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The results may impact further treatment strategies, such as drug targeting. Diagnostic usefulness of the Carlsson-Dent questionnaire in gastroesophageal reflux disease (GERD) Tetrahydroaminoacridine and D-cycloserine fail to alleviate the water maze spatial navigation defect induced by hippocampal inactivation.

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Reactive oxygen species formed as a response to various abiotic and biotic stresses cause an oxidative damage of cellular component such are lipids, proteins and nucleic acids. The anterior atlantoaxial transarticular locking plate system not only provided stronger fixation, but also decreased screw-bearing stress and screw-bone interface stress compared to simple anterior atlantoaxial transarticular screw fixation. In the adult, the accessory duct and the accompanying pancreatic tissue and glands appeared functional. Chromogranin A, the major catecholamine storage vesicle soluble protein.

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Human plasma aldosterone can be rapidly, directly, and reliably measured by radioimmunoassay with use of a commercially available anti-aldosterone antibody. Product development activity in the past five to ten years has reconstituted a version of an old debate on the safety assessment of biological products, namely whether the use of some types of continuous cell lines (CCLs) is appropriate in the preparation of some types of biological products. A preliminary study using the distribution of the epicardial coronary artery to demarcate experimental myocardial ischemia in dogs

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It bound specifically to calmodulin in the presence of calcium, and strongly inhibited the stimulatory activity of calmodulin on phosphodiesterase. We conclude that the effect of 4beta-phorbol esters is mediated by protein kinase C (PKC).

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Arterial compliance and distensibility are modulated by body composition in both men and women but by insulin sensitivity only in women. The annual effective dose from 137Cs of Chernobyl origin was three orders of magnitude lower as it varied from 70.4 to 410.4 nSv/y (average 199.3 nSv/y). Single-center, double-blinded, placebo-controlled, randomized clinical trial. We performed a pooled published data analysis to identify the factors influencing RR in these 29 studies. Based on the quantity of chlorophyll present in a protoplast suspension, the optimal amount of template is calculated and a fragment of the transgene is amplified.

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Disruption of gap junctional communication (GJC) by various compounds, including growth factors and tumor promoters, is believed to be modulated by the phosphorylation of a gap junctional protein, connexin43 (Cx43). These test methods of neuro-behavioral observations we proposed were able to detect the biological effects of a drug simply and promptly, and contributed sufficient data to support an administrative measure aimed at anticipating and improving the prevention of health damage in humans by non-regulated drugs from a scientific perspective.

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Structure of a novel Bence-Jones protein (Rhe) fragment at 1.6 A resolution. Long-term outcome of extralevator abdominoperineal excision (ELAPE) for low rectal cancer. Compounds of this type are oxidized to semiquinonedi-imines or quinonedi-imines by mitochondria in vitro, establishing alternative pathways for electron transport in the respiratory chain with concomitant decreases in respiratory control and ADP:O ratios. Metabolism of valproic acid by hepatic microsomal cytochrome P-450.

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By inserting random loops of four to seven residues into a dimeric chorismate mutase and selecting for functional variants by genetic complementation, we have obtained and characterized both monomeric and hexameric enzymes that retain considerable catalytic activity. The case of a 48-year-old Japanese man with idiopathic bronchostenosis in the right lower lobe is reported. Predicting arboviral disease emergence using Bayesian networks: a case study of dengue virus in Western Australia. Heart rate and mean arterial pressures were recorded before introduction of the endoscope and thereafter at various stages of the operation.

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The inhibition of proliferation and induction of apoptosis was tested in human lung carcinoma cell line A549 by directly adding survivin-T34A to the cell culture medium. These data were consistent with a progression pathway from LCIS to ILC. Mechanisms of calcium absorption by anterior and posterior segments of the intestinal tract of juvenile lake sturgeon. Angle-closure glaucoma-simpler answers to complex mechanisms: LXVI Edward Jackson Memorial Lecture. Patients who suffer from chronic abdominal pain as a result of postoperative adhesion formation are challenging to treat.

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The main impurity has turned out to be the adhesive glycoprotein, vitronectin. However, conflicting results have been observed that may have been due to the small number of subjects studied, difficulty in obtaining a healthy control group, absence of controlling for confounding factors, or ethical and regional differences among populations. Molecular diversity in chemical databases: comparison of medicinal chemistry knowledge bases and databases of commercially available compounds. A method is shown for deducing the surface area of a pendant drop from the same profile photograph as is normally used to determine interfacial tension. Linear regression modeling to compare fluoride release profiles of various restorative materials.

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Primary cultures of smooth muscle cells were established from the medial layer of guinea pig aorta. The Board does not accredit training centres as this is the responsibility of national authorities.

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We evaluated left ventricular (LV) regional work from a wall tension-regional area (T-A) loop using sonomicrometers in the excised cross-circulated canine left ventricle connected to a volume servo pump. The unique basal stratum of the limbal epithelium exhibited quick proliferation and vertical migration in all eyes. 35S-Sulphate labelling of glycoproteins and glycolipids in rabbit small intestinal brush borders. Immediate and long-term results in endometrioid cystadenocarcinoma were better than in cases of serous one.

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Stromal cell-derived factor-1 (SDF-1) is known to play an essential role in the regulation of stem/progenitor cell trafficking. An extracorporeal complexing hemodialysis system for the treatment of methylmercury poisoning. Households in the Belarussian Republic: the current situation and trends Animals were curarized then tested during controlled ventilation to ensure constant conditions throughout the whole experiment by suppressing the post-vagotomy apneusis.

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When varying concentrations of platelets were incubated with the supernatant of cells previously stimulated with the ionophore A23187, an enhancement of TxA2 release was also observed. Only a small proportion of TNP memory B cells seemed to express the antigen. To improve vaccine coverage, communication and awareness of vaccine preventable diseases in the general community is an important starting point, and all healthcare professionals and public health/social workers can play a key role in this regard. Thirty-five patients out of the 2,000 PCB-poisoned cases that occurred in central Taiwan in 1978 were neurologically studied in 1980.

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Evaluation based on various datasets indicates that the proposed multi-atlas-based multi-image segmentation (MABMIS) framework yields substantial improvements in terms of consistency and accuracy over methods that do not consider the group of target images holistically. The main objective of this study was to assess whether colour preferences undergo further changes during adult life. Diagnosis and management of acute gastric distention following laparoscopic adjustable gastric banding.

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Stretch modulates amiloride sensitivity and cation selectivity of sodium channels in human B lymphocytes. The minimum value is reached after hatching at day 1 in quail, day 4 in chick and day 6 in duck. The formation of antinucleosome antibodies and nucleosome-Ig complexes is a characteristic feature of MRL/lpr mice.

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These results suggest that TCA may play a role in regulating the function of autoreactive lymphocytes of patients with RA. First, microcolumn SEC-CZE is explored as a means of 2-D protein analysis. Assessment of articular hypermobility should be part of the examination in patients with patellar dislocation.

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Here we describe the development of an aging interventions testing program funded by the National Institute on Aging (NIA) to test candidate interventions in a model system. A relationship between the tumor and a hormonal imbalance could not be ruled out.

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In the present study, we demonstrate that primitive progenitors physically separated from the stromal layer by a 0.45-microns microporous membrane continue to generate differentiated progenitors for at least 8 weeks. Characteristics of calcitonin degradation in vitro produced by incubation with procine thyroid tissue. Forty eyes of 20 age-matched normal control subjects were assessed in group 3. The mean efficiencies of utilization of ME for maintenance (km) for the S, E and L silages were 0.69, 0.71 and 0.68 respectively.

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The vessel and ECM composition was examined by immunoblotting and electron microscopy. In summary, this study shows that purified Gln506-FV can account for APC resistance of plasma because Gln506-FVa, whether generated by thrombin or FXa, is relatively resistant to APC.

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Organization was biased by coloration: The drawings were (a) uncolored, (b) colored in ways that emphasized plausible three-dimensional parts of the represented objects, or (c) colored in ways that emphasized two-dimensional (2D) parts of the drawings themselves. The birds were maintained for 28 days, during which time body weight, feed consumption, and oxygen consumption were measured. We sought to determine whether selected clinical or radiologic characteristics can predict the likely etiology of CNS lesions in liver transplant recipients and thus obviate the need for diagnostic brain biopsies. The diagnostic value of multichannel intraluminal esophageal impedance and pH monitoring in gastroesophageal reflux-related cough

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To evaluate whether thyroid autoimmunity and dysfunction, induced by interferon-alpha therapy, could be viewed as predictors for treatment response and as valid prognostic markers of liver disease progression. This article considers current knowledge and future perspectives on the make-up and function of human gut microbiota, with a particular focus on altered microbiota and gastrointestinal disorders, nutritional influences on the gut microbiota, and the consequences for gastrointestinal health, as well as improved understanding of gut-microbiota-brain communication.

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Lithium, valproate and several atypical antipsychotics continue to be recommended as first-line treatments for acute mania. coli isolates suggests a nosocomial dissemination rather than repeated introduction by individual patients into the clinic. The authors describe an incident following the scleroses of the long sapheno-femoral junction. While DsbB, under normal aerobic conditions, is in the oxidized state, having two intramolecular disulfide bonds, oxidation of Cys104 and Cys130 requires the presence of Cys41-Cys44. The number of peptides detected in a limited number of samples and the various combinations of peptides in individual Microcystis colonies highlights the immense metabolic potential and diversity of this genus.

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To determine if the association between frequency of leisure-time physical activity and mortality risk differs across adulthood. Stability of trauma-related symptoms during acute substance use treatment. Diagnostic accuracy analysis of the MRI was performed using varying prostate-subpart sizes and varying cutoffs for the radiological probability for PCa presence. In a hospital-based case-control study including women and men with angiographically documented coronary artery disease (CAD) admitted to a university hospital during a 6-month period, we observed an excessive hereditary predisposition in women. Periarticular cancellous bone changes following anterior cruciate ligament injury.

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For 37 months after operation there has been no recurrence of tumor. These data suggest that ECS may regulate excess activation in central dopaminergic and serotonergic system following forced swimming stress. Originally, communications programs were advanced to meet the need for better participation in development programs by rural people and to facilitate the transfer of technical know-how.

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Ophthalmologists, otolaryngologists, neurosurgeons, and neurologists in the UC healthcare system who are more academically productive receive greater remuneration. Quantitative models of cytoskeletal micromechanics and biochemistry require accurate estimates of local stress and flow conditions.

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Screening in the general population is not recommended, but a high-risk group that is more suitable for screening could be identified, including obese and nulliparous women, those treated with unopposed estrogen or tamoxifen, or those with family or past histories of breast or colon cancer. A large number of proteins that require zinc for their function are involved in diverse cellular processes, including transcription, DNA replication, metabolism, and cell signaling. We describe a patient for whom nonunion after HTO was successfully treated using long-stem TKA with bone graft to have the nonunion site unite simultaneously. Relationships with poly(ADP-ribose) polymerase activity, DNA strand breakage and incorporation into nucleic acids. Three groups of French physicians--pulmonologists (PUs), thoracic oncologists (TOs), and general practitioners (GPs)--were surveyed through a dedicated questionnaire on lung cancer screening.

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This development was carried out for an atmospheric sounding program, which requires pulsed tunable lasers of high average power covering a large spectral range. This study used plasma profiling coupling Proteinchip array with surface-enhanced laser desorption ionization time-of-fly mass spectrometry to search for biomarkers of postoperative sepsis in patients who underwent liver transplantation. We analyzed men who underwent prostate biopsy at our medical center between July 2012 and June 2014. Described in the paper is a flow cuvette (probe) for an optical analyzer of formed blood elements and other cell suspensions. Evaluation of Mycobacterium kansasii isolates from a clinical laboratory in a city hospital

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Just how widespread ancient and/or recent hybridization is in animals and how it affects estimates of species relationships is still not well-known. After retrieval of the full texts, two of the authors independently made decisions concerning the final inclusion and these were validated by the third reviewer. A hazardous materials identification system for the coating and resins industry. Rapidly developed scalar timing in unsignalled shuttlebox avoidance learning.

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