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The presence of dyspnoea, tachycardia and desaturation at triage should heighten the index of suspicion for H1N1 (2009)-related complications. The evolutionary trajectories of trade-offs are ultimately governed by the evolution of the underlying physiological processes of the acquisition and subsequent allocation of resources. Interestingly, p19KO mice had lower numbers of IL-17-producing splenic cells than their WT counterparts.

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The effect of retinoic acid on proteoglycan biosynthesis in bovine articular cartilage cultures. Newly organized colorectal cancer screening programs in economically developed countries with a high burden of colorectal cancer may provide pathways to reduce these disparities over time. The results of tests for withdrawal responses and scores based on weight bearing suggest that a surgical incision of the rat foot causes a reliable and quantifiable mechanical hyperalgesia lasting for several days after surgery. At day 10 post partum the number of glucokinase expressing cells, which appear to be localized preferentially in the periportal zone, increases. Cerebral white matter hyperintensity (WMH) is highly prevalent in the elderly population, and increases the risk of dementia and stroke.

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The clinical study of the newly developed bacteriophage preparations in the course of the treatment of purulent inflammatory diseases in 109 patients has revealed that the preparations are not reactogenic and exhibit sufficient effectiveness in the therapy of ozena, rhinoscleroma and Klebsiella infections with different localization of the infectious process. Only strains of Streptococcus gordonii and Actinomyces viscosus bound amylase, and strains of A. Mutagenesis of apobec-1, the catalytic subunit of the mammalian apolipoprotein B mRNA editing enzyme, reveals distinct domains that mediate cytosine nucleoside deaminase, RNA binding, and RNA editing activity.

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The synthesis of a small heat shock/alpha-crystallin protein in Artemia and its relationship to stress tolerance during development. Pancreatic pseudocysts located in the liver: a systematic review of the literature. Infections of the nervous system are mostly fatal, and the source and route of infection are currently unknown.

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Downregulation of Bcl-2 sensitises interferon-resistant renal cancer cells to Fas. Trichloroacetic acid precipitation by ultracentrifugation to concentrate dilute protein in viscous solution. As DCL4-dependent pathways play a key role in rice development, the expression of P1 viral proteins was associated with the same severe developmental defects in spikelets as in dcl4 mutants. Similar clinical phenotypes have been reported with respect to defects in several LPL-associated proteins. Both increased and decreased platelet adhesion to thermally injured subendothelium is caused by denaturation of von Willebrand factor.

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Leydig cell numbers, daily sperm production, and serum gonadotropin levels in aging men. This patient-level pooled analysis included 52 prospective, randomized, double-blind parallel-group studies from the Celecoxib Clinical Database. The aim of this study was to see whether and how cognition predicts outcome in recent-onset schizophrenia in a large range of domains such as course of illness, self-care, interpersonal functioning, vocational functioning and need for care.

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Studying early modern medico-legal testimonies can enrich our understanding of witnessing, the focus of much research in the history of science. Induction of human complement activation without cytolysis by mouse monoclonal antibodies to human leukocyte antigens. ICAM-1-Related Noncoding RNA in Cancer Stem Cells Maintains ICAM-1 Expression in Hepatocellular Carcinoma.

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The regulation in the skin of interleukin-15 (IL-15), a potent modulator of T-cell-mediated immune responses, is not fully understood. These alterations may contribute to the lung dysfunction characteristic of this disorder. We especially focused on the myelin sheaths and astrocytes in the intraocular optic nerve (ION) and its adjoining parts. Understanding the anatomy and pathology of the genital ductal system will help in the diagnosis of disease entities related to male infertility. Mechanical force can be applied on a continuum from none to very severe, and the extent of brain injury is related to the severity of this force.

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As we studied the reactions within the pH range of 3.0 to 9.66, we obtained the following results: lectin binding almost independent from pH (FITC-Con A, -PHA, HPA), fluorescence intensity dependent on pH (TRITC-Con A, FITC-LCA, -GCA), binding pattern dependent on pH (FITC-LCA, GCA). The fascinating parallels that become evident calls for the development of further animal models to address specific questions that could have implications in disease treatments targeting the VSP. A widely accepted tenet of evolutionary biology is that spontaneous mutations occur randomly with regard to their fitness effect.

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To investigate the effect of a combination of carnosine and aspirin eye drops on the progression of diabetic cataract formation induced by streptozotocin (STZ). These results argue strongly against a one-carrier model for transport of folate compounds. Understanding the complex anatomical variations of these uncommon lesions is important for management.

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Advancements in the pathogenesis of asthma are beginning to define a role for the leukotrienes. Four years later, during their diagnostic radiology residency, evaluations of performance were gathered on these applicants from their residency director. We present a unique case in which a patient on chronic metoclopramide therapy developed sulfhemoglobinemia that resolved with subsequent discontinuation of the drug. We elected to transpose the nipple as a full-thickness graft, but consideration also might be given to use of an inferiorly based pedicle flap. Decreases in PcjO2 from previously stable levels occurred over three to four minutes before loss of blood pressure.

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Base substitutions and deletion at A20 also impaired the arginine charging activity by over 50-fold. We suggest a 10-item version of the AES that may be employed for assessing apathy in patients with SAH and stroke. The findings indicate that consultation with a religious leader on organ donation is an important source of information for the community, providing an opportunity to improve the current organ donation rates. Good research practices for measuring drug costs in cost-effectiveness analyses: an international perspective: the ISPOR Drug Cost Task Force report--Part VI.

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Upon incubation at 37 degrees C, this cell-associated immunoglobulin is shed slowly into the medium. Of 980 cases of tuberculosis diagnosed in Stockholm County during the 9.5 year period, 1982 to June 1991, 66 were cases of genito-urinary tuberculosis. The current review summarises experiments suggesting how paraoxonase-1 activity and expression are altered in liver diseases, and their relationships with the monocyte chemoattractant protein-1 and inflammation. The deduced amino acid sequence displays strong identity/similarity with other cyanobacterial GroES and GroEL proteins. Gastrointestinal presentation and outcome of perinatal cytomegalovirus infection.

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Bmabs have been purified from mouse ascites by ammonium sulfate precipitation and affinity chromatography on immobilized peptide, modelling corresponding IL 2 epitope. Ventricular diverticula formation in captive parakeet auklets (Aethia psittacula) secondary to foreign body ingestion. Although the factor(s) accounting for the antiaggregatory effect of diabetic plasma has not yet been characterized, it is possible that the accumulation of sorbitol in erythrocytes is related to the generation of the factor(s). Pre-eclampsia is a multisystem disorder, peculiar to and frequent in human pregnancy. A specific activity of 18.9 nmoles X min-1 X mg-1 protein with 1-chloro-2,4-dinitrobenzene was estimated for the GSH-S-Trs.

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The fixed appliance comprised of brackets, bands, buccal tubes, lingual sheath, transpalatal arch and wires composed of Ni-Ti and stainless steel. We reviewed our experience with such procedures and report on the objective and symptomatic long-term results. Frequency of osteoporosis varies notably according to the skeletal zone considered.

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Air samplers, sponge swabs and Replicate Organism Detection and Counting (RODAC) contact plates were used for environmental sampling. A yeast factor, GRF10 (also known as PHO2 and BAS2), that promoted high-affinity binding of SWI5 in the presence of a large excess of nonspecific carrier DNA was purified.

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Does wearing dentures change sensory nerve responses under the denture base? In in vitro study, FUT (5 micrograms/ml) inhibited the activation of C4 more strongly than heparin (100 U/h), and larger dose of FUT (50 micrograms/ml) inhibited the activation of C3. A DNA probe containing part of the C lambda locus was isolated from a human chromosome 22 genomic library, and a series of rodent X human somatic cell hybrids (each of which contained different translocated parts of chromosome 22) were constructed and characterized.

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Two regions of the proteoglycan, the hyaluronan-binding region and the glycosaminoglycan-rich region of the core protein, were measured, by immunoassay, in knee joint synovial fluids of patients with rheumatoid arthritis or reactive arthritis. Observations from the White House Conference: panel presentation. However, the image resolution is limited, and the histopathology of these lesions is difficult to determine. Anatomic dissection of the posterior interosseous nerve in 26 cadaver forearms was performed to assess variability in location, diameter, and branching patterns of the nerve.

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This study explored some of the problems associated with current procedures for the ascertainment of suicide. AUCs correlated significantly with nadir leucopenia and grade 4 diarrhea.

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Induction of immune tolerance to caseins and whey proteins by oral intubation in mouse allergy model. The model produces relevant clinical output and validation of quantitative data in normal physiology and qualitative directions in simulation of pathological states show good agreement with published data.

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At about 90 days of age, each animal was injected with estrogen and progesterone and tested for female sex behavior. Our results suggest that flagellin may play a role in the in vitro interaction of BA2103 with cellular fibronectin, and GroEL can be an accessory protein in this process.

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The recommendations regarding non-ST segment elevation acute coronary syndrome have been reviewed. Mainstream psycholinguistic research on subject-verb agreement processing has emphasized the purely formal and encapsulated nature of this phenomenon, positing an equivalent access to person and number features. The protective effect of conditioning on noise-induced hearing loss is frequency-dependent.

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However, only in few cases a combined transfrontal and subfrontal approach is indicated. The PD patients show a wide range of clinical outcomes characterised mainly by intractable skin ulcers, mental retardation and recurrent respiratory infections. Altogether, these results indicate the existence of a CT lifecycle in human mononuclear cells and warrant further studies to investigate the role of adrenergic autoregulatory mechanisms in modulation of the immune response and in the pathogenesis of diseases involving the immune system. Evidence for a possible causal relationship between exposure to electromagnetic fields (EMF) emitted by high voltage transmission (HVT) lines and neurobehavioral dysfunction in children is insufficient. A case of a malignant parotid salivary gland nerve sheath tumour is reported in a 12-year-old girl who developed a right parotid mass.

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No case manifested evidence of malignant lymphoproliferative progression. IgG antibody monospecific to GD1b may preferentially bind to large primary sensory neurons, causing sensory ataxic neuropathy. The dose range for both peptides was selected to lie between 0.016 and 0.32 nmol. Reinforcement of bone cement around prostheses by pre-coated wire coil: a finite element model study.

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As a result of these findings, a revised hypothesis is suggested for the locations and possible functions of mAChR in regulation of growth in corneal and other cells. Although, primary cells often more closely resemble the in vivo cells, they may have only a finite replicative life span before they reach senescence. This suggests that the results obtained in EC cells (Simeone et al., 1990, 1991) reflect what occurs in vivo. We examined GATA-4 in 76 formalin-fixed, paraffin-embedded canine testicular tumors, including 21 Sertoli cell tumors (SCT), 28 Leydig (interstitial) cell tumors (LCT), 24 seminomas (GCT), and 3 mixed germ cell sex cord-stromal tumors (MGSCT). Here we show that breast cancer metastasis to the brain involves mediators of extravasation through non-fenestrated capillaries, complemented by specific enhancers of blood-brain barrier crossing and brain colonization.

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We found a high proportion of unipolar illness in the relatives of bipolar probands and bipolar illness in the relatives of unipolar probands, inconsistent with the present dichotomous classification of affective disorders. Comparative evaluation of topical antiseptic/antimicrobial treatment on aspects of wound repair in the porcine model. We studied a multiplex consanguineous Jordanian family by homozygosity mapping and exome sequencing, then used patient-derived fibroblasts to examine functional consequences of the mutation we identified in vitro. hinzii are virulent in turkey poults and may asymptomatically colonize chicks, and suggest this agent may be of concern to poultry producers. Lung cancer treatment rates and the role of the lung cancer nurse specialist: a qualitative study.

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Activity-dependent changes in the number of postsynaptic glutamate receptors underlie aspects of synaptic plasticity and provide a mechanism for information storage in the brain. Treatment of surgically resectable non-small-cell lung cancer in elderly patients. Benign congenital muscular dystrophy with autosomal dominant heredity: problems of classification. In this study, we compared the postsurgical survival of muscle-invasive UTUC patients treated with ONU or with laparoscopic nephroureterectomy (LNU), using the multi-institutional national database of the JUA.

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DMC was developed at Artann Laboratories (West Trenton, New Jersey, USA) for the rapid assessment of changes in the composition of serum. Skin biopsies from 119 patients who received HES of various preparations and cumulative dosage were obtained 30 min to 130 months after infusion therapy. About one-third knew about living wills, but only 5 percent had one. Lipid-Protein Interactions in Sarcoplasmic Reticulum: A Disrupted Secondary Lipid Layer Surrounds the Ca-ATPase. Phthalates comprise a large class of chemicals used in a variety of consumer products.

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TGF-beta increased the synthesis of total protein and collagen of all cells without changing the pattern of interstitial collagens. Patients with Tako-tsubo syndrome most frequently develop acute LV failure, pulmonary edema, rhythm and conductive disturbances and apical thrombosis. pylori strains harbor a type IV secretion system (T4SS) encoded by the cag pathogenicity island.

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Ethical issues in community-based cancer control: considerations in designing interventions. Specificity of targeting can be modulated by the requirement for post-translational modifications such as phosphorylation, hydroxylation or oxidation of the substrate and, in some cases, the ligase itself. A multi-species indirect immunosorbent assay (iELISA) using Brucella S-LPS antigen was developed.

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Nerve growth factor stimulation of p42/p44 mitogen-activated protein kinase in PC12 cells: role of G(i/o), G protein-coupled receptor kinase 2, beta-arrestin I, and endocytic processing. We have used the polymerase chain reaction to isolate fragments of Ty1-copia group retrotransposons from a wide variety of members of the higher plant kingdom. The immunoreactive LH content of the female PT was determined at three phases of the estrous cycle: diestrus, afternoon of proestrus and estrus. Early-onset BSI were discovered within 48 hours from birth, and late-onset BSI were those that occurred thereafter.

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These were numerous in the endothelial cells of the inter-Leydig cell capillaries and the non-fenestrated part of the intramural capillaries. The enzyme activity was found specifically associated with the detergent insoluble skeleton of the plasma membranes from which it cannot be dissociated by conventional methods. We studied the isoforms with the use of two-dimensional gel electrophoresis.

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An association between phlebotomine sandflies and aphids in the Peruvian Andes. Experience of at least one job loss increased the risk of premature mortality. Buthionine sulfoximine enhancement of arsenic trioxide-induced apoptosis in leukemia and lymphoma cells is mediated via activation of c-Jun NH2-terminal kinase and up-regulation of death receptors. Effect of high shuntflows during portofemoro-subclavian venovenous bypass in human orthotopic liver transplantation.

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An urban ALS paramedic service with on-line physician medical command rotating on a monthly basis among three hospitals. The defenses that individuals mobilize to deal with their death-anxiety are often maladaptive.

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Trials in which passengers wore a stocking on one leg but not the other, or those comparing stockings and another intervention were also eligible. The expression of Dpr is under perR (peroxide stress response regulator) control. Central neurogenic hyperventilation in an awake patient with a pontine glioma. The DNA photocleavage characteristics of this series of cationic porphyrins were found to depend on the structural characteristics of the poprhyrins such as (a) length of the side chain of the cationic substituents (2 vs 4), (b) the position of the side chain on the porphyrin ring (4 vs 7), and (c) the presence of the chelating metal in 3, 5, and 8 as compared to the nonmetallo porphyrins 2, 4, and 7, respectively.