Fexodine is a hydrochloride salt form of Fexodine, a carboxylated metabolic derivative of terfenadine and third generation selective histamine H1-receptor antagonist with antihistaminic and non-sedative effects. Fexodine competitively binds peripheral H1-receptors, thereby stabilizing an inactive conformation of the receptor. Consequently histamine binding and activity as a result of mast-cell degranulation followed by the release of multiple inflammatory mediators, such as interleukins, prostaglandin and leukotriene precursors, is blocked, thereby preventing the triggering of pro-inflammatory pathways.
Other names for this medication:
Fexofenadine,
Aerodan,
Allerfex,
Allerstat,
Altiva,
Axodin,
Drusa,
Feksine,
Fenadex,
Fenadin,
Fenax,
Fenixa,
Fexidine,
Fexo,
Fexodine,
Fexofast,
Fexofen,
Fexofenadin,
Fexofenadina,
Fexotabs,
Histafree,
Histaloc,
Nefoxef,
Rinolast,
Telfast,
Telfexo,
Xergic,
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Caluran,
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Efexor,
Borbalan,
Difluzol,
Tamsul,
Cotrimstada,
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