Donaren is an oral antidepressant drug that affects the chemical messengers (neurotransmitters) within the brain that nerves use to communicate with (stimulate) each other. The major neurotransmitters are acetylcholine, norepinephrine, dopamine and serotonin. Many experts believe that an imbalance among the different neurotransmitters is the cause of depression. Although the exact mechanism of action of Donaren is unknown, it probably improves symptoms of depression by inhibiting the uptake of serotonin by nerves in the brain. This results in more serotonin to stimulate other nerves. Donaren is approved for the treatment of major depression. However, it is most commonly used for treating insomnia. Donaren also may increase directly the action of serotonin. Donaren is chemically unrelated to the selective serotonin reuptake inhibitors (SSRIs), the tricyclic antidepressants (TCAs) or the monoamine oxidase inhibitors (MAO inhibitors). It is chemically related to nefazodone (Serzone) and shares its actions. The FDA approved Donaren in 1981.
Other names for this medication:
Trazodone,
Desyrel,
Azona,
Donaren,
Mesyrel,
Nestrolan,
Oleptro,
Reslin,
Trant,
Trazodon,
Trazodona,
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Lenar,
Zotrole,
Aroxin,
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Nizole,
Duomox,
Mirtazapine,
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Sulfametoxazol,
Lanacine,
Uricont,
Biaxsig,
Clindesse,
Pantul,
Technivie,
Hycid,
Tagremin,
Dosier,
Levozine,
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