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In this study, different recombinant baculoviruses that expressed varying fusion proteins of the CPV VP2 protein with the T cell determinant and/or the linear virus-neutralizing epitope of rabies virus (RV) were generated. Evaluation of a multiplex panel of immune-related markers in cervical secretions: a methodologic study. Obesity is a critical health concern that has captured the attention of public and private healthcare payers who are interested in controlling costs and mitigating the long-term economic consequences of the obesity epidemic.

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Serum retinol, alpha-tocopherol, and lipid peroxide concentrations in low-income indian pregnant mothers. Urinary tract infection is the most common hospital-acquired infection, and a common complication of urinary catheterisation. Purulent pleurisy in a specialized hospital environment in Bamako

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Temporal trends in the population structure of Bordetella pertussis during 1949-1996 in a highly vaccinated population. Predictors of coronal caries progression in adults: results from the Prevention of Adult Caries Study. SV40 Immortalization of feline fibroblasts as targets for MHC-restricted cytotoxic T-cell assays. The ratio of HPMC and CMC-Na, the viscosity of HPMC and the different types of the diluents had pronounced effect on the release of GBE sustained release tablets, although the hardness and weight difference of tablets did not show notable influences.

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Although FISH is one of the most important physical mapping techniques, research on the resolution of FISH on different cytological targets is scarce in plants. Fatty acid-derived lipid mediators and blood platelet aggregation.

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A broad range of extracellular proteins secreted by Pseudomonas aeruginosa use the type II or general secretory pathway (GSP) to reach the medium. One hundred and fifty-five patients were included in this prospective open comparison study. Detailed rates of acute toxicity and skin infection during total skin electron beam therapy (TSEBT) for mycosis fungoides have not been reported in a large, modern series.

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We have developed a laser Doppler velocimeter (LDV) for measuring velocity distributions in blood vessels. Clinical application of sentinel lymph node biopsy for staging, treatment and prognosis of colon and gastric cancer. Postoperative short survival was related to tumor sequence DNA alterations on chromosome 2, 11, and 21. Clinical evaluation of the Bionic Glove, a prototype of a new functional electrical stimulation device designed to improve the function of the paralyzed hand after spinal cord injury.

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Making borders stick: population transfer and resettlement in the Trans-Curzon territories, 1944-1949. They also blocked increased startle after a series of footshocks, provided they damaged the most anterior part of the basolateral nucleus. These mechanisms are distinct from those processes of arousal that produce the background EEG desynchronization of waking. Casemix differences were significant, and accounted for approximately 77 per cent of the difference in costs between providers.

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The erythrocyte water channel functional size was shown to be 30 kDa, and is identical to the size found in rat renal proximal tubule brush border membranes (1), suggesting close homology of these two water channels. Although the prevalence of HIV behavioral risk factors has been well documented, few researchers have chosen to investigate the impact that psychopathology may have on HIV risk behavior. HGF mRNA level in the cells was increased to 4-fold higher levels at 6 h after exposure to IL-1 alpha. 1569 individuals (ages 58-89) answered a questionnaire on cosmic transcendence in two cycles of the Longitudinal Aging Study Amsterdam in 1995-1996 (time 1) and 1998-1999 (time 2). In this study, we quantify expression of ERalpha and ERbeta in human monocytes and macrophages.

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Paralog genes arise from gene duplication events during evolution, which often lead to similar proteins that cooperate in common pathways and in protein complexes. An analytical method for the determination of perfluorinated compounds in whole blood using acetonitrile and solid phase extraction methods. Additionally, inhibition of NHE1 resulted in ERK inhibition as well.

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It is suggested that some of the GAGs participate in the creation of a storage depot for biologically active molecules (growth factors, enzymes) which are thereby stabilized and protected. The methodological aspects and problems with the study are discussed. Vinculin is abundant in the intercalated disks and in myotendinous junctions but occurs also at the peripheral sarcolemma in the form of a regular repeat of dots and of fine bar-like extensions into the cytoplasm from the dots. The requirement was also estimated by fitting the Reading model to data for growth rate and methionine intake.

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A cholecystectomy was carried out and histology of the gallbladder revealed a marginal zone lymphoma. Differential diagnosis of cancer in fine-needle biopsy aspirates using the transmission electron microscope.

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To investigate the growth and development of brain derived neurophic factor(BDNF)-positive neurons in the frontal lobe of human fetus. In this issue of the JCI, two independent research groups report novel observations in mouse models of severe SMA that provide hope that this approach will afford meaningful benefit to individuals with SMA.

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Nevertheless, pretreatment with the therapeutic dose of garlic for ten days induced a prophylactic activity against the pathogenic effects of the venom in both tissues, which appeared more or less normal except for very minor abnormalities. p27(Kip1) removal requires a preliminary ubiquitination step due to the Skp2-SCF E3 ligase complex.

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We estimated LCI in the patients with Duchenne muscular dystrophy (DMD) and Kugelberg-Welander disease (KW). Once regarded as an inert lining, the vascular endothelium is now known to synthesize a variety of molecules that can protect against or promote disease. The eyes were examined ophthalmoscopically and histologically at 30 min, 6, 24 h, 2, 3, 4 and 5 days after the insult. Painless myocardial infarction in diabetics has traditionally been attributed to damage of cardiac pain fibres by autonomic neuropathy but other factors such as microangiopathy in the myocardium may be responsible. To predict an abnormal electroencephalography, interleukin-16 and 10-minute Apgar used in combination performed better than current markers.

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Stimulus-related and saccade-related activity was reduced on anti-saccade trials. Chromatin immunoprecipitation assays showed that Rb repressed hPygo2 by inhibiting Elf-1 at the Ets-binding site in the hPygo2 promoter. No major differences in the levels of hepatic and intestinal apo B and apo E mRNA occurred between control and copper-deficient rats. Prostatic intraepithelial neoplasia (PIN): morphological clinical significance.

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Polistes-mastoparan-R1, 2, and 3 (Pm-R) were tetradecapeptides that possess high sequence homology with that of mastoparan. FXIII, with its unique role as a transglutaminase among the other serine protease coagulation factors, is now recognized as a multifunctional protein involved in regulatory mechanisms and construction and repair processes beyond hemostasis with possible implications in many areas of medicine.

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This study evaluates the response of the gastric mucosa to pentagastrin in a group (HAG) of 17 andean subjects compared to a similar group of 17 subjects at sea level (LAG). In particular, surface-adherent biofilms and bacteria living within protozoa pose potential health problems that are unrecognized by conventional laboratory culture methods. Aortic stenosis (AS) is one of the most common valvular disorders affecting the aging US population.

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Time characteristics of brain stem acoustic evoked potentials and acoustic reflex of the intra-aural muscles were measured in workers with occupational hypoacusis having normal and delayed capacity for speech discrimination. Reconstituted PMP29 showed cytochrome c reductase activity and O2(-). Esophagogastric junction (EGJ) pressure is the major barrier to gastroesophageal reflux.

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The ratio of k3 in tumors to k3 in tumor-free brain was also significantly related to histological tumor grade. An unstable haemoglobin, Hb Tacoma beta30 (B12) arg leads to ser, detected at birth by the demonstration of red cell inclusions. High tumour interstitial fluid pressure (TIFP) is a characteristic of most solid tumours. Both patients have shown no evidence of metastatic disease throughout their follow-up.

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Nocturnal Cheyne-Stokes respiration (CSR) occurs frequently in patients with chronic heart failure (CHF), and it may be associated with sympathetic activation. A diagnosis of dermatomyositis was established by the characteristic skin changes together with a muscle biopsy. To compare the expression of genes playing a decisive role during the embryonic development of the female genital tract (WNT4, WNT5A, WNT7A, PAX8) in the peritoneum of patients with endometriosis and control patients.

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Ligand design by-pam: A ruthenium-catalyzed asymmetric arylation of aldehydes with arylboronic acids has been developed, giving chiral diarylmethanols in good yields. (III) Flanking fragments from the N- and C-termini of progastrin that do not contain any primary gastrin in their sequence, but nevertheless may undergo posttranslational processing.

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The search for novel ways to target and alter the genomes of living organisms accelerated rapidly this decade with the discovery of CRISPR/Cas9. Protein kinase C (PKC) is a multigene family of serine/threonine protein kinases involved in cell signaling pathways of proliferation and motility. Adherence to physical activity recommendations in a hypertensive primary care population

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We suggest that temperature coupling may often arise due to a common effect of temperature on song and preference, rather than be an advantageous characteristic whose function is to maintain coordination in temperature-affected communication systems. TNF blockage produces a comprensible reservation in patients with risk factors for cancer. The addition of the third dataset identifies a large number of additional injuries and demonstrates the error of using only the two main sources for injury data. Using highly purified or monoclonal cellular reagents we demonstrate that macrophages (M phi) stimulated with supernatants from activated T cells release large amounts of neopterin into culture supernatants. The study is of great importance regarding both fundamentals and applications.

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Importance of caudal mesenteriography for precise determination of the degree of spread of rectal cancer and for the choice of treatment method A multicenter study was conducted to evaluate the diagnostic accuracy (sensitivity and specificity) of the Verigene Gram-Positive Blood Culture Test (BC-GP) test to identify 12 Gram-positive bacterial gene targets and three genetic resistance determinants directly from positive blood culture broths containing Gram-positive bacteria. The Mood Disorder Questionnaire (MDQ) is a widely used self-report screening instrument for the detection of bipolar disorder in clinical populations. Development of multi-residue methodology for the HPLC determination of veterinary drugs in animal tissues.

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Oral immunization of dogs with purified cholera toxin, crude cholera toxin, or B subunit: evidence for synergistic protection by antitoxic and antibacterial mechanisms. Examination findings included visual acuities of 20/20 (1.0) to 20/500 (0.4), defective color vision, mild to moderate myopia, pericentral or centrocecal scotomas, and, in four of five patients, optic atrophy. Post-occlusive hyperaemic peak flux was decreased in patients with incipient nephropathy relative to the other diabetic patients, which suggests a defect in maximal arteriolar vasodilatation. Originally orthodontists and surgeons worked more or less separately from each other. This action of the guaiacol ion is in marked contrast to the behavior of other anions whose effect resembles that of Cl(-).

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Our report highlights the role of echocardiography in the detection of myocardial ischemia and apical PSS as a marker of ischemic memory. The effect of a commercial deproteinized blood extract--on motility of human spermatozoa was examined in vitro.

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However, there are certain objections to assigning a preeminent role to this helical bundling in the tetramerization reactions. The mitochondrial permeability transition pore is a recognized drug target for neurodegenerative conditions such as multiple sclerosis and for ischemia-reperfusion injury in the brain and heart. This article analyses the difficulties faced in the importation of this urban-developed treatment model into a rural setting. In addition, another group on long-term contraceptives was investigated.

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An area for further research should be to explore the significance of including serum potassium in prognostic models. Old-age socio-economic and financial circumstances as measured by wealth are associated with grip strength, particularly among the least wealthy, while circumstances defined earlier in life as measured by education, income and occupation do not consistently predict grip strength. Comparison of mechanisms after post-hoc analyses of the drotrecogin alfa (activated) and antithrombin III trials in severe sepsis. A dimensional approach focusing on common phenomenological and neurobiological substrates is suggested as particularly useful for clinical management and future research of both disorders.

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Quality of life appears increasingly as fundamental criteria in the assessment of treatment outcomes. The potential ability of Acinetobacter to transfer resistance plasmids to other strains is of particular danger for distribution of resistant microorganisms in hospitals. These results substantiate the unreliability of self-report on smoking status in the pregnant population and in women who are recent quitters. Pinpoint obstructive stenosis of the urinary stoma was treated in 5 patients after ileal conduit urinary diversion and in 2 with cutaneous ureterostomy. This lack of valuable information has created many challenges in the care of the critically ill patient as intermittent hemodialysis drug dosing recommendations cannot be extrapolated to CRRT.

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This study reports clinical results obtained by different departments in the treatment of chronic leg ulcers by cryopreserved cultured allogeneic epithelium. Renal cortical slice accumulation of p-aminohippurate (PAH) and tetraethylammonium (TEA) was decreased in the normoglycemic group. They also showed adipogenic, osteogenic and chondrogenic potentials similar to MSC populations from other sources as already described in the literature. Deficient transcription of mouse mast cell protease 4 gene in mutant mice of mi/mi genotype. The PCDD/F homologue patterns of all surface soils were consistent with each other.

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Several of these proteins have been characterized at the molecular level and their role in latex allergy has been elucidated. In FISH, an appropriate cut off value should be settled for each probe or procedure in estimating chromosomal gain, loss, or translocation and the sensitivity depends on the cut off values but it may reach to 10(-3). These data demonstrate that these two genes are similarly regulated in two cells of the nervous system, further suggesting that the oxidative state of a cell may dictate a neurotoxic or neuroprotective outcome. Effects of preterm delivery were substantial on both language production and comprehension at 18 months. Stepwise methodology for plain radiographic assessment of pedicle screw placement: a comparison with computed tomography.

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HLA-DP molecules function as restriction elements in the presentation of foreign antigens to T cells by antigen presenting cells and certain HLA-DP molecules confer susceptibility to autoimmune disease. Walls of capillaries showed a heavy precipitation of fine fibrillar material admixed with collagen fibers.

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By using standard saponification techniques and derivatization of the acids to their p-bromophenacyl esters, it is possible to differentiate them by high-performance liquid chromatography. A better understanding of these mechanisms may provide new therapeutic strategies to prevent HIV infection.

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The proliferation and migration/invasion of H441GL cells were inhibited by ACAE in a dose-dependent manner. Probabilistic finite element analysis of the uncemented hip replacement--effect of femur characteristics and implant design geometry.

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Bidirectional allosteric modulation of strychnine-sensitive glycine receptors by tropeines and 5-HT3 serotonin receptor ligands. QSAR studies on the basis of multiple linear regression analysis showed that with increasing lipophilicity of the substituents on the amine moiety, the statistical significance of the indicator variables, denoting the substitution pattern on the central aromatic ring system, also increases.

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aegypti transmits DENV by inoculating virus-infected saliva into host skin during probing and feeding. The optical absorption spectra of nanometer-thick organic films and molecular monolayers sandwiched between two metal contacts have been measured successfully using surface plasmon resonance spectroscopy (SPRS). We recommend this strategy for faith-based practices and residencies with 1 practice site, but further research is needed on multisite practices and to achieve higher influenza vaccination rates. They have the same mother who had a normal cerebral imaging study.