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Ketozal (Ketoconazole)

Ketozal is an imidazole antifungal agent. Ketozal has oral tablet, cream and dandruff shampoo formulations. The oral formulation is available in USA since 1981. Ketozal is the only member of the imidazole class that is currently used for treatment of systemic infections. Ketozal is a highly lipophilic compound. This property leads to high concentrations of Ketozal in fatty tissues and purulent exudates. Expectedly, the distribution of Ketozal into cerebrospinal fluid is poor even in the presence of inflammation. Its oral absorption and solubility is optimal at acidic gastric pH. While Ketozal was more widely used before the development of newer, less toxic, and more effective triazole compounds, fluconazole and itraconazole, its use has now been limited. It now appears as an alternative drug for specific indications.

Other names for this medication:
Ketoconazole, Nizoral, Akorazol, Arcolan, Arcolane, Asquam, Biogel, Clarazole, Conazol, Daktagold, Daktarin, Dezor, Diazon, Dikoven, Eumicel, Extina, Funginoc, Fungoral, Ilgem, Kenazol, Kenazole, Ketazol, Ketokonazol, Ketolef, Ketovid, Ketozal, Liondox, Lizovag, Micoral, Micosin, Muzoral, Mycoderm, Noell, Orifungal, Oronazol, Panfungol, Perative, Phytoral, Pristinex, Tiniazol, Tinuvin, Xolegel, Yucomy, Zoloral,

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To construct a subtractive cDNA library from the spinal facets of adolescent idiopathic scoliosis (AIS) patient with suppression subtractive hybridization (SSH) technique and clone differentially expressed genes related to AIS in spinal facet. (2) Pfizer has been granted marketing authorization in the EU for a powdered insulin product for pulmonary inhalation, for the treatment of adults with type 1 or type 2 diabetes. Structure of adsorbed n-dodecyl-beta-D-maltoside layers on hematite. Most biological information is contained within gene and genome sequences. Indeed, large amount of nitric oxide (NO) are produced at sites of inflammation through the action of NOS-2.

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Two cosmids that hybridized with two Alu-PCR products were further characterized. A 72-year-old Japanese woman presented with early-onset motor and sensory neuropathy associated with scoliosis, deformities of the hands and feet, and carpal tunnel syndrome. HN-30 cell infected with microRNA-223 overexpression vector showed a significant increased in microRNA-223 expression, whereas HN-30 cell infected with microRNA-223 inhibitor vector suppressed microRNA-223 expression.

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Steady-state binding of adenine nucleotides ATP, ADP and AMP to rat liver and adipose plasma membranes. Detection and clinical study on coronavirus HKU1 with acute lower respiratory tract infections of hospitalized children in Changsha

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Data collected were husbandry system, anamneses, physical examination findings, surgical treatments, and postoperative results. In ketamine-anesthetized rats, the bilateral microinjection of the alpha(2)-receptor antagonist yohimbine into the RVLM significantly reduced the enhanced levels of urine flow rate (V) and urinary sodium excretion (UNaV) produced by xylazine.

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Gamma radiation tolerance of a tropical species of midge, Chironomus ramosus Chaudhuri (Diptera: Chironomidae). These results indicate that yeasts adapted to wine give results similar to those that occur in wine during ageing.

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Human retinal pigment epithelium (RPE) contains two genetically distinct forms of superoxide dismutase (SOD) enzymes that scavenge harmful superoxide anions. Improved outcomes were seen with the most aggressive intervention, home nursing, and medical neglect referral, but not with less aggressive measures. Tissue transplantation was used to correct the depression deformity. The treatment of surgical sepsis: current modes and new horizons.

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Understanding the molecular events of embryo-maternal interaction is of interest to reproductive biologists, clinicians and couples affected by infertility. Neutrophil numbers were determined on uncentrifuged urine, and IL-8 levels were measured by ELISA. However, owing to the sensitivity of organic moieties to solvents and temperature, device processing is challenging, particularly for patterning. The effect of an applied mechanical stress on the tunneling conductance of a ferroelectric tunnel barrier between substrates and dissimilar electrodes is studied. Sixty-one consecutive iliac arteries in 59 patients with long occlusions in 16, occlusions of the common iliac in 11, occlusions of the external iliac in 24 and multiple stenoses of the iliac in 10 cases underwent semiclosed recanalisation through a groin incision.

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High body temperature may promote clot lysis whereas low body temperature is neuroprotective in patients with cerebral infarction. Adipogenic differentiation of mesenchymal stem cells on micropatterned polyelectrolyte surfaces. Amorphous zirconium oxide nanoparticles were synthesized by a simple and low-cost hydrothermal process, and their phosphate removal performance was explored in aqueous environment under various conditions. This research protocol was approved by the institutional review board of each participating institution, and all participants provided written informed consent. The construction of the common iliac nodes individually varies within the interval the fragmented--focal types.

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Multicomponent adsorption on activated carbons under supercritical conditions. We present here a family with a previously undiagnosed X-linked condition characterized by progressive restriction of joint range of motion, prominence of the supraorbital ridge, audiology issues and hernias.

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Expert opinion: Multidrug targeted approaches are set to emerge, given the heterogeneity of osteosarcoma subtypes and the multitude of therapeutic responses. Two-dimensional transport-induced linear magneto-resistance in topological insulator Bi2Se3 nanoribbons. The main causes for requests were fetal anomalies and late application. In addition, these studies demonstrate subtle differences in bactericidal activity at various concentrations of the antimicrobial agents, which cannot be determined by agar or broth dilution methods.

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The effect of thalidomide on experimental tumors and metastases. Bone tunnel widening after anterior cruciate ligament reconstruction using EndoButton or EndoButton continuous loop. Previous reports combining gonococcal stomatitis and central papillary atrophy of the tongue were not found during a thorough review of the world literature. Constructing Bayesian networks by integrating gene expression and copy number data identifies NLGN4Y as a novel regulator of prostate cancer progression. These cellular transitions take place in a stepwise manner and are regulated at the transcriptional level.

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Beside their function in cellular growth processes, polyamines and particularly putrescine play a role in calcium-related events at the cell membrane, coupling an extracellular stimulus to an intracellular response (second messenger-like reactions), modulate the calcium-buffering capacity of mitochondria (spermine), and, if present in the extracellular compartment, modulate the activity of the N-methyl-D-aspartate receptor (spermidine and spermine). This image can be used during surgery to perform a variety of maneuvers that would otherwise require a contact prism, high-minus contact lens, or handheld indirect ophthalmoscope lens. Hemostatic variables as independent predictors for fetal growth retardation in preeclampsia. Two other characteristic aspects in HIV-1 infection, metabolic syndrome and lipodystrophy, will be evaluated in light of activity of interleukin 18.

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Protein-Protein Interactions in DNA Recognition: H-NMR Studies of Lambda cI Repressors Genetically Altered by Site-Directed Mutagenesis. Poor left ventricular function and pleural effusion frequently shown on chest X-ray film complicated the postoperative course.

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The finding of glucose-stimulated Na absorption has proven to be therapeutically useful: the rate of intestinal fluid loss can be decreased in certain forms of diarrhea by oral administration of electrolyte solutions containing glucose. After the withdrawal of the Russian army, the country is being torn apart by fighting bands of extremists. Compensatory development of immature LH cells after long-term gonadectomy: an immunocytochemical, electron microscopic and cell count study. The more acidic isoforms of FSH are found in hypogonadic patients and a displacement towards the basic forms is observed during substitutive treatment. Exercise-Induced Release of Pharmacologically Active Substances and Their Relevance for Therapy of Hepatic Injury.

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