrial proteins, they are found ectopically expressed in several membranous structures.

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AV and MR Rasashastra preparations could provide alternatives to synthetic antibiotics against human bacterial infections. Evolutionary dynamics of continuous strategy games on graphs and social networks under weak selection. The simulated results showed that low temperature have a negative effect on the ammonia removal. Evidence for a positive correlation between aging in vitro, as reflected by mean nuclear areas at the tenth doubling from the end of in vitro doubling activity, and donor age is presented.

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Ab initio calculation of 4fN6s2 hyperfine structure in neutral rare-earth atoms. It is shown that if saturation is approached, the response time of the molecular system is strictly related to the pumping time, which is given by the reciprocal of the product of the laser spectral density and the Einstein coefficient of stimulated absorption.

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The quality of the results is surprisingly good, and far exceeds what one might expect, even when the pitch of the helix is large. NF-kappaB in breast cancer cells promotes osteolytic bone metastasis by inducing osteoclastogenesis via GM-CSF.

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With decreased production, the effect of plasma iron on plasma iron turnover was reduced, whereas with increased erythropoiesis there was an additional increment in plasma iron turnover for any increase in plasma iron. The study aimed to establish relationships between QoL scores obtained through the QOLIE-10 inventory and clinical variables in patients older than 18 years diagnosed with epilepsy.