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Detrol (Tolterodine)

Detrol is a prescription medication used to treat the symptoms of an overactive bladder in adults. Detrol belongs to a group of drugs called antimuscarinic medications, which help the bladder muscles to relax. This medication comes in an immediate-release tablet form and is usually taken twice a day with or without food. It also comes in a long-acting capsule form and is usually taken once a day with water. Swallow long-acting capsules whole. Common side effects of Detrol include dry mouth, dizziness, and headache.

Other names for this medication:
Tolterodine, Detrol, Roliten, Detrusitol, Flochek,

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Individuality and mutuality in the language of families of field-dependent and field-independent children. Nevertheless, uniform samplings often generate overlapping data, which can cause false rejections of surrogate data tests. Extracellular recombinant protein production under continuous culture conditions with Escherichia coli using an alternative plasmid selection mechanism.

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The description of the species Trichuris leporis which was given by Tiner (1905) refers to another species for which the name Trichuris tineri is suggested. There also exists a hydrophobic region at the N-terminus which may be part of a cleavable signal peptide.

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Protein kinase C controls lysosome biogenesis independently of mTORC1. Whereas acetylcholine stimulated both rhythmic and tonic (shift of the base line) activity of the tested muscles, lysolecithin induced tonic contractions, but had no influence on the rhythmic activity. The heart failure was cured by resection of the arteriovenous malformation.

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Throughout the region, this lineage is now the predominant genotype of FMDV serotype A sampled, and has appeared to have replaced the A-Iran-96 and A-Iran-99 strains which were previously encountered. The present study compared the efficacy of psychotherapy for childhood anxiety disorders (excluding trials solely treating post-traumatic stress disorder or obsessive-compulsive disorder). Risk of epilepsy/seizures is significantly increased for all classes of antidepressant. Based on a deletion analysis of RID to determine the minimal functional domain, we have identified a subdomain at the N terminus of RID that is homologous to the membrane targeting C1 domain of Pasteurella multocida toxin.

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There were no intraoperative or postoperative complications as a result of this technique. The 1996 pertussis epidemic in New Zealand: descriptive epidemiology. Very prominent peaks centered at 1-1.5ppm were noted in spectroscopic analysis, which probably corresponded to lipid/cholesterol peaks, correlating with the histological findings revealing high amounts of cholesterol in the cyst fluids. After resuscitation and hemodynamic stabilization, a CT angiography was performed to analyze the neck size of the PAPA and its position relative to the branches of the parent artery.

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Various practical observations on the use of heparin in recent myocardial infarction Effect of ethanol extracts from red pepper seeds on antioxidative defense system and oxidative stress in rats fed high-fat . Guidelines for the sociomedical assessment of performance in patients suffering from chronic non-malignant diseases of the liver and the bile ducts - for the medical assessment services of the German Pension Fund

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Much of the 226Ra initially deposited in the skeleton is lost within a few days of its administration. The results indicate that the G-WRM is an appropriate tool for tracking a spectrum of wheelchair-related activities from regular wheelchair propulsion to wheelchair sports such as handcycling. FSa-II subclones as well as both in vitro and in vivo recurrent clones showed a wide variation in thermal sensitivity. Sequential therapy with targeted agents in metastatic renal cell carcinoma: beyond second-line and overcoming drug resistance.

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In the present publication, attention is given first to fertility and infant mortality and then to contraception. Sister-chromatid exchanges are increased in epileptics, but not by sodium valproate. Recovery of the in vitro reactivity of splenic cells of CBA/N mice toward type 2 thymus-independent antigens This suggests that individual vertebra may be susceptible to multiple fractures over the course of the healing process.

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Patients should be monitored for hyperglycaemia upon commencement of high-dose steroid therapy and treatment commenced as indicated. The developed method enables biomedical researchers to automatically and robustly quantify the pro- or anti-migratory effects of different experimental conditions on unlabeled cell cultures in a 3D environment. Cardiovascular risk profile of mothers of a Portuguese birth cohort: a survey 4 years after delivery.

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Bacterial infections during the first months of life remain a significant cause of neonatal mortality and morbidity. The same effect is taken as one of the (possible) basic pathomechanisms not only of epilepsy, but also of some psychiatric disorders., e.g. Studies of lipid profiles showed a marked decrease in the total phospholipid concentration in spermatozoa, primarily in sphingomyelin, phosphatidyl choline and ethanolamine fractions.

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A residual domain 6.5 nanometers by 5 nanometers in size has been found which is inherently stable in saturation fields. Conventional and diffusion tensor MRI was performed on three occasions during the first week of life. Lakoff (current issue) describes an account of conceptual representation based in part on metaphor. Quantitative CEA ELISA, which quantitated changes in total cellular CEA content, demonstrated greater increase in CEA than predicted by cellular ELISA.

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The approximative molecular weight of toxoplasmin -- a skin reactive extract from Toxoplasma gondii -- was estimated by ultrafiltration through different Amicon membranes. He divulged a longstanding history of seborrhoeic dermatitis with frequent flares leading to large volumes of squames collecting on his bed sheets.

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Both typical and atypical antipsychotic drugs are D2 receptor antagonists but yet appear to have markedly different effects upon the induction of dopamine sensitization. Colocalization of NGF binding sites, trk mRNA, and low-affinity NGF receptor mRNA in primary sensory neurons: responses to injury and infusion of NGF. Both effectors inhibited electron transfer to extracellular hexacyanoferrate III. Copper(0)-induced deselenative insertion of N,N-disubstituted selenoamides into acetylenic C-H bond leading to propargylamines. Detection of this diversity adds an important new piece of evidence in the search for the origin of the surface barrier phenomenon.

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As an auxiliary method for amniocytic analysis, it can provide reference for the consultation of those with advanced age and high pregnancy risk. Solid-phase synthesis and investigation of benzofurans as selective estrogen receptor modulators. The purpose of this work was to determine whether cerebral endothelial cells have the capacity to synthesize histamine or to express mRNA of receptors that specifically respond to available free histamine. Morphological and physiological restorations of hereditary form of dilated cardiomyopathy by somatic gene therapy. Our series of 3 patients supports a causal connection between bleomycin and scleroderma.

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In an excess of cholesterol, above 2:1 mol ratio, phase separation takes place into a mixed phase and an almost pure cholesterol phase. Immune system stimulation increases the optimal dietary methionine to methionine plus cysteine ratio in growing pigs. The proposed algorithm does not require a complex learning from a large manually-built training set, as is the case of the existing methods. Bone loss in inflammatory arthritis: mechanisms and treatment strategies. In one location (Lelystad) the strains were thought to lack the ability for inhibited development as a result of environmental stimuli on the infective larvae, while in the other location (Utrecht) this ability was presumed to be present.

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Molecules are linked into a complex three-dimensional framework by a combination of two N-H...S hydrogen bonds, three C-H...F hydrogen bonds and a pi-pi stacking interaction. However, a large clinical trial with long-term follow up is needed to confirm the result. Safety of home and hospital birth--data does not support the conclusions. However, further validation is needed in other settings, and in longitudinal studies to determine its sensitivity to change in cognitive function over time. Ventricular tachycardia was identified in one horse following NBB and xylazine administration.

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In vitro activation by reductants other than 2-mercaptoethanol suggested some selectivity in their access to relevant sulfhydryl groups, but did not reveal which natural redox-sensitive compound might regulate IRF in vivo. The numerical method that is applied calculates islands in tokamaks like the Doublet III-D at General Atomic and the International Thermonuclear Experimental Reactor. Modulating in response to changes in sensory information may be critical to successful foraging in a variety of environments. Acute renal failure--differential diagnosis and therapeutic procedure In some unstable regimes, we observe that the uniform state will evolve toward a radially symmetric attractor with a variable density.

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A computational analysis of the relationship between neuronal and behavioral responses to visual motion. The paper first discusses methodological considerations for a place-based approach and then illustrates the use of spatial analysis techniques as the first step in identifying place-based risk factors in mortality associated with heat waves. Its mechanism might be related with decreasing cholinergic neuron damage and reducing the abnormal activation and hyperplasia of astrocyte. ATP-binding cassette transporters drive the transport of substrates across the membrane by the hydrolysis of ATP.

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This study investigated the first-pass effect (E) and total hepatic intrinsic clearance (Clint) of propranolol and pindolol by means of an isolated rat liver perfusion model. Significantly, there is an obvious spinodal in the variance curve of the inter-particle distances along the increasing cutoff distances, implying a legible transition pattern between the liquid-like and crystal-like aggregations.

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Proteinase inhibitors in ovulation, fertilization and implantation. UV irradiation or alkylation of chromatin cross-linked the active proteins to DNA and prevented their dissociation. We found that this protein shares immunochemical determinants and many other properties with the lipid transfer protein, LTP-I, which has been purified from human plasma.

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In an earlier paper based on PM(2.5) speciation network data, we showed that nickel (Ni) concentrations were much higher in New York City (NYC) than in New Jersey (NJ) and Connecticut (CT), and that the NYC levels, but not those in NJ and CT, were much higher in the winter than in summer. A novel robust index to assess beat-to-beat variability in heart rate time-series analysis. Compared to the general population, NF1 patients have a fivefold risk for cancer and a more than 2000-fold risk for neurogenic malignancies. After taking the drug orally (total dose, 152 g), the first patient developed corneal subepithelial infiltrates and toxic retinopathy characterized by fine pigment mottling of the peripheral fundus and macula with mild arteriolar narrowing.

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However, many people, physicians included, are unaware of the practical aspects of owning a hearing aid. Neutrophil priming by hepatocyte growth factor, a novel cytokine.

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The unresponsive achromic lesions showed poor expressions of both markers. 3rd annual session of the Society for Rehabilitation in Digestive and Metabolic Diseases. The results were also evaluated for correlation with visual acuity and kinetic perimetric measurements. Colorectal cancer (CRC) is one of the most common cancers worldwide. Since the probe itself does not fluoresce but becomes fluorescent upon hybridization to the mature target RNA, it provides a quick and selective way for detection of various forms of RNAs.

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Especially patients who receive primary curative RT and patients who are administered RT after RH, where more pelvic denervation occurs, are at higher risk due to high doses of RT. The degeneration pattern differs significantly from that of embryonic vertebrate neurons. Type I collagen immunoperoxidase staining, radioimmunoassay quantitation, and analysis of type I and III collagens mRNA levels showed an inhibition of collagen production and gene expression. The BCL2L12 protein is composed of 334 amino acids, with a calculated molecular mass of 36.8 kDa and an isoelectric point of 9.45. Pretreatment with actinomycin D or reagents that interfere with the activation of NF-kappaB significantly attenuated the down-regulation of E-cadherin, which implicated a role for the de novo protein synthesis.

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Moderate numbers of these fibers were found in the olfactory bulb, insular, infralimbic and prelimbic cortex, amygdala, ventral, and dorsolateral parts of the suprachiasmatic nucleus, paraventricular nucleus except the lateral magnocellular division, arcuate nucleus, supramammillary nucleus, nucleus of the solitary tract, and dorsal motor nucleus of the vagus. Because BMS-225975 has poor apoptotic activity compared with BMS-214662 but inhibits FT to the same extent as BMS-214662, it is very unlikely that FT inhibition alone can account for the apoptotic potency of BMS-214662.

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Their relationships with both the nuclear membrane and the nucleolus are discussed in the light of their ultrastructural features. The predictability thereof is compared to the Charlson Model and the ICES model. Cardiac transplantation: noninvasive detection of rejection by echocardiography PCP is most evident in cell sheets, and research into PCP was for years confined to studies in Drosophila melanogaster.

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For the diagnosis of the type of tumour, its size, infiltration into the renal capsule, demonstration of regional lymph node metastases and infiltration into neighbouring organs and for the diagnosis of liver metastases, CT was superior to the other methods. This article describes an assessment of saliva biospecimen samples collected through the mail, trial participant demographic and behavioral characteristics, and their association with saliva and DNA quantity and quality.

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size and depth of osteochondral defects, availability of donor autologous grafts, potential for damaging donor sites, the dead spaces between circular grafts and integration of donor and recipient hyaline cartilage. Both fetal and maternal toxicity were noted at 300 ppm and the no observed effect level under these experimental conditions was 30 ppm for both the dams and the conceptuses. TGD2 appears to be anchored with an N-terminal membrane-spanning domain into the inner envelope membrane, whereas the C-terminal domain faces the intermembrane space.

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First principles pseudopotential calculation of electron energy loss near edge structures of lattice imperfections. Here we reported a novel function of URG11 to promote gastric cancer growth and metastasis. Potential underdosing with the use of electron beam therapy in patients with cervical adenopathy and advanced head and neck cancer.

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On 12 farms where only BZ were used, egg hatch discrimination dose testing (EHDDT) was conducted to detect anthelmintic resistance (AR) to BZ. The distinctive characteristics of the neuronal types we have identified suggest that each receives input from different sources and projects to a set of targets that is functionally appropriate. Most emergency nurses have little education on dental conditions yet some new attendances to emergency departments are for dental problems.

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Effects of training and detraining on adiponectin plasma concentration and muscle sensitivity in lean and overweight men. Clinical tests included biometry, corneal topography, pachymetry, and refraction (with and without cycloplegia). It is suggested that St 91 can cross the blood-brain barrier although why no hypotension is observed after i.v. However, very little attention has been given to LA segmentation from three-dimensional (3-D) ultrasound (US), most efforts being focused on the segmentation of the left ventricle (LV). PRELP was also detected in CLL cell-lines (4/4) but not in cell-lines from other hematological tumors (0/9).

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Because palmitoylation regulates PSD-95 membrane targeting, we combined a conformation-specific recombinant antibody against palmitoylated PSD-95 with live-cell super-resolution imaging and discovered subsynaptic nanodomains composed of palmitoylated PSD-95 that serve as elementary units of the PSD. Optimizing Donor Quality Via Hormonal Therapy: An Important Strategy to Increase Successful Placement of Thoracic Organs in End-Stage Patients. Failure to achieve isonatric haemodialysis (HD) drives an expansion of extracellular volume leading to increased interdialytic weight gain (IDWG).

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Beta globulin was slightly increased in both groups, and gamma globulin was decreased in OC users. We conclude that the locus, designated ADH5, encoding the chi isozyme has a separate evolutionary origin from the other ADH genes. Detection of multiple tumor suppressor genes for Syrian hamster fibrosarcomas by somatic cell hybridization. In addition, the peptides Gly-Leu-Pro, Leu- Gly-Pro, Leu-Pro-Gly, Pro-Gly-Leu, Pro-Leu-Gly, Gly- Pro, and Pro-Leu, which consisted of glycine, proline, and leucine, were synthesized by the solid-phase method. Primed subjects responded symptomatically within a period adequate for entry into studies.

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Except for the balancing and running performances of the girls, a fairly linear trend of improvement with age was observed in the motor performances of the groups. On the sagittal dimension, pressure decreases along the palatal midline in an anteroposterior direction. Well-designed, prospective and randomized studies are needed to establish recommendations. Wastewater Mediated Activation of Micromotors for Efficient Water Cleaning. Nisin has now been shown to have antimicrobial activity against both Gram-positive and Gram-negative disease-associated pathogens.

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Characterization and prediction of highway runoff constituent event mean concentration. Real-time coherent object edge reconstruction with Bi(12)SiO(20) crystals. Icotinib and Gefitinib did not induce autophagic flux or inhibit mTOR in A549 cells.

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Role of endogenous peptide in human alloreactive cytotoxic T cell responses. Firstly, the similarities and differences between the binding sites of MMP-2 and MMP-9 were analyzed through sequence alignment and structural superimposition. M-Track provides a valuable and user-friendly interface to streamline the analysis of spontaneous grooming in biomedical research studies. Of those patients undergoing followup cultures 4 to 6 weeks after therapy 72 per cent had sterile urine.

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Methylglyoxal reacted rapidly and reversibly with N alpha-acetylcysteine to form the hemithioacetal adduct. Intraspinal and intracranial fugentin augmentin dose surgical procedures are predicated on nontrauma to the neuraxis. In contrast, isotype-specific RF, which reacted equally well with a and b allotypes of IgG2a, represented the major RF species in one Igh-1a and all five Igh-1b strains tested. The highly polymorphic canine microsatellite ZuBeCa6 is localized on canine chromosome 5q12-q13.

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One of these complexes (complex 1) forms with extracts of both unstimulated and lipopolysaccharide-stimulated macrophages and requires a large fragment of the ARE containing clustered AUUUA pentamers. Administration of activated protein C or antithrombin inhibited local and systemic derangement of coagulation and inflammation following intestinal ischemia/reperfusion, diminished mucosal fibrin deposition, and attenuated ischemia/reperfusion-induced intestinal injury. The receptive-field organization and response characteristics of 79 cutaneous afferent fibers serving the glabrous skin were studied in detail and teva-venlafaxine xr withdrawal definition compared to cutaneous afferent fibers of normal and previously crushed nerves studied earlier.

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Addressing competencies for the future in the professional curriculum. The effects of beraprost Na, a stable prostacyclin analog, on animal models of stroke. Amongst the many advantages that the use of this single currency may bring, there is one that is serendipitous from the viewpoint of studying anomalies in color vision: the eurocent coins serve as a ready-made test to detect anomalous chromatic vision. Stromal cells were cultured for three weeks in the presence of 10(-8) M dexamethasone, 50 microgram/mL ascorbic acid and 10 mM Na beta-glycerophosphate with or without 10 pantoprazole cost uk universities ng/ml LIF or OSM. At each interim analysis both efficacy and futility are evaluated through a specified loss structure together with the predicted power.

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When mycelia with nitrate reductase activity were transferred to ammonia media, there was a rapid loss in the reduced nicotinamide adenine dinucleotide-nitrate reductase activity plus megapen tablet covers the parallel loss of the reduced nicotinamide adenine dinucleotide-diaphorase and the reduced methyl viologen-nitrate reductase activities associated with the nitrate reductase. There was a positive and significant correlation between the dose administered and peak plasma 7-OHMTX. Ecological responses of Brassica juncea-alfalfa intercropping to cadmium stress Although it is often proposed that blockade of voltage-dependent sodium currents is an important mechanism of antiepileptic action of valproate, the exact role played by this mechanism of action at therapeutically relevant concentrations in the mammalian brain is not clearly elucidated. Humoral immunodeficiency due to Dock8 mutation provides evidence that organization of the immunological synapse is critical for signaling the survival of B cell subsets required for long-lasting immunity.

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Some of the hotspot motifs in both yeasts are known or suspected to bind transcription factors (TFs), amoxicillin dose for 3 year old which are required for the activity of those hotspots. In contrast, context-dependent changes in overall eye and head contribution to gaze amplitude were not preserved during SC stimulation. Enhancement of slowly deactivating Kv2 current can account for the increased afterhyperpolarization produced by BK inhibition and likely underlies the very different effects on the f-I relationship. Theoretical issues of gender in the transition from socialist regimes. Shock-induced respiratory insufficiency (clinical aspects, pathology ultrastructure and morphometry)

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In a biological environment, nanoparticles immediately become covered by an evolving corona of biomolecules, which gives a biological identity to the nanoparticle and determines its biological impact and fate. Luciani-Wenckebach phenomenon during clonidine treatment: a case description In rats exposed for 3 or venlafaxine cost 6 months to toluene, m-xylene and their mixtures (1:1) at concentrations of 1000 ppm and 100 ppm, respectively, the observed disturbances in rotarod performance test and decrease in spontaneous motor activity were statistically significant in comparison to control.

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For spermicidal microbicides, additional contraceptive effectiveness studies are also needed. The prognosis of patients with bone metastasis from primary lung cancer is poor, and the effective treatment for bone metastasis had not been established. mode of action of clopidogrel ppt airport A simple method for freezing and maintaining tissue specimens in a mixture of solid carbon dioxide and 95 per cent ethyl alcohol at a temperature approximating -78 degrees C. Earlier use of FSC following an asthma exacerbation was associated with reduced risk of future asthma-related exacerbation and lower use of rescue medications.

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Structural organization of the human gene encoding nuclear lamin A and nuclear noracin information about dogs lamin C. A model, using two harmonic oscillators, reproduces the experimental findings. A relevant animal model is critical for investigating the pathogenic mechanisms underlying hepatitis B virus (HBV)-induced hepatocellular carcinoma (HCC).

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We used continuous-time Markov models based on CD4 cell counts and anti-CD3 reactivity (i.e., measure for T-cell quality) to study the progression of cefixime ofloxacin in pregnancy HIV infection in a cohort study of homosexual men in Amsterdam. The gene encoding F5, termed I2rf5, was mapped using interspecies mouse crosses in close proximity to a number of genes associated with neuronal defects on distal chromosome 4. Fullerene is an acceptor material which is used most usually in organic photovoltaic cell. From bowel to kidneys: the role of cubilin in physiology and disease.