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The transcriptional rate of the alpha-tubulin gene was unaffected by the drug. Amyloid formation is a hallmark of several systemic and neurodegenerative diseases.

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The values of the catalytic constant (kcat) were obviously decreased by the substitution of His49 with glutamic acid or the addition of Gly273. The purpose of this study was to evaluate whether children less than 2 years old admitted to the cardiac intensive care unit require a higher enoxaparin dose than that currently recommended to achieve target anti-factor Xa levels. To develop nanoparticles for broad applications, potential risks to human health and the environment should be evaluated and taken into consideration.

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There is no evidence, however, to show that routine ventilation of all transplant recipients provides outcomes that are as good as those documented in extubated patients. A new methacrylic fructose glycomonomer is synthesized and copolymerized with N-isopropyl acrylamide by reversible addition fragmentation chain transfer (RAFT) poly-merization. When the e-SPE portal is completed, the options for summative assessment will be examined as a medium for international certification in conjunction with local and national requirements (http://espe.elearning.nl).

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Enterovirus 71 (EV71), a member of the Picornaviridae family, may cause serious clinical manifestations associated with the central nervous system. Natural selection of the Pol gene of bovine immunodeficiency virus. We report on the experimental observations of multiple dissipative solitons in a passively mode-locked fiber laser with large normal cavity dispersion.

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Introduction of 10(8) pfu of these viruses into the adult rat cerebellum by stereotactic injection yielded neural cell-type-specific expression without apparent toxicity to the animals. What do electrocardiographic and echocardiographic changes during cesarean delivery mean? A computational model of the nicotinic acetylcholine binding site.

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Functionally independent components of the late positive event-related potential during visual spatial attention. Both putrescine and spermidine levels fell within the expected nanomolar ranges and were significantly elevated in the brain of suicide completers with a history of major depression as compared with controls. Small-dose of ketamine does not seem to be a useful adjunct to remifentanil-based anaesthesia during short, painful surgical procedures.

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A sublingual sufentanil tablet is being developed as a potential alternative to intravenous (IV) opioids for the management of postoperative pain. Polygenic Scores in Epidemiology: Risk Prediction, Etiology, and Clinical Utility.

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Reduced expression of CCNT2 may play a key role in the developmental programming of adipose tissue. The psychosocial effects of rheumatoid arthritis on the patient and the well partner. The aim of the study was to investigate the occurrence and effects of overhanging amalgam restorations in young adults. In this study we have used fluorescence spectroscopy to determine the post-mortem interval.

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The accurate intact M(r) together with the pI fraction, and peptide map serve to tag the protein for future interlysate comparisons. Seed-specific expression of truncated OsGAD2 produces GABA-enriched rice grains that influence a decrease in blood pressure in spontaneously hypertensive rats.

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Indirect, or systemic, delivery is limited by factors affecting the concentration gradient across the gastric mucosa and the permeability of the mucosa. Although community members held some dangerous health beliefs (e.g., that malaria can be treated by cupping and blood-letting), this misinformation was addressed respectfully and cautiously, and new ideas were presented in a style relevant to the agrarian culture. The caudate-putamen and frontal cortex contained the lowest activities. Effects of colestipol, clofibrate, and placebo on plasma lipoproteins of patients with hypercholesterolemia. Differential performance of learning disabled and non-learning disabled children on the McCarthy scales, WISC-R, and WRAT.

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Relationship between infant mortality and fertility in seven Asian countries Progressive transformation of germinal centers: review of histopathologic and clinical features.

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They have different responses to treatment that seem to be related to variable C1-INH consumption. Markers may soon help us identify invasive lesions at higher risk of recurring and thus more suitable for adjunct therapy. The protective ability of certain monoclonal antibodies was demonstrated in vitro by toxin neutralization in tissue culture and in vivo by prolonged survival time in the burned mouse infection model, after passive immunization.

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The results of this study suggest that hypertonic environment induced by SS effectively reduced the oedematous hypergranulation tissue. Clinical trial and postmarketing surveillance data indicate that pilsicainide is generally well tolerated in most patients. Many of them could be secreted into the body fluids in small quantities.

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Analyses of strains containing NMT1 and a faal null mutation indicated that FAA1 is not essential for vegetative growth when an active de novo pathway for fatty acid synthesis is present. Patients presenting with oromyofacial disorders and pain in the head and neck area are often resistant to conventional therapy.

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Despite new insights on objectives, programmes, standards, curriculums and assessment of European postgraduate medical education being published all the time, few papers deal with the social situation of doctors in training across all European countries. Between June 2000 and June 2002, 99 patients with varicocele were submitted to simultaneous A/R sclerotherapy of internal spermatic venous plexus. The data show that some keratin antigens are more often expressed in the irradiated groups and that there may be differences in the degree of antigen expression between squamous cells showing postirradiation dysplasia or postirradiation squamous cell carcinoma and squamous cells showing irradiation atypia. Because the prevention of infection with BVD virus on communal pastures does not seem feasible, it is recommended that all calves born to cows from such pastures be tested for BVD antigen.

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We found a lower prevalence of brain magnetic resonance imaging abnormalities in isolated optic neuritis than previous studies have reported. Knowledge transfer is a relatively new concept in sports medicine and its influence on enhancing concussion education is not well known. Isolation of the right subclavian artery in interrupted aortic arch.

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In this paper we describe the case of a 52-year-old patient with upper and lower limb ischaemia who presented with grade III ischaemia in the left lower limb. The role of the peripheral block is discussed in relation to loss of tension in prolonged voluntary contraction. Demographic data, medical, operative, and postoperative findings, and information regarding complications were compared between these two groups. Carotid angiogram showed almost total occlusion of the left arteria cerebri media. Case report: Cystoscopic use of cyanoacrylate glue for bleeding during transurethral resection of bladder tumors.

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To present the oncological and functional outcomes of salvage focal (SFC) and salvage total (STC) cryoablation for recurrent prostate cancer (PCa) after failed primary radiotherapy. A minority of Type 1 A diabetes patients were obese at initial diagnosis. Hyperosmotic stress induces cisplatin sensitivity in ovarian cancer cells by stimulating aquaporin-5 expression.

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Group size in folivorous primates: ecological constraints and the possible influence of social factors. Both milk-alkali syndrome and intoxication of vitamins A and D were ruled out. Nuclear dynamics in resonant electron-molecule scattering beyond the local approximation: Vibrational excitation and dissociative attachment in H2 and D2. There is some evidence that HRT, DHEA, BP lowering in patients without prior cerebrovascular disease, statins, vitamin B6 and procaine are NOT helpful. Both current and historical events can lead to reduced fitness on some hosts.

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They showed an increase of polyclonal IgM, and positivity for IgM anti-cardiolipin or rheumatoid factors, respectively. This paper describes a clinically based scale elaborated for the evaluation of drug taking behaviour. The role of genomic imprinting in carcinogenesis and cancer susceptibility is examined in this review. B cell lineage developmental regulator genes, Ebf1 and Pax5, appeared to be transcriptionally repressed by bivalent domains before lineage commitment. nonbacteriolytic antibiotics) and interfering in the generation of host-derived cytotoxins.

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This paper presents a systematic methodology for the pooling and analysis of previously conducted epidemiologic studies. Even less attention has been paid to the lasting relationships of couples of color and to gay male and lesbian couples.

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Hypoglycemia due to serum-complexed insulin in a patient with diabetes mellitus. With or without preeclampsia, women carrying twins have significantly higher serum uric acid levels than their singleton counterparts, which suggests a need for separate normative values for twin gestations. Psychoeducation for major depressive disorders: a randomised controlled trial.

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Diurnal variations in the reaction to bronchodilator drugs in patients with chronic bronchitis Estimation of respiratory functions by analysis of expired gas and blood gas during artificial ventilation and general anesthesia One PD was treated with closed reduction but in three cases of PFD operative reduction was necessary. On the basis of the extent to which antisense oligonucleotides can cause cleavage of RNAs at imperfectly matched target sites, we conclude that in this system it is probably not possible to obtain specific cleavage of an intended target RNA without also causing at least the partial destruction of many nontargeted RNAs. Cytochemical study showed that amoeboid microglial cells in the embryonic brains were stained for non-specific esterase.

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The enzyme is subject to carbon source control by easily metabolizable sugars. Here the excited state landscape of metal centered light harvester-catalyst pairs is explored using density functional theory calculations. TBX2 represses PTEN by directly binding to the promoter and recruiting the histone deacetylase, HDAC1. In addition, it suppressed the angiogenesis of xenograft tumor in nude mice, which concurred with the inhibition of tumor growth.

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The ability of high-density lipoprotein (HDL) to inhibit the oxidation of LDL (and cell membranes) and promote macrophage cholesterol efflux through the action of several of its associated proteins, particularly paraoxonase-1 (PON1), reduces the inflammation associated with atherosclerosis. X-Pro dipeptidyl-aminopeptidase (EC 3.4.14.1) purified homogeneously from the human submaxillary gland was proved to hydrolyze N-terminal dipeptide Arg1-Pro2 and subsequent dipeptide Lys3-Pro4 from substance P (Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-gly-Leu-Met-NH2).

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Mice were primed with IgE, followed by injection of artificial allergens to evaluate their in vivo allergenic activity. Parental support was inversely related to substance use through several pathways.

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Job seniority, but not specific tasks, was associated with CTS symptoms. Existing research data of the transcription factors (TFs) and miRNAs is disperse and unorganized, which prevents researchers from investigating the mechanism and analyze regulatory pathways of MM systematically. However, in the spontaneously diabetic insulin-dependent BB/E rat we found that intraperitoneal implantation of microencapsulated islets had only a short-lived effect on hyperglycaemia. Second-harmonic generation based on quasi-phase matching: a novel configuration. Treatment appears to have significant association with post-treatment utility.

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Characterization of an extracellular biofunctional alginate lyase from marine Microbulbifer sp. Binge eating in morbidly obese individuals appears to be associated with a lack of effortful control. A CI should be considered in all patients with CS and severe sensorineural hearing loss.

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Gastric cancer is the second most common fatal malignancy in the world. An experimental study of radial-ulnar deviation and flexion-extension.

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Toxic shock syndrome may result from postoperative staphylococcal wound infection. Although thrombotic occlusion of small vessels in thrombocytosis is allegedly well recognized, it has been reported only rarely. A minimal BRE (-290 to -273) that is sufficient to detect in vitro sequence-specific binding of protein complexes in crude extracts prepared from C. Nosocomial infections continue to be a major complication of assisted ventilation in neonates. Re: Removal of a bent intramedullary nail with a posttraumatic sagittal plane deformity.

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Brownian dynamics simulations for interacting colloids in the presence of a shear flow. Effects of naloxone on d-amphetamine- and apomorphine-induced behavior. Regional coronary flow in ml/min measured with conventional coronarography To systematically evaluate the effectiveness of acupuncture for treating or preventing allergic rhinitis (AR).

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Effect of exogenously incorporated fatty acids on effector cell function in cell-mediated cytolysis. Normative comparisons may be sufficient to elicit behavior change, and inclusion of select additional components may not yield significant improvements in outcomes.

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The yield of purified and matured enzyme was approximately 50 mg/liter, and it was shown that rDPPI and HT-rDPPI were active against both a dipeptide-p-nitroanilide substrate and human growth hormone N-terminally extended with an Ala-Glu dipeptide. After therapy, metastatic lesions were remarkably reduced in size according to various imaging techniques, and the serum CEA level dramatically decreased from 249 ng/ml to 5.2 ng/ml. The Michigan Hand Outcomes Questionnaire, however, also indicated a substantial amount of residual impairment in all domains, including activities of daily living and pain.

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Clinical implications of the rare thyroid carcinoma which is indistinguishable from a follicular adenoma. In addition, the presence of Fisp12 promotes endothelial cell survival when cells are plated on laminin and deprived of growth factors, a condition that otherwise induces apoptosis.

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30 mothers, 17 midwives, four neonatal nurses, three paediatricians, three senior house officers and 3 healthcare assistants were interviewed in the postnatal ward and newborn-baby unit over a period of nine months in 2002. The effects of temperature on various properties of the isolated enzyme were studied.

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A discussion of the present limits and of the existing solutions clearly shows that the method can only be developed at the expense of more elaborate systems such as simultaneous detection channels (quite well suited to the STEM instruments). Twenty-five patients, followed for a mean time of 36 months (9-95 months), were included. Linoleic acid (LA) and its hydroperoxide 13-L-hydroperoxylinoleic acid (LOOH) prepared with soybean lipoxygenase inhibited the response of GABARs in the presence of GABA at high concentrations. This before and after study was conducted in two large Canadian tertiary care EDs and included adult patients with suspected severe infection that met at least two systemic inflammatory response syndrome (SIRS) criteria. We have at our disposal three methods specifically designed for the evaluation of structural damage in SA: the BSARI (Bath Ankylosing Spondylitis Radiology Index), the SASSS (Stoke Ankylosing Spondylitis Spine Score) and a modification of the latter.