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Long-term behavioral changes were observed in high-LET carbon ion-irradiated mice. In this initial experience resection was restricted to patients with bronchogenic carcinomas of less than 6 cm in diameter who had no involvement of the mediastinum.

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In conclusion, this study, for the first time, shows that fluvastatin might affect melanin synthesis in vivo. Our case is the Quattro Study, a pragmatic trial on the effectiveness of multidisciplinary patient care teams used in primary health care centres in deprived neighbourhoods of two major cities in the Netherlands for intensified secondary prevention of cardiovascular diseases. Biomechanical interaction between cap thickness, lipid core composition and blood pressure in vulnerable coronary plaque: impact on stability or instability. Thus, the microenvironment provided by uterine fluid, particularly glandular secretions, is essential for implantation. Elucidating the pathophysiology underlying the increases in TEMP and PLT and the decreases in ST height may help to explain the etiology of FM.

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Prevalence of A-to-G mutation at nucleotide 3243 of the mitochondrial tRNA(Leu(UUR)) gene in Japanese patients with diabetes mellitus and end stage renal disease. Development of the clinically anti-inflammatory drugs are also warranted. Munc13-4 interacts with syntaxin 7 and regulates late endosomal maturation, endosomal signaling, and TLR9-initiated cellular responses. Bending properties and transformation temperatures of heat treated Ni-Ti alloy wire for orthodontic appliances.

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A 63-yr-old woman with systemic lupus erythematosus (SLE) diagnosed 12 mo previously and treated with prednisolone and cyclophosphamide presented with recent fever and dyspnoea. This investigations demonstrate that the mellitus-syndrome is not only a complex neuroendocrine disturbance but also a disturbance of biogenic amines and the organ of the connective tissue. These results suggest that vitronectin can contribute to the control of cell-surface plasmin activity by regulating the synthesis of urokinase and directing the localization of urokinase receptors. When the parasites were incubated with bacterial phosphatidylinositol phospholipase C (PI-PLC) prior to detergent solubilization and phase separation neuraminidase activity was predominantly recovered in aqueous phase, rather than in the pellet and detergent phase.

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All these results are compatible with an evolutionary analysis of reproductive decision-making. The putative causes of reduced cell number in the floral meristem and the consequences for floral development are discussed.

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Field trials of brodifacoum (WBA 8119) against the house mouse (Mus musculus L.). Does coping mediate the relationship between personality and cardiovascular health in African Americans? THE ROLE OF IODINE IN THE INHIBITION OF THE METAMORPHOSIS OF THYMUS-FED SALAMANDERS. The authors provide validation and technique of circadian phototherapy of bronchial asthma. We suggest an alternative approach, based on measuring the actual velocities of the bars by using fiber-based velocity interferometry.

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The translation and membrane integration of bacterio-opsin from Halobacterium salinarium were investigated. The symptoms of Clostridium difficile infection are mediated primarily by two toxins, TcdA and TcdB, the expression of which is governed by a multitude of factors including nutrient availability, growth phase and cell stress.

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The newly revised Regulations for the Administration of Adverse Drug Reaction Reporting and monitoringhas been implemented since July 1, 2011. Thus ATP and AA can be added to the list of neuroactive agents that control glycogen levels in astrocytes, which includes noradrenaline, vasoactive intestinal peptide (VIP), adenosine and histamine. This study investigates a specific method for making possible the participation of participants with cognitive and communicative impairments in social face-to-face interaction. The regimen with additional 1,25(OH)2D3 did not considerably influence learning of the maze task.

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Based on the oxygen effect a new therapeutic modality has been developed to protect healthy tissues while breathing hypoxic gas mixture during irradiation. Effects of bromocriptine on growth hormone secretion and adult height prediction. Full-fat sitostanol ester-containing margarine reduces serum total and LDL cholesterol, but the effect of plant stanol ester-containing margarine as part of a low-fat, low-cholesterol diet has not been studied. Treatment of status asthmaticus in medical practice and in the hospital

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These results suggest that interruption of the autocrine IL-6 loop would be of therapeutic value in SLE. BK virus DNA was detected in all neuroblastomas and none of five normal adrenal glands by PCR. It can, however, reassure anxious patients of the absence of arrhythmia during symptoms.

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(1982), in which metatarsals are cultured with various tissues that act as sources of osteoclast precursors. Since extracapital blood vessels in osteonecrotic femoral heads showed mild changes and the head of osteoarthrosis showed no vascular changes, the authors conclude that arteriopathy is a specific and primary condition in early ONFH and is implicated in the pathogenesis of ONFH. Based upon these features, the Tradescantia micronucleus bioassay was established. We describe an in vitro culture process that uses 100-microm diameter poly(ethylene terephthalate) monofilaments as contact guidance of human umbilical vein endothelial cells (HUVECs) to orient the development of microvessels in a 3D environment.

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The exact place of helical computed tomography in such sequential algorithms remains to be established. Many individuals with intellectual disabilities experience challenges to participating in organized sport, despite its known benefits.

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At the same time, new concepts in melanoma care are discussed, including sentinel lymph node mapping, immunotherapy, and melanoma vaccines. Epilepsy is a clinical, not an EEG, diagnosis, but the EEG, when used appropriately, can greatly aid the diagnostic process. The authors propose an economic model capable of simulating the 4 main historical stages of civilization: hunting, agricultural, industrial, and postindustrial. A third group of symptoms, comprising various delusions and hallucinations, was associated with poor figure-ground perception, and might reflect temporal lobe dysfunction.

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Micronucleus induction in gill cells of green-lipped mussels (Perna viridis) exposed to mixtures of polycyclic aromatic hydrocarbons and chlorinated pesticides. We developed Willows in a user friendly interface with the goal of maximizing the use of memory, which is critical for analysis of genomic data. We have investigated the source of this space-mapped auditory activity by using retrograde tracing with horseradish peroxidase. Endocavitary removal of catheter fragments which had migrated into central cardiac cavities The pathophysiology and the clinical and laboratory presentation of patients with this disease entity are reviewed.

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Interleukin-6 (IL-6) does not change the expression of Bcl-2 protein in the prevention of cisplatin-induced apoptosis in ovarian cancer cell lines. Acute respiratory distress syndrome (ARDS) is a clinical syndrome of severe dyspnoea of rapid onset, hypoxemia, and diffuse pulmonary infiltrates leading to respiratory failure in the absence of cardiac failure. Current methods of selecting PEEP only provide a range of values and do not provide unique patient-specific solutions.

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Nailing the coffin shut on doubts that violent video games stimulate aggression: comment on Anderson et al. Accurate assessment, measurement, and exploration of acculturation of Filipinos in the United States can help improve the overall health care of this population. These observations help us understand the pathophysiology of nasal conditioning, but do not negate the positive clinical benefits of budesonide on treating nasal inflammation. Tumor cells have been reported to generate unique cancer volatile organic compound (VOC) profiles which can reflect the disease conditions. Further increases in heart rate resulted in reductions of cardiac output and stroke volume.

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Effect of various immunization procedures on the primary and secondary antibody responses to bovine serum albumin. Current hepatitis B virus infection situation in Indonesia and its genetic diversity. The urokinase plasminogen activator receptor associated protein (uPARAP)/Endo180 is a novel endocytic receptor that mediates collagen uptake and is implicated to play a role in physiological and pathological tissue-remodelling processes by mediating intracellular collagen degradation. Primary structure elements responsible for the conformational switch in the envelope glycoprotein gp120 from human immunodeficiency virus type 1: LPCR is a motif governing folding.

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Experience to date indicates an incidence rate of approximately 1 per 1,000 per year of cancer in the upper respiratory and alimentary passages among males more than 45 years old who are heavy cigarette smokers. We describe zebrafish with mutations in two APC/C subunits, Cdc16 and Cdc26, whose phenotypes reveal a multifaceted set of defects resulting from the gradual depletion of the APC/C. In the present study we characterized the developmental changes in the prevalence of mRNA coding for microtubule-associated protein, MAP1B, embryonic alpha-tubulin and late neural beta-tubulin in rat hippocampus and forebrain from 1 to 720 days of age using RNA gel-blot analysis. The presence of E2R is correlated with patient age at diagnosis and tumor grade but not with the presence of metastatic foci in axillary lymph nodes. A guide to utilization of the microbiology laboratory for diagnosis of infectious diseases: 2013 recommendations by the Infectious Diseases Society of America (IDSA) and the American Society for Microbiology (ASM)(a).

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We retrospectively compared an earthquake-exposed cohort of 215 thoracic trauma crush victims of the Sichuan earthquake to a cohort of 215 non-earthquake-related thoracic trauma patients, focusing on the lesions and coexisting injuries to the thoracic cage and the pulmonary parenchyma and pleura using a multi-detector CT. Diabetic nephropathy (DN) refers to the structural and functional changes in the kidneys of patients with diabetes mellitus (type 1 or 2).

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The author uses mathematical models to analyze the divorce rate in Czechoslovakia for the period 1982-1987, with an emphasis on regional differences. Since RAD6 and its mammalian homologs can ubiquitinate histones in vitro, we have investigated the pattern of histone ubiquitination in mouse testis. Thus, at present, analysis of cannabinoids, tropane alkaloids, ketamine as well as psilocin (N,N-dimethyltryptamine derivative) is well-managed. There is increasing evidence that a tumour comprises of heterogeneous population of cells.

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A case of chronic subdural haematoma after epiduralanalgesia in obstetrics is described and possible pathomechanisms are discussed. In this paper we discuss a normal mixture model for the observed change in the characteristic of interest in treated patients. Painful extraskeletal osteochondroma under the tarsal sesamoid: a case report and review of literature. Since the development of inclusion and integration, parents have increasingly become the major, and sometimes the only, carers of their children with disabilities. There were positive smooth muscle and endothelial cells for all five SSTR subtypes, the highest proportions being SSTR1 and the lowest SSTR5.

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These results indicate therefore that the alteration in HA is the direct consequence of exposure to an adverse low pH and provide further support for the conclusion that the M2 protein, the target of amantadine action, is involved in regulating vesicular pH, a function important for the correct maturation of the HA glycoprotein. Grease, anthraxgate, and kennel cough: a revisionist history of early veterinary vaccines. How can a work rehabilitation process be improved?--a qualitative study from the perspective of social insurance officers.

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Dilutional acidosis: is there a role for the strong ion difference? Focus on the experiences of people recovering from mild traumatic brain injury may help to refine recovery models and understandings and thus provide more effective intervention targets.

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NMR studies showed that the 22 positively charged residues (Lys(18) and Arg(4)) are distributed into three clusters on the surface of hRNase7. Dissolution studies were carried out according to the USP XXII paddle method for 14 h. Psychiatric symptoms and cognitive dysfunction caused by Epstein-Barr virus-induced encephalitis. On this conceptual basis, a dozen different bond types in diatomic molecules will be analyzed in the following article. Newly diagnosed patients with lymphoma are at risk of low BMD, which may worsen with therapy.

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Modulation of ryanodine-induced contractures in human skeletal muscle pretreated with dantrolene. Together, these findings demonstrate that CPE binds to the hydrophobic turn and flanking polar residues in the loop 2 of claudin-3 outside tight junctions. Data quality monitoring must address the entire process by which the data are gathered, transmitted, stored, and analyzed. We have used monoclonal antibodies raised against isolated native calf thymus centrosomes to probe the structure and composition of the pericentriolar material. Uncommon metastatic sites include the liver, adrenal gland, kidney, pancreas, and skin.

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Rapidly cycling SCs function principally during normal tissue maintenance and are highly sensitive to stress, whereas qSCs exit from their quiescent state in response to homeostatic imbalance and regenerative pressure. Both short-term and long-term exposure HIA tools were applied with regard to the appropriate data for Silesian voivodeship.

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A 3-month interval between OC use and a planned conception is recommended. Thus, organ-specific colonization by tail-vein-injected murine F9 teratocarcinoma cells shows a particular pattern: unselected, undifferentiated F9 cells preferentially colonize the liver of the syngeneic animal.

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At 6 h after pleural injection, the mean blood WBC count and percentage of neutrophils were significantly elevated in the TL group, whereas the mean LDH and IL-8 levels were significantly increased in the SN group. Evaluation of the haemostatic profile in the pre- and post parturient mare, with particular focus on the perinatal period. It is more acceptable to parous women who plan to continue practicing contraception. The role of an immune response in the failure of bioprosthetic heart valves is poorly understood and disregarded by many.

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Syllable repetition was slightly better than vowel prolongation for differentiating the vocal behaviors of aged and young speakers. Clinical significance of EBP50 overexpression assessed by quantum dot analysis in gastric cancer. parous users, and raised incidence of pelvic disease are discussed. Biochemical basis of the constitutive repressor cleavage activity of recA730 protein.

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Here we propose a hierarchical Bayesian model, BASIS (Bayesian Analysis of Splicing IsoformS), to infer the differential expression level of each transcript isoform in response to two conditions. Here we explored the effects of intranasal administration of exogenous recombinant human Hsp70 (eHsp70) on lifespan and neurological parameters in middle-aged and old mice. We examine four different problems in order to perform a comparison between several recently proposed methods and, finally, conclude by identifying limitations and future challenges in this field. The number and types of samples are changed to investigate the effect on HTR parameters.

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Differential density gradient ultracentrifugation procedures, utilizing a vertical rotor, were developed for the preparative purification of very high density lipoproteins (VHDL, density greater than 1.21 g/ml). Cellular and molecular basis of increased ammoniagenesis in potassium deprivation. Deletion of Suv4-20h1 reduces fHC and induces transcriptional activation and repositioning of the MyoD locus away from the heterochromatic nuclear periphery. In addition, a disulfide bridge between subunit 4D54C and subunit 6 was evidenced, thus demonstrating near-neighbor relationships of the two subunits and a location of the N-terminal part of the mitochondrially-encoded subunit 6 in the intermembrane space. Lymphocyte function associated antigen-1, integrin alpha 4, and L-selectin mediate T-cell homing to the pancreas in the model of adoptive transfer of diabetes in NOD mice.

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Percentages are in accordance with the international literature. Mechanisms of control of skin blood flow during prolonged exercise in humans. The Th1/Th2-like switch in syphilitic infection: is it detrimental?

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Prevention of Pneumocystis carinii pneumonia and of cerebral toxoplasmosis by roxithromycin in HIV-infected patients. Elevating motions from the hanging position and the 90-degree elevated position, respectively, were tested in two directions of the sagittal and scapular planes: the results showed better motions in the scapular plane. In mutant mice, lacZ was expressed in place of tenascin, and no tenascin product was detected. Regulatory T cells (Treg) can induce and maintain antigen-specific immune tolerance and facilitate allogeneic graft survival successfully in animals.

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A glucan from an ectomycorrhizal edible mushroom Tricholoma crassum (Berk.) Sacc.: isolation, characterization, and biological studies. The ancestry of genes taken from these species can also be represented as a tree, with the branching points representing ancestral genes. Responses to inspiration and abdominal compression were also analysed. Basal TAFI and CLT in patients with APS having an adverse or a good obstetrical outcome were similar.

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Appropriate use of anti-infective drugs is essential in clinical practice. English abstracts of proceeding of the twentieth congress of the Japan Society for Cancer Therapy. If the two fields are equal in area and brightness but different in flicker frequency, the number of animals going to the two fields is proportional to their flicker frequencies.