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During high-intensity dynamic exercise, O2 delivery to active skeletal muscles is enhanced through marked increases in both cardiac output and skeletal muscle blood flow. In this national prospective surveillance study of IFIs in HSCT recipients, the cumulative incidence was highest for aspergillosis, followed by candidiasis. A retrospective review of consecutive patients treated with intracranial stents at 5 institutions was performed.

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Cytokine-regulated expression of E-selectin, intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1) in human microvascular endothelial cells. The aim of the present survey was to assess the management of fungal infections in these units in France. Gelatin given by vein to doubly depleted dogs (anemic and hypoproteinemic) gives no immediate toxic response, no anaphylactoid reactions, and may contribute something to the building of new hemoglobin and plasma protein. At the age of three month purely breast-fed babies are significantly lighter and show less weight gain since birth than purely bottle-fed ones. (2) To determine the availability and cost of adequately iodized salt at the retail shops.

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Binding capacity of blood 25-hydroxyvitamin D-binding protein in man Western immunoblot analysis showed that mAb G3A5 was directed against a single polypeptide with an apparent molecular mass of 138-kDa (p138 antigen). In vitro differentiation of embryonic stem cells demonstrated that endothelial cells derived from wild-type and Foxo1-deficient embryonic stem cells were able to produce comparable numbers of colonies supported by a layer of OP9 stromal cells. Collectively, these results showed that YvcC is a multidrug ABC transporter functionally active in wild-type B. During meiotic prophase, telomeres cluster, forming the bouquet chromosome arrangement, and facilitate homologous chromosome pairing.

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One hundred and three patients undergoing ovarian stimulation with a fixed dose of 200 IU recombinant FSH and GnRH antagonist. Using appropriate optical magnifications, even very small, newly-formed vessels are recorded. FUS recruitment is mediated by the arginine/glycine-rich domains, which interact directly with PAR.

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Potentially malignant lesions and conditions of the mouth and oropharynx: natural history--cellular and molecular markers of risk. acute hepatitis, and a course marked by multiple organ dysfunction syndromes and exitus in a previously apparently healthy individual. It is well know that leukemias with specific molecular abnormalities display profoundly different global gene expression profiles. Weight changes during nutritional counseling by mail using the Nutrition Counseling System-evaluation of 518 participants during a 6-month-long counseling phase Although varying one uncertain factor created enormous variation in the size of the epidemic, it is remarkable that for most preventive strategies the relative effectiveness of the strategies was barely altered.

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This review outlines the association of obesity with risk of colorectal cancer and the potential underlying mechanisms from an epidemiological perspective. As observed with the sequence of a type-II helical segment a model constructed on 3.6 residues per turn of helix shows a line of hydrophobic residues along the helix, thereby supporting the physicochemical evidence that the molecule is predominantly helical and forms part of a coiled-coil structure. Combination treatment with UFT and DP shows promise for clinical cancer.

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We employed network meta-analysis to examine the risk of mortality and hypoglycemia associated with different glycemic control targets in critically ill adults. Cardiac magnetic resonance (CMR) imaging could be superior to echocardiography in a number of ways: for example, for assessing ventricular dimensions, volumes, function and mass, for quantifying valvular regurgitation, and for investigating areas of myocardial fibrosis and extracardiac structures.

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The study was conducted at the Hands On Philippines Education (HOPE) clinic in Bagong Barrio, Caloocan, Philippines. Involvement of cyclooxygenase-2 in hyperplastic gastritis induced by Helicobacter pylori infection in C57BL/6 mice.

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become rapidly useless with decreasing number of data available. The future of carbon dioxide for polymer processing in tissue engineering. Intercellular exchanges of membrane patches (trogocytosis) highlight the next level of immune plasticity. Beating heart valve surgery with lung perfusion/ventilation during cardiopulmonary bypass: do we need to break the limits?

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EFFECT OF THE FORMATION OF INERT PROTEIN ON THE KINETICS OF THE AUTOCATALYTIC FORMATION OF TRYPSIN FROM TRYPSINOGEN. Fenton processes and biological treatments have long been used as common technologies for treating wastewater and polluted soil but they still need to be modified because of some defects (high costs of Fenton process and long remediation time of biotreatments). This is an open source software and freely available for download. To evaluate the assessment criteria and the results achieved in the detection of breast lesions at mammographic screening.

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Two-channel auditory steady-state response (ASSR) recording at high and low MF (modulation frequency) most likely provides an insight about the response amplitude and latency from different directions at the brainstem level and at the thalamus or cortical level. Balloon dilatation of strictures of the upper and lower gastrointestinal tract With the use of a questionnaire-based survey, we examined the prevalence of symptoms that reflect sleep disorders such as insomnia, restless legs syndrome (RLS), and snoring and use of hypnotic medications in 252 hemodialysis patients. Some of the pups reared in isolation from maternal and sibling contact and kept on 12:12 LD cycles, feeding cycles, or combinations of feeding, temperature, and LD cycles also showed rhythmic activity but it was less persistent and of a lower amplitude than the rhythms of the mother-reared group.

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Research was carried out on the genotoxic effects (induction of micronucleated cells in primary root tips) and toxic effects (reduction in primary root growth) in young plants of Vicia faba grown in soils with different organic matter contents and treated with the herbicides atrazine, glyphosate and maleic hydrazide. Exploring the role of insect host factors in the dynamics of Trypanosoma cruzi-Rhodnius prolixus interactions. Venlafaxine (Effexor): concerns about increased risk of fatal outcomes in overdose. This review highlights the clinical validity of endurance measures as inexpensive diagnostic tools for diseases affecting multiple organ systems and evaluating the impact of therapeutic modalities, such as ERT for MPS VI. An educational package was used to introduce the AO classification of pelvic fractures and teach the registrars how to classify pelvic fractures using pelvic X-rays and computed tomography scans.

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Both ambivalence and fear of intimacy were negatively related to self-report and daily measures of social support and to well-being. The lower seroprevalence of HHV-8 relative to that of the other herpesviruses suggests that HHV-8 is less transmissible than other common herpesviruses.

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The virulence of VdNUC-2 defective mutants was significantly compromised, and that was unable to be restored by exogenous application of extra Pi. On the basis of the various determinations, an IM dose of 2.5 mg of gentamicin/kg given every 8 hours should provide therapeutic serum concentrations of gentamicin in the 3 species. The cells of CG-SH are immature blasts and have an immature myeloid phenotype (positive for myeloperoxidase, CD7, CD34, CD38, CD117, HLA-DR, negative for CD10, CD19, CD20, CD41, CD42).

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The promise of canonical Wnt signaling modulators in enhancing bone repair. 1alpha-hydroxycholecalciferol: a promising therapeutic approach for renal osteodystrophy.

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Among nondeployed Soldiers, Combat Arms MOS were only slightly more likely to receive medical disability than Other MOS, and no substantial differences in medical conditions were noted between the two MOS groups. The expression of the combined antibody TRalpha1 and 2 and TRalpha1 or 2 alone as well as the expression of combined TRbeta1 and 2 and TRbeta1 or 2 alone was investigated with specific monoclonal or polyclonal antibodies in 82 patients.

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None of the NP tested significantly affected lysosomal membrane stability, indicating the lack of a major toxic effect. Stochastic and deterministic analysis of reactions: The fractal case.

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In vitro analyses on the proliferation, migration/invasion, cell cycle and apoptosis were performed on ACAE-treated non-small cell lung cancer cells, H441GL and control CGL1 cells. However, there existed no rigorous theoretical work to elucidate how the valve works and consequently to predict the valve-bursting condition. The use and impact of online evidence should be interpreted in the context of nursing practice and culture. In contrast, no synergism was observed between IFN-gamma and mitomycin C. Novel type of phase transition in a system of self-driven particles.

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The mean concentrations of RNA and of SH-groups and the Fisher information exponent were calculated in different zones of the pyramidal neuron cytoplasm zone of the apical dendrite and that of the axon departure. Studies on survivin over the past 5 years have shown that survivin participates in the genesis of several human cancers, including bladder cancer. Structural characteristics of the system of dynamic observation of the health status in the population under ambulatory care

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Impact of 111In-CYT-103 on the surgical management of patients with ovarian cancer. Our results thus show that time of death and delays in enucleation and freezing significantly influence DA and its metabolite concentrations in retinas of rats and humans. This study provides baseline data for future assessment of the impact of HPV vaccination programs. Use of the mucolytic agent, mucosolvin, in multiple modality treatment of cystic fibrosis in children

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In a subset of CM1 patients, epilepsy occurs in the context of neurodevelopmental disorders that also include mental retardation, autism and somatic dysmorphisms. One hundred and ninety patients received an anterior-posterior-glide Low Contact Stress mobile-bearing prosthesis in one knee and a rotating-platform Low Contact Stress mobile-bearing prosthesis in the contralateral knee. Fluorescence continued to increase slightly for up to 7 h even after transfer of the cells to ammonium medium. Partial cross activity was clearly demonstrated in immunoprecipitation experiments in the five subgroups. The ethanol intoxication was prolonged for two years and resulted in a progressive decrease in the level of the pancreatic non secretory phospholipase (p less than 0.01).

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Current trends indicate that the late effects of genetic damage due to exposure to environmental factors are becoming a population problem. The changes in aortic length reached statistical significance after 12 months. The aim of this study was to compare two orthopaedic therapeutic methods: skin traction versus immediate reduction.

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The treatment of cardiovascular disease has considerably evolved over the past 20 years, resulting in a reduction in cardiovascular mortality among the general population. The degradative process involved in the remodelling has also been assessed by immunohistochemistry with anti-metalloproteinase (MMP-1 and MMP-9) and anti-tissue inhibitor (TIMP-1) antibodies. A modulatory role for clathrin light chain phosphorylation in Golgi membrane protein localization during vegetative growth and during the mating response of Saccharomyces cerevisiae.

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Vasoreactive pattern of the brain was almost the same as that of the finger. Experiencing abuse during childhood affects the psychological well-being of individuals throughout their lives and may even influence their offspring by enhancing the likelihood of an intergenerational transmission of violence. Any variation in the formation and/or branching pattern of ansa cervicalis or hypoglossal nerve can cause confusion and may complicate the procedures involving this nerve such as skull base surgery, neck dissection, and anterior cervical spinal approach. Inhibin alpha subunit mRNA expression is not affected by TGF beta. Eligible patients taking dasatinib and with confirmed stable deep molecular response were enrolled between April 1, 2011, and March 31, 2012.

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Variational calculation of the energy levels for the td micro ion. Glutathione and GSSG form the principle redox buffering system in the cell, with the endoplasmic reticulum (ER) being more oxidizing than the cytoplasm. Using these hepatic changes as an adverse effect, the maternal no observable adverse effect level for this study was identified at 300 mg/kg/day. Optical amplification using raman transitions between spin-singlet and spin-triplet states of a pair of coupled in-GaAs quantum dots. In this small series, abciximab had a thrombolytic effect on established thrombi that were refractory to previous antithrombotic treatment attempts.

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Compounds were not included if they were exclusively phytotoxic or if they were isolated from active extracts but were not determined to be the active component of that extract. Plasma adiponectin concentrations were measured and the associations of adiponectin with waist circumference and BMI were analyzed. Randomized controlled trial of a synthetic sealant for preventing alveolar air leaks after lobectomy. Popliteal cysts: sonography evaluation after arthroscopic treatment The study examined the efficacy of daily zinc supplementation in restoring night vision of pregnant women who developed night blindness while routinely receiving either vitamin A, beta-carotene, or placebo in a field trial.

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Cyclic loading did not significantly change the level of vertical misfit. Stimulation of brown adipose tissue activity in tumor-bearing rats. The integrative aspects of cardiac physiology and their implications for cell-based therapy. Parallel microtubules were connected in rows, and then became crystallized in the tail. Given the importance of DNA-dependent protein kinase (DNA-PK) for DNA repair, cell cycle progression, and survival, we hypothesized that it modulates ERalpha signaling.

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Total nitrogen removal in a two-step MBfR system incorporating sequential nitrification and hydrogen-driven autotrophic denitrification was investigated in order to achieve nitrogen removal by autotrophic bacteria alone. This concept is strengthened by the finding that the gene is overexpressed frequently in independently transformed rat ovarian surface epithelial cells.

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To investigate the determinants of paravalvular leak (PVL) occurring after transcatheter aortic valve implantation (TAVI). Glucose detection and concentration estimation in feline urine samples with the Bayer Multistix and Purina Glucotest. or s.c.) on the behavioral responses elicited by intra-accumbens injection of graded doses (1-10,000 ng) of apomorphine and two doses (10 and 100 ng) of melatonin was investigated in rats. Furthermore, we introduce a general, state-resolved pumping scheme which enables control over the optical gain spectrum. Age-related changes in cholesterol and bile acid metabolism in rats.

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One of the twelve femoral heads analyzed at four weeks and six of the twenty-six femoral heads analyzed at eight weeks had severe disruption of the growth plate that precluded histological assessment of the growth plate zones. Nonaccidental head trauma (NAHT) is a major cause of death in infants. Eight articles met the inclusion criteria of this review in the form of one case series, one case study, one survey, two randomized controlled trials (RCTs), one randomized patient and observer blinded cross-over trial, one single blind cross study design, and one self-reported impairment questionnaire. The noncrosslinked collagen mesh Surgisis showed the best behavior in that it induced fewer adhesions. Conditions associated with low leaf water potentials (Psi) have been shown to induce reddening in many plant species.

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Leflunomide prevents proliferation of activated lymphocytes by inhibiting dihydroorotate dehydrogenase, a critical step in de novo pyrimidine synthesis. Magnetic resonance imaging in the diagnosis of canine inflammatory myopathies in three dogs. Manifesting pediatric carrier of isolated dystrophinopathy with initial presentation of myalgia and persistent hyperCKemia. In both experiments, low-span participants performed poorly when task switching from antisaccade to prosaccade blocks. A small amount of radioactivity was distributed into the fetus and the maximum level in the fetus was attained in 1 approximately 4 hours after administration, much later than in maternal tissues.

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Our goal was to evaluate the impact of a single 40 mg kg-1 dose of praziquantel on anaemia. Mice were infected intraperitoneally with trypomastigotes of the Brazil strain of T. Redistribution between fractions of certain lactate dehydrogenase (LDH) isoenzymes is observed: the fraction of LDH4--5 increases and that of LDH1--2 decreases, and the ATPase (EC 3.6.1.3) activity lowers as well.

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Pulmonary fat embolism in a preterm infant receiving Intralipid intravenously is described. The purpose of the present investigation was to verify the role of the epithelium in the functional response of the rat vas deferens.

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Mlvi-1 contains at least one open reading frame which is conserved among species and which preliminary evidence indicates may be expressed in the thymomas. Anterior cruciate ligament injuries occur frequently in athletics, and anterior cruciate ligament injury prevention programs may decrease injury risk. The radish (Raphanus sativus L.) is an important root vegetable crop with fleshy taproots as the edible parts. The lung is the primary organ likely to be exposed by inhalation studies and, therefore, measurement of changes in lung function are of particular interest to the pulmonary physiologist and toxicologist. Preplanned meta-analysis of individual trials with deliberately introduced heterogeneity may maximize the generalizability of results from randomized trials.

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Several previous studies has demonstrated functional roles of miRNAs in antiviral defense mechanisms. Levels of immunoglobulin G antibodies against defined epitopes of the L1 and L2 capsid proteins of human papillomavirus type 6 are elevated in men with a history of condylomata acuminata. It is suggested, given the complexity of drug disposition in vivo, that simplicity in modeling is a desirable goal.

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A total of 151 pancreas transplant needle biopsy specimens from 57 patients were evaluated. The importance of taste and palatability in carbohydrate-induced overeating in rats. PCC 6803, the mutation L66A causes oligomer instability and reduced chaperone activity in vitro. Evidence for natural transmission of Trichinella spiralis spiralis from domestic swine to wildlife.

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Evidence of a Christmas spirit network in the brain: functional MRI study. Polysialylation of NCAM is developmentally regulated and associated with neural regeneration and plastic processes, as well as learning and memory. Ciprofloxacin and clindamycin did both alter neural function in the isolated superfused bovine retina. Mild to incapacitating symptoms have been reported in occupants of urea formaldehyde-insulated homes. As a first step in dissecting the csrRS signal transduction pathway, we determined the mechanism by which CsrR mediates the repression of its target promoters.

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Electron microscopy of cells infected with nonsense mutants of bacteriophage phi 6. The goal of this study is to describe secondary hyperparathyroidism in extremely low birthweight (ELBW) neonates and their response to enteral calcium carbonate (CaCO(3)) supplementation. A comprehensive relational database of three-dimensional structures of nucleic acids. The LPH promoter contains binding sites that mediate activation by members of the GATA-4, -5, and -6 subfamily, but little is known about their individual contribution to LPH regulation in vivo.

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The presence of the two isoenzymes in the culture medium appears to reflect two distinct secretory processes. Chronic lymphocytic leukemia (CLL) terminating in multiple myeloma: report of two cases. Cation selectivity of light-sensitive conductance in retinal rods. The obstetric performance and pregnancy outcome in 208 massively obese patients who were delivered over an eight-year period were compared with those of nonobese control subjects. A case of a de novo astrocytoma in a patient on long-term immunosuppression for psoriatic arthritis is described.

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The authors describe a rare case of congenital splenic cyst, observed in a 22 year old female. The expected performances of the scanner, based on our measurements and on simulations, are given.