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In an attempt to identify molecular markers predictive of occult neck metastases, we investigated whether positive p53 or proliferating cell nuclear antigen (PCNA) immunoreactivities on deparaffinized sections of the primary tumor are correlated to the presence of occult neck node metastases in oral tongue cancer patients with clinically negative cervical nodes (N0). An evaluation study of a health education programme for rural women in Bangladesh. Low density lipoprotein metabolism in human fibroblast tissue cultures

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1q21.1 microdeletion syndrome is phenotypically heterogeneous even among members of the same family. It has been suggested that the Clinical Pulmonary Infection Score (CPIS) may help to resolve these difficulties however, its use is questionable. Small size at birth and greater postnatal weight gain: relationships to diminished infant lung function. Proteolysis-inducing factor is expressed in tumours of patients with gastrointestinal cancers and correlates with weight loss.

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SKAP2, a novel target of HSF4b, associates with NCK2/F-actin at membrane ruffles and regulates actin reorganization in lens cell. Migration and the business cycle in the Federal Republic of Germany since the 1960s Particular emphasis will be given to changes in the serotonin system and how these may represent a constitutional risk factor as opposed to a state-dependent risk factor for suicidal behavior.

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Tissue-specific expression of Tirant was detected in the tissues of ovaries in a strain mutant for the flamenco locus. Here, we used naturalistic video stimuli and recorded the spatial patterns of functional MRI signals in human retinotopic cortex to test whether the discriminability of such patterns varied with the presence and congruence of co-occurring sounds. Results showed that Stat1 and Stat2 immunostaining were significantly increased during IFN-alpha treatment. This represents a great advantage when considering adipose tissue as a potential and suitable source of stem cell for cell therapy.

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Image formation by use of the geometrical theory of diffraction. SARMs have been demonstrated to have fewer clinical applications to date, but continue to be investigated for use in multiple disorders in which androgen receptor modulation is likely to be important.

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Synthesis of thermostable geopolymer from circulating fluidized bed combustion (CFBC) bottom ashes. The probabilities of conditioned reflexes elicited by conditional and differential stimuli implicitly contain information concerning excitation vectors that encode the respective stimuli. A smooth muscle nodule producing 10-12 cycle/min regular contractions at the mesenteric border of the pacemaker area in the guinea-pig colon.

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Other aspects to comment are the coexistence with a collagen vascular and an antiphospholipid-antibody syndrome with the higher titles of IgM ACA that we have found in literature. Human interleukin-2 promotes proliferation of activated B cells via surface receptors similar to those of activated T cells. Comparison of six Aspergillus-specific IgG assays for the diagnosis of chronic pulmonary aspergillosis (CPA). In our review of the current literature, this is the first reported case of localized hepatosplenic sarcoidosis with associated serum CA-125 elevation. The activity of the enzyme that has already been secreted to the external medium is partially inhibited by amino acids.

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Idiopathic ventricular tachycardia refers to those arrhythmias that occur in patients without structural heart disease, metabolic/electrolyte abnormalities, or the long QT syndrome. The mothers had an Oral Glucose Tolerance Test (OGTT) within 24 hours after delivery.

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Localization of ubiquitin and ubiquitin cross-reactive protein in human and baboon endometrium and decidua during the menstrual cycle and early pregnancy. Binding of growth factors to their respective receptors results in receptor dimerization and subsequent autophosphorylation on tyrosine residues. Autopsy provides valuable information in the death of healthy children.

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This study of survivors of AML is the largest to date comparing the late effects of patients treated with chemotherapy (CT) with or without irradiation (RT) or CT followed by bone marrow transplantation (BMT). The tracheal epithelial cells proliferated extensively in this medium, forming lobulated structures within the extracellular matrix. These side effects are often associated with prolongation of the QT interval and are mediated via blockade of the human ether-a-go-go related gene (hERG) encoded potassium channel.

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Obstetrical deliveries associated with maternal malignancy in California, 1992 through 1997. 1-0-Alkyl-2-Acetyl-sn-Glycero-3-Phosphocholine (AGEPC) produced dose-dependent (75-500 ng/site) increases in cutaneous vascular permeability (CVP) in rats as measured by extravasation of Evans blue dye. Flow visualisation and Doppler studies performed on anatomically accurate PCG models characterised in vitro anastomotic flow patterns.

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Excisional biopsy revealed a cystic papillary adenocarcinoma of the left submandibular gland, very rare in children. Fourteen patients with inoperable cancer treated with peritoneovenous shunts for malignant ascites were studied post mortem. The Essential Role of Spermidine in Growth of Agrobacterium tumefaciens Is Determined by the 1,3-Diaminopropane Moiety. Loading patterns and jaw movements during mastication in Macaca fascicularis: a bone-strain, electromyographic, and cineradiographic analysis.

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The aim of this research was to study the cotherapeutic effect of stem cell transplantation and gene transfection on chronic venous thrombosis. We report on a case of villoglandular papillary adenocarcinoma in a 26-year-old woman. The bolus injection of ovine LH (10 micrograms, i.v.) at this time caused a significant increase in oestradiol, androstenedione and testosterone, these responses being inversely related to the titre of LHRH antiserum in the plasma at this time. gingivalis, which may be an important factor in the pathogenesis of periodontitis. Parallel to ICAM-1 gene expression data, TNF-alpha-induced monocyte-mesangial cell adhesion was inhibited by PTK inhibitors, but was not regulated through either PKC or intracellular cAMP-associated pathways.

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Several possible experimental detection methods of topological quantum phase transition are proposed. Serum cholesterol levels and the intake of total fat were not related to clinical gallbladder disease in this cohort. In order to determine if monitoring hormone levels and sperm status in the same male over time might increase the sensitivity of detecting a toxic reaction, the second protocol was employed. Five lengthy unassigned intergenic sequences are present, four of which vary in length from 79 to 119 nucleotides and the largest of which is 1.2 kb. Inguinal hernia repair is one of the most frequently performed operations.

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The ERalpha protein detection by this proposed method is based on immuno binding from sample volume as low as 50 nL. Somatostatin receptor scintigraphy in the differential diagnosis of meningioma. However, little is still known about the natural levels of variation and the evolutionary causes of differences in brain size and brain structure within-species, even though selection at this level is an important initial generator of macroevolutionary patterns across species. Studies selected were reviews and longitudinal studies (intervention and cohort) published between 1 January 1966 and 31 October 2012. This study suggests that Type III penetrating trauma may be successfully managed conservatively with a similar outcome to those patients with Type III blunt injuries.

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The diversity of tissues involved, the variety of attributes required to fully describe textural properties, and the changes in these attributes as the product ripens and senesces contribute to the complexity of texture measurement. The relevance of these results to CD1 function as well as to Paneth cell biology is discussed. Lack of a diagnostic gold standard, limited patient follow-up, and uncertain generalizability are limitations. The highest amounts of GM-CSF (up to 2.8 ng/10(6) cells) were produced by MAC that had been derived from MO cultured under serum-free conditions in the presence of 0.5 mg/ml albumin as the only medium supplement. The pathophysiology of these effusions is through the passage on the enzymes by the lymphatic route, by the oesophageal and aortic route or by a pancreatico-pleural fistula.

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Future research on social motivation and interaction will profit from identifying the particular incentives that are salient in a giving setting. Some evidence in favor of collagen production by mesenchymal and/or inflammatory cells leading to a progressive fibrous replacement of the glial cells in this particular tumor type is presented. Then main therapeutic problems are on-off phenomena, end-of-dose akinesia and levodopa-induced dyskinesias.

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Multidrug-resistant pneumococci may be expected to change the way in which primary and secondary care is currently administered. Despite the fact that association between winter birth excess and schizophrenia in the northern Hemisphere is well established, possible sex or birth-cohort differences in this winter birth excess remain unclear. SRY normally requires two distinct NLS-dependent nuclear import pathways to reach sufficient levels in the nucleus for gonadal differentiation. Trauma to the kidneys may be managed by complete nephrectomy, partial nephrectomy, renal capsule repair and temporary nephrostomy.

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Perspective taking in older age revisited: a motivational perspective. With this new method, naso-tracheal intubation under endoscopic control in all 16 patients was successful, without affecting the pharynx and the vocal cords. Risk Factors for De Novo Mixed Urinary Incontinence and Stress Urinary Incontinence Following Surgical Removal of a Urethral Diverticulum.

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Osteoarticular mycobacterium tuberculosis (TB) can present as a subtle insidious infection. The pre- and postoperative (1, 7, 11, and 20 months) hormonal controls are analyzed, indicating the persistence of HGH anteropituitary activity, even though surgical sectioning of the pituitary stalk was performed and the activities of thyroid, corticoadrenal and gonadotropin functions decreased. In brain and retina, stimulation with excitatory amino acids (EAA) can generate nitric oxide (NO) and increase levels of cyclic guanosine monophosphate (cGMP).

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Cells derived from the placenta have become the focus of extensive research concerning their ability to be used for regenerative medicine or cellular therapies. The absorption cross section of colloidal quantum dots in close-packed monolayers shows a 4 (CdSe) to 5-fold (PbS) enhancement compared to quantum dots in a dilute dispersion. The splanchnic vasodilation is associated with a hyperkinetic systemic circulation, with reduced arterial pressure and peripheral resistance and increased cardiac output. Indexes of lipid and glucose homeostasis were determined enzymatically, by ELISA and/or histologically. The present study highlights the utility of residual dipolar couplings for orienting protein domains or macromolecules with respect to each other.

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Models constructed from the experimental data for each tonotopic region demonstrate that the tonotopic tuning measured in NL can improve ITD encoding across sound frequencies. The number of organisms decreased and the granulomatous character of the lesions became more prominent as the disease progressed. The present approach, using genetic manipulation of the immune system, may have relevance to the study of disease mechanisms in other putative autoimmune demyelinating disorders such as multiple sclerosis. This provides a potential for the prevention and management of hepatic fibrosis. The endoscope was advanced and photographs were obtained for review.

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Transfusion of prion-filtered red cells does not increase the rate of alloimmunization or transfusion reactions in patients: results of the UK trial of prion-filtered versus standard red cells in surgical patients (PRISM A). The bidirectional mammalian promoter for mitoribosomal protein S12 (Mrps12) and mitochondrial seryl-tRNA ligase (Sarsm) contains an array of four CCAAT boxes separated by 34-49 bp. Thus, the method may have application in low-current defibrillation devices. Commissioning diabetic eye screening by optometrists: a local initiative at the primary-secondary care interface.

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These results suggest that in general there was a significant improvement in log-likelihood when using RPNB compared to a fixed parameter negative binomial baseline model. The aim of this study was to identify copy number variations (CNVs) with a clinical significance for ASD. Contrast media-induced effects on blood rheology and their importance in angiography.

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An apparent discrepancy between these two approaches is discussed and removed. A blended learning experience that combines traditional practices and e-learning was implemented to teach microbiological methods to pharmacy students. In the 1st hour after fertilization, the fertilized eggs consume oxygen at about 53 or 54 per cent of this rate, which is about 1.3 mm.(3) O(2) per hour per 10 mm.(3) eggs at 21 degrees C. Pre-analytical variables have been shown to exert a profound effect on protein profiles, irrespective of true biological variation.

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As triploidy is associated with increased obstetric complications, fetal karyotyping should be offered to confirm the diagnosis so that appropriate obstetric intervention can be instituted. According to their staining pattern astrocytes were classified into 4 cell types: Type I cells were seen during the non-proliferating period, Type II cells during the low-proliferating period, Type III cells during the moderate-proliferating period and Type IV cells during the high-proliferating period. Comparative expression of Cbf genes in the Triticeae under different acclimation induction temperatures. An adjacent open reading frame is not transcribed under our experimental conditions. Active thrombopoiesis is associated with worse severity and activity of chronic GVHD.

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The authors are confident, however, that drug misuse and polypharmacy can be reduced in older persons by the use of current knowledge of risk factors associated with polypharmacy and by improved communication between the physician and patient. Abnormal left atrioventricular valve dynamics, characterized by a decreased closing velocity of the left atrioventricular septal cusp and increased valve thickness, were observed in 2 of the 4 aged dogs, using echocardiography. A plastic surgery method in vast defects of the anterior abdominal wall Thrombopoietin, TPO, a 353 amino acid cytokine, is a primary regulator of platelet production that was cloned recently. The present study compares two different weight reduction regimens both with a moderately high protein intake on body composition, serum hormone concentration and strength performance in non-competitive female athletes.

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It has been proposed that gliomas arise from the subventricular zone in mice during development. The added utility of the two variables was then examined using multiple logistic regression. An important, but frequently overlooked, aspect of validating health outcome measures is to establish if items exhibit differential item functioning (DIF).

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Basic insight into the charge adjustment process is obtained by using a self-consistent-field lattice theory for polyelectrolyte adsorption. Basic principles and clinical advancements of muscle electrotransfer. The women who are addicted to illicit drugs during pregnancy, have an increased risk for infants with several congenital defects.

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To know the epidemiologic features, clinical manifestations and etiology of puerperal endometritis in our environment in addition to the use of endometrial cultures in the microbiologic diagnosis of this infection. Their distribution between the traditional and PBL curricula was equal. A new procedure for treatment of oily slurry using geotextile filters. Binding studies, autoradiography, and RT-PCR of AT2 revealed that the AT2 content in granulosa cells was time dependently increased at both protein and mRNA levels in equine chorionic gonadotropin-treated immature female rats. Three cases of Legionnaires disease caused by Legionella longbeachae Sg 1 associated with potting compost have been reported in Scotland between 2008 and 2009.

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This study investigates the feasibility of utilizing silastic gages for in vivo dynamic muscle force measurement. Abnormal activity of corneal cold thermoreceptors underlies the unpleasant sensations in dry eye disease.